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作品数:166被引量:662H指数:12
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Up-regulation of miR-10a-5p expression inhibits the proliferation and differentiation of neural stem cells by targeting Chl1
《Acta Biochimica et Biophysica Sinica》2024年第10期1483-1497,共15页Juan Zhang Lihong Yang Yuqing Sun Li Zhang Yufei Wang Ming Liu Xiujuan Li Yuxiang Liang Hong Zhao Zhizhen Liu Zhiyong Qiu Ting Zhang Jun Xie 
supported by the grants from the National Natural Science Foundation of China(No.81671462);the Fund for Shanxi“1331 Project”Key Subjects Construction(No.1331KSC);the Natural Science Foundation of Shanxi Province(Nos.20210302124184 and 20210302124016);the Shanxi Province Key Laboratory of Birth Defects and Cell Regeneration and Research Project Supported by Shanxi Scholarship Council of China.
Neural tube defects(NTDs)are characterized by the failure of neural tube closure during embryogenesis and are considered the most common and severe central nervous system anomalies during early development.Recent micr...
关键词:neural tube defects retinoic acid miR-10a-5p cell adhesion molecule L1-like(Chl1) ERK1/2 MAPK signaling pathway 
Piperlongumine Inhibits Zika Virus Replication In vitro and Promotes Up-Regulation of HO-1 Expression, Suggesting An Implication of Oxidative Stress被引量:5
《Virologica Sinica》2021年第3期510-520,共11页Weizhi Lu Linjuan Shi Jing Gao Huimin Zhu Ying Hua Jintai Cai Xianbo Wu Chengsong Wan Wei Zhao Bao Zhang 
supported by the National Natural Science Foundation (Nos. 31670168, 31470271 and 81730110);National Key R&D Program of China (Grant No. 2018YFC1602206);Guangdong Provincial Science and Technology (No. 2018B020207006)。
Owing to the widespread distribution of mosquitoes capable of transmitting Zika virus, lack of clinical vaccines and treatments, and poor immunity of populations to new infectious diseases, Zika virus has become a glo...
关键词:Piperlongumine Heme oxygenase-1(HO-1) Reactive oxygen species Zika virus(ZIKV) Human brain microvascular endothelial cells 
Up-regulation of micro RNA-210 inhibits proliferation of hepatocellular carcinoma cells by targeting YES1被引量:4
《World Journal of Gastroenterology》2015年第46期13030-13041,共12页Weiqi Tan Seng-Gee Lim Theresa MC Tan 
Supported by Biomedical Research Council and Ministry of Education(Tier 1)awarded to Tan TM
AIM: To determine the expression of micro RNA-210(mi R-210) in hepatocellular carcinoma(HCC) and to examine its role using HCC cells.METHODS: The expression of mi R-210 was determined in 21 pairs of HCC samples and th...
关键词:Micro RNA-210 HEPATOCELLULAR CARCINOMA Proliferati 
α-MSH inhibits TNF-α-induced maturation of human dendritic cells in vitro through the up-regulation of ANXA1被引量:3
《Acta Biochimica et Biophysica Sinica》2011年第1期61-68,共8页Yan Min Deping Han Zhanjiang Fu Honghai Wang Lirong Liu Yeping Tian 
α-Melanocyte-stimulating hormone (α-MSH), an antiinflammatory and immunomodulatory neuropeptide, has been shown to be effective in the experimental treatment of autoimmune diseases and allograft rejection. However...
关键词:α-melanocyte stimulating hormone dendritic cells annexin A1 
Up-regulation of SEPT7 Gene Inhibits Migration and Invasion of Human Glioma Cells in vitro and in vivo
《中国肺癌杂志》2009年第6期671-671,共1页Song XU Zhifan JIA Chunsheng KANG Qiang HUANG Guangxiu WANG Xiaozhi LIU Xuan ZHOU Peng XU Peiyu PU 
The aim of this study was to explore the potential role of SEPT7 in glioma cell invasion. From in vitro experiments, we observed that the migratory and invasive abilities were inhibited in human glioblastoma U251MG an...
关键词:肺癌 治疗 疗效 临床 
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