Production of economically viable bioethanol is potentially an environmentally and financially worthwhile endeavor.One major source for fermentable sugars is lignocellulose.However,lignocellulosic biomass is difficult...
The authors are grateful to funding sources from the Office of Science(BER),U.S.Department of Energy(DE-SC0010352);the National Science Foundation(MCB-1553721);the Institute for Collaborative Biotechnologies through grants W911NF-09-0001 and W911NF-19-D-0001 from the U.S.Army Research Office;and the Camille Dreyfus Teacher-Scholar Awards Program.All authors acknowledge support from the California NanoSystems Institute(CNSI)Challenge Grant Program,supported by the University of California,Santa Barbara and the University of California,Office of the President.SPG also acknowledges support from the National Science Foundation Graduate Research Fellowship Program under Grant DGE 1144085.We thank Prof.Robert Kelly for providing us with T.maritima DNA.The authors acknowledge the use of the Biological Nanostructures Laboratory within the California NanoSystems Institute,supported by the University of California,Santa Barbara and the University of California,Office of the President.
Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via synergistic action of multiple enzymes fused to a protein scaffold.Through templating key protein domains(cohesin and dockerin...