PEPTIDOME

作品数：7被引量：14H指数：2
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Peptidome data-driven comprehensive individualized monitoring of membranous nephropathy with machine learning
《Chinese Chemical Letters》2024年第5期402-406,共5页Zixing Xu Ruiying Chen Chuanming Hao Qionghong Xie Chunhui Deng Nianrong Sun 
financially supported by National Key R&D Program of China(No.2018YFA0507501);the National Natural Science Foundation of China(Nos.22074019,21425518,22004017);Shanghai Sailing Program(No.20YF1405300)。
As the most common pathological type of nephrotic syndrome,membranous nephropathy(MN)presents diversity in progression trends,facing severe complications.The precise discrimination of MN from healthy people,other type...
关键词：Membranous nephropathy Serum peptidome Machine learning Disease diagnosis 
Nutritional composition,ultrastructural characterization,and peptidome profile of antioxidant hemp protein hydrolysates
《Food Bioscience》2023年第3期783-793,共11页Sergio Montserrat-de la Paz Fernando Rivero-Pino Alvaro Villanueva Rocio Toscano-Sanchez Maria E.Martin Francisco Millan Maria C.Millan-Linares 
funded by grant P20_00661 from the Andalusian Plan for Research,Development and Innovation(PAIDI)2020;by grant US-1381492 from the European Regional Development Fund(ERDF).
Hemp is the term commonly used to refer to the variety of Cannabis sativa L.cultivated for industrial purposes.The seeds have gained interest in recent years as functional foods due to their nutritional composition an...
关键词：BIOECONOMY Bioactive peptides Cannabis sativa PEPTIDOMICS Proteomic profile 
Dynamic changes of peptidome and release of polysaccharide in sea cucumber(Apostichopus japonicus) hydrolysates depending on enzymatic hydrolysis approaches被引量：2
《Food Science and Human Wellness》2022年第5期1331-1341,共11页Yanchao Wang Yan Song Yaoguang Chang Yanyan Liu Guangning Chen Changhu Xue 
supported by the Fok Ying-Tong Education Foundation (171024);Fundamental Research Funds for the Central Universities (201941005);Fundamental Research Funds for the Central Universities (862001013136)。
Enzymatic hydrolysis has been widely used to produce bioactive hydrolysates from sea cucumber body wall.Here,inspired by the clarification of Apostichopus japonicus genome,we investigated the enzymatic hydrolysis of s...
关键词：Sea cucumber Enzymatic hydrolysis Protein PEPTIDOME POLYSACCHARIDE 
Peptidome profiling of human serum of uveal melanoma patients based on magnetic bead fractionation and mass spectrometry
《International Journal of Ophthalmology(English edition)》2017年第6期939-947,共9页Xiang-Yu Shi Qing Li Wen-Bin Wei Li-Ming Tao 
Supported by the National Natural Science Foundation of China(No.81570891;No.81272981);the Beijing Natural Science Foundation(No.7151003);Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau(No.2014-2-003);Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(No.ZYLX201307)
AIM： To find new biomarkers for uveal melanoma （UM） by analyzing the serum peptidome profile. METHODS： Proteomic spectra in patients with UM before and after operation were analyzed and compared with those of hea...
关键词：uveal melanoma protein biomarker peptidomeprofile magnetic bead fractionation mass spectrometry 
Peptidomic analysis of Chinese shrimp(Fenneropenaeus chinensis) hemolymph by magnetic bead-based MALDITOF MS
《Chinese Journal of Oceanology and Limnology》2013年第2期407-415,共9页王宝杰 刘梅 蒋克勇 张国范 王雷 
Supported by the National Natural Science Foundation of China(No.30600458)
Peptides in shrimp hemolymph play an important role in the innate immune response.Analysis of hemolymph will help to detect and identify potential novel biomarkers of microbial infection.We used magnetic bead-based pu...
关键词：Fenneropenaeus chinensis hemolymph peptidome MALDI-TOF MS WCX-magnetic bead immune-challenged 
Serum peptidome profiling for identifying pathological patterns in patients with primary nephrotic syndrome被引量：7
《Chinese Medical Journal》2012年第24期4418-4423,共6页HUANG Lan-ting WEN Qiong ZHAO Ming-zhe LI Zhi-bin LUO Ning WANG Yong-tao DONG Xiu-qing YU Xue-qing 
This work was supported by gran＇ts from the National Science Fund for Distinguished Young Scholars of China （No. 30925019）, the National Natural Science Foundation of China （No. 30871166）, and the Key Clinical Research Program, Ministry of Health, China （2007）.
Background Renal biopsy is necessary for diagnosing the pathological changes of primary nephrotic syndrome （NS）. However, it is invasive, time-consuming and can not be performed frequent on the same patient. Thus, d...
关键词：nephrotic syndrome SERUM matrix-assisted laser desorption/ionization time-of-flight mass spectrometry  diagnostic model 
Analysis of the urinary peptidome associated with Helicobacter pylori infection被引量：5
《World Journal of Gastroenterology》2011年第5期618-624,共7页Di Xiao Fan-Liang Meng Li-Hua He Yi-Xin Gu Jian-Zhong Zhang 
Supported by The National Science and Technology Pillar Program of the Ministry of Science and Technology of the People’s Republic of China during the Eleventh Five-Year plan period,No. 2007BAID4B02
AIM： To investigate the relationship between urinary peptide changes and Helicobacter pylori （H. pylorl） infection using urinary peptidome profiling. METHODS： The study was performed in volunteers （n = 137） who ...
关键词：Urinary peptidome profiling MB-matrix-assisted laser desorption/ionization time-of-flight massspectrometry Helicobacter pylori Fibrinogen degrada-tion products 
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