Supported by the International Cooperation Project of Department of Science and Technology of Shanxi Province(No.201903D421057);the Youth Fund Project of Department of Science and Technology of Shanxi Province(No.201901D211485)。
Objective:To investigate the effects of astragalosideⅣ(AS-Ⅳ)on podocyte injury of diabetic nephropathy(DN)and reveal its potential mechanism.Methods:In in vitro experiment,podocytes were divided into 4 groups,normal...
the National Natural Science Foundation of China(Nos.22271257,32202063,and 21902148);Natural Science Foundation of Henan(No.232300421096);the National Key R&D Program of China(No.2024YFE0105200);Start-up Research Fundation of Henan University of Technology(No.2021BS053);the Innovation and Technology Commission of Hong Kong,The Hong Kong Polytechnic University;the support from MICIU/AEI/10.13039/501100011033;ERDF/EU(No.PID2022-138724NB-I00);the Xunta de Galicia/ERDF(No.GRC ED431C 2020/09).
Recent studies support that magnetic chiral nanozymes,integrating the features of chirality,magnetism,and enzyme-like catalysis,provide new insights into the synthetic methodologies and applications of chiral nanozyme...
the National Key Research and Development Program of China(Nos.2022YFA1204500 and 2022YFA1204502);the National Natural Science Foundation of China(Nos.22293043,51932001,52372170,and 92163209);the Beijing-Tianjin-Hebei Basic Research Cooperation Special Project(No.B2024204027);IPE Project for Frontier Basic Research(No.QYJC-2023-08).
Enzyme-like metal atomic site catalysts are promising alternatives of platinum group metals for oxygen reduction reaction(ORR)in fuel cell application.The local coordination structure at metal atomic sites plays a dom...
supported by the National Natural Science Foundation of China(Nos.52072152,and 51802126);the Jiangsu University Jinshan Professor Fund;the Jiangsu Specially-Appointed Professor Fund;Open Fund from Guangxi Key Laboratory of Electrochemical Energy Materials,Zhenjiang“Jinshan Talents”Project 2021;China PostDoctoral Science Foundation(No.2022M721372);“Doctor of Entrepreneurship and Innovation”in Jiangsu Province(No.JSSCBS20221197);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Nos.KYCX22_3645 and KYCX24_3964).
Natural enzymes are highly efficient catalysts with strong substrate specificity,making them ideal for biomedical applications.However,they often face issues such as variability,high costs,challenging preparation proc...
Biocatalysis with nicotinamide adenine dinucleotide phosphate(NADP)-dependent oxidoreductases faces a challenge in improving the efficiency of the costly cofactor utilization.Although enzyme fusion can offer cofactor ...
the National Natural Science Foundation of China(NSFC)(Grant Nos.52108307 and 52178319);the Natural Science Foundation of Fujian Province,China(Grant No.2022J05020).
Biomineralization based on bacterial enzyme induced carbonate precipitation(BEICP)process is a promising alternative to cement-based ground treatment technology.The bacterial urease used in BEICP process is usually ul...
This work was funded by the National Key Research and Development Program of China(No.2020YFA0210800,H.H.Y.);the Major Project of Science and Technology of Fujian Province(No.2020HZ06006,H.H.Y.);the National Natural Science Foundation of China(Nos.22421002,22027805,and 22334004,H.H.Y.,Nos.22107019,and 22277011,Z.W.C.,No.22404025,Y.H.Y.);the Research project of General Administration of Customs of PRC(No.2024HK008,X.H.Z.).
Bioorthogonal catalysis mediated by abiotic transition metal catalysts(TMCs)is emerging as a momentum-gathering strategy for in situ generation of therapeutics.However,the unpredictable leakage and deposition of TMCs ...
This work was supported by the National Key Research and Development Program of China(No.2021YFB3500904);the National Natural Science Foundation of China(No.22475173);the Key Research and Development Program of Shaanxi(No.2024SF-YBXM-439);Authors also acknowledge the support from Fundamental Research Funds for the Central Universities(No.D5000210635).
Designing highly performed uricase-like nanozymes through enzymatic-like colorimetric analysis system is of vital significance for the quantitative detection of uric acid(UA).Herein,series of Ce-UiO-66 nanozymes with ...
Enzyme catalysis is a promising way to produce chiral products in a green and sustainable way.However,the high cost of cofactors and their relatively low recycling efficiency hinder the widespread application of enzym...
In recent years,chiral inorganic nanomaterials have become promising candidates for applications in sensing,catalysis,biomedicine,and photonics.Plasmonic nanomaterials with an intrinsic chiral structure exhibit intrig...