BACKGROUND Despite therapeutic benefits,discontinuation of tirzepatide is common in randomized controlled trials(RCTs)due to adverse events(AEs)and other causes.No previous systematic reviews have explored the reasons...
Hepatic encephalopathy(HE)is one of the main complications of cirrhosis,characterized by a wide spectrum of neuropsychiatric alterations that lead to an increase in mortality,morbidity and recurrent hospitalizations.D...
The timely introduction and adjustment of the appropriate drug in accordance with previously well-defined treatment goals is the foundation of the approach in the treatment of inflammatory bowel disease(IBD).The thera...
BACKGROUND Secondary sclerosing cholangitis,characterized by biliary obstruction,can be caused by drugs such as immune checkpoint inhibitors(ICIs).While there a few reports of sclerosing cholangitis after immune check...
Excessive acute inflammatory response in coronavirus-induced disease 2019(COVID-19)patients results in multiple organ injury,especially acute respiratory distress syndrome(ARDS),contributing to a high mortality of the...
Long-term antiviral treatment of chronic hepatitis B patients has been proven to be beneficial in reducing liver-related complications.However,lengthy periods of daily administration of medication have some inevitable...
Nucleos(t)ide analogs(NUC)are the first-line therapy for patients with chronic hepatitis B(CHB)recommended by most current guidelines.NUC therapy decreases progression of liver disease,reduces the risk of liver-relate...
the Guangxi Medical and Health Project[Z20170126];the National Natural Science Foundation of China[Grant numbers 11971479,81502862,81460510,81360442,and 91546203];Guangxi Science and Technology Bureau[Grant number AB16380213];Guangxi Bagui Honor Scholarship,Ministry of Science and Technology of China[2018ZX10721102-006 and 2017ZX10201101];Guangxi Key Laboratory of AIDS Prevention Control and Translation,and Chinese State Key Laboratory of Infectious Disease Prevention and Control.
Combination antiretroviral therapy(ART)reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication,enhancing immune recovery,and preventing the onset of opportu...
Background:It is known that'drop out'from human immunodeficiency virus(HIV)treatment,the so called lost-to-follow-up(LTFU)occurs to persons enrolled in HIV care services.However,in sub-Saharan Africa(SSA),the risk fac...
The purpose of this study is to prepare a nursing protocol for preventing discontinuation of treatments using a method other than physical restraint during acute exacerbation of chronic heart failure in patients with ...