Acknowledgments We thank W Bian, X Wang and F Zhang from Cell Biology Facility for support with cell sorting, Y Chen and X Ding from the Stem Cell Core Facility at SIBCB for support with cell cultures, H Li, M Li, H Deng, R Hou and H Xiao from Shanghai Biochip Company for sequencing data analysis, and Y Jin and Y Zeng from SIBS for providing antibodies. This study was supported by the Ministry of Science and Technology of China (2014CB964803, 2012CB944700, 2015AA020307 and 2013CB967103) and the National Natural Science Foundation of China (91319310, 31225017, 31530048, 81430029, 81490743, 31371453 and 31571548).
Haploid embryonic stem cells (haESCs) have been recently generated from parthenogenetic (PG) or andro- genetic (AG) blastoeysts of different mammals, including mouse, rat and monkey, enabling genetic screening a...