PEPTIDOMICS

作品数：16被引量：27H指数：3
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相关领域：理学生物学更多>>
相关作者：魏开华杨松成张学敏刘念王红霞更多>>
相关机构：军事医学科学院更多>>
相关期刊：《World Journal of Biological Chemistry》《Journal of Pharmaceutical Analysis》《Chinese Herbal Medicines》《Frontiers in Biology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划俄罗斯基础研究基金上海市自然科学基金更多>>
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Genomics,transcriptomics,and peptidomics of the greater wax moth Galleria mellonella neuropeptides and their expression in response to lead stress被引量：2
《Insect Science》2024年第3期773-791,共19页Li-Lin Luo Yang Lin Jun-Hong Linghu Wei Gong Yuan-Hong Luo Man Liu Dao-Chao Jin Guy Smagghe Tong-Xian Liu Shun-Hua Gui Tian-Ci Yi 
supported in part by the National Natural Science Foundation of China(32202295);Guizhou Provincial Science and Technology Projects(Qian Ke He Ji Chu-ZK[2022]General 051);Scientific Research Foundation for Talent Introduced in Guizhou University(Gui Da Te Gang He Zi[2021]22);Guizhou Provincial Science and Technology Projects(Qian Ke He Support[2019]2292,Qian Ke He NY[2013]3040).
Neuropeptides are crucial in regulation of a rich variety of developmental,physiological,and behavioral functions throughout the life cycle of insects.Using an integrated approach of multiomics,we identified neuropept...
关键词：Galleria mellonella GENOMICS heavy metal stress NEUROPEPTIDE PEPTIDOMICS TRANSCRIPTOMICS 
Clinical Peptidomics: Advances in Instrumentation, Analyses, and Applications被引量：1
《Biomedical Engineering Frontiers》2023年第1期116-132,共17页Lin Li Jing Wu Christopher JLyon Li Jiang Tony Y.Hu 
The work was primarily supported by research funding provided by the National Cancer Institute(U01CA252965);Eunice Kennedy Shriver National Institute of Child Health and Human Development(R01HD090927 and R01HD103511);National Institute of Allergy and Infectious Diseases(R01AI144168);U.S.Department of Defense(W8IXWH1910926);National Institute of Neurological Disorders and Stroke(R21NS130542).
Extensive effort has been devoted to the discovery,development,and validation of biomarkers for early disease diagnosis and prognosis as well as rapid evaluation of the response to therapeutic interventions.Genomic an...
关键词：doses gained devoted 
Characterization of natural peptides in Pheretima by integrating proteogenomics and label-free peptidomics被引量：1
《Journal of Pharmaceutical Analysis》2023年第9期1070-1079,共10页Xiaoxiao Luo Qirui Bi Dongdong Huang Yun Li Changliang Yao Jianqing Zhang Wenlong Wei Jiayuan Li Zhenwei Li Jingxian Zhang Shen Ji Yurong Wang De-an Guo 
supported by the Key Program of the National Natural Science Foundation of China(Grant No.:82130111);the National Natural Science Foundation of China(Grant No.:81803716);the Qi-Huang Chief Scientist Project of the National Administration of Traditional Chinese Medicine,China(2020);the SIMM-SHUTCM Traditional Chinese Medicine Innovation Joint Research Program,China(Grant No.:E2G809H).
Pheretima,also called“earthworms”,is a well-known animal-derived traditional Chinese medicine that is extensively used in over 50 Chinese patent medicines(CPMs)in Chinese Pharmacopoeia(2020 edition).However,its zool...
关键词：PHERETIMA Natural peptides Label-free peptidomics PROTEOGENOMICS Animal derived medicine 
Nutritional composition,ultrastructural characterization,and peptidome profile of antioxidant hemp protein hydrolysates
《Food Bioscience》2023年第3期783-793,共11页Sergio Montserrat-de la Paz Fernando Rivero-Pino Alvaro Villanueva Rocio Toscano-Sanchez Maria E.Martin Francisco Millan Maria C.Millan-Linares 
funded by grant P20_00661 from the Andalusian Plan for Research,Development and Innovation(PAIDI)2020;by grant US-1381492 from the European Regional Development Fund(ERDF).
Hemp is the term commonly used to refer to the variety of Cannabis sativa L.cultivated for industrial purposes.The seeds have gained interest in recent years as functional foods due to their nutritional composition an...
关键词：BIOECONOMY Bioactive peptides Cannabis sativa PEPTIDOMICS Proteomic profile 
Peptidomic Analysis Reveals that Novel Peptide LDP2 Protects Against Hepatic Ischemia/Reperfusion Injury被引量：1
《Journal of Clinical and Translational Hepatology》2023年第2期405-415,共11页Qun Bao Zhengxin Wang Sheng Cheng Jin Zhang Qiuli Liu Yunpeng Zhang Daqing Cheng Xirong Guo Xingyun Wang Bo Han Peng Sun 
supported by National Natural Science Foundation of China (82070634,82002495);Shanghai Natural Science Foundation (20ZR1451700);SJTU CrossDisciplinary Research Fund in Medicine and Engineering (YG2022QN117);Shanghai Key Medical Specialty Fund (ZK2019A15);Research Fund of Key Laboratory for Translational Research and Innovative Therapeutics of Gastrointestinal Oncology (ZDSYS-2021-04);National Key Research and Development Program (2021YFC2701903).
Background and Aims:Hepatic ischemia/reperfusion(I/R)injury has become an inevitable issue during liver transplantation,with no effective treatments available.However,peptide drugs provide promising regimens for the t...
关键词：Hepatic ischemia/reperfusion(I/R)injury PEPTIDOMICS Peptide LDP2 Apoptosis Autophagy 
Peptidomics as a tool to analyze endogenous peptides in milk and milk-related peptides
《Food Bioscience》2022年第6期1397-1415,共19页Jianting Ning Mohan Li Weiyan Chen Huiwen Zhao Jiali Chen Mei Yang Xueyan Cao Xiqing Yue 
supported by LiaoNing Revitalization Talents Project(grant number XLYC1902083).
As a subset of the proteome, peptidomics is the best tool to analyze peptides in different food matrices. Milk peptides are produced by protease hydrolysis in the mammary gland, which plays an important role in the gr...
关键词：PEPTIDOMICS MILK ENDOGENOUS Bioactive peptides In silico screening 
Peptidomic analysis of whey protein hydrolysates and prediction of their antioxidant peptides被引量：4
《Food Science and Human Wellness》2022年第2期349-355,共7页Jesus Morales García Chibuike C.Udenigwe Jorge Duitama Andrés Fernando González Barrios 
supported and funded by the Gobernación del Cesar-Ministry of Science,Technology,and Innovation through resources for the higher education(grant 736/2015);the Natural Sciences and Engineering Research Council of Canada(NSERC)。
Enzymatic hydrolysis of proteins is a breakdown process of peptide bond in proteins,releasing some peptides with potential biological functions.Previous studies on enzymatic hydrolysis of whey proteins have not identi...
关键词：Whey hydrolysate Antioxidant peptide PEPTIDOMICS PREDICTION 
Collagen derived species-specific peptides for distinguishing donkey-hide gelatin(Asini Corii Colla)被引量：6
《Chinese Herbal Medicines》2021年第2期261-266,共6页Shuo Cai Ke-xuan Zhao Meng-tong Jiang Shu-ying Han Yun-feng Zheng Xun Liu Ming Zhao Jin-ao Duan Rui Liu 
funded by the National Natural Science Foundation of China (No.81973450);the National Key R&D Program of China (No.2018YFC1706100);the Jiangsu Qinglan Project;the Jiangsu “333” Project;the Young Researchers Training Project of China Association of Traditional Chinese Medicine (No.QNRC2C14);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (No.19KJB360020);the Open Project of Chinese Materia Medica First-Class Discipline of Nanjing University of Chinese Medicine (2020YLXK009)。
Objective:As an important food therapy product with traditional Chinese medicine(TCM) applications,donkey-hide gelatin(Asini Corii Colla,ACC) has been used for thousands of years.However,till now few effective strateg...
关键词：Asini Corii Colla Biomarkers COLLAGEN PEPTIDOMICS species-specific peptides 
Identification of zinc-binding peptides in ADAM17-inhibiting whey protein hydrolysates using IMAC-Zn^(2+) coupled with shotgun peptidomics被引量：1
《Food Production, Processing and Nutrition》2021年第1期70-79,共10页M.Chinonye Udechukwu Chi Dang Chibuike C.Udenigwe 
supported by the Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grants(RGPIN-435865-2013 and RGPIN-2018-06839);Canada Foundation for Innovation(CFI)John R.Evans Leaders Fund Infrastructure Grant(Project number:31305).
Food components possessing zinc ligands can be used to inhibit zinc-dependent enzymes.In this study,zinc-binding peptides were derived from whey protein hydrolysates,and their ultrafiltration(>1 and<1 kDa)fractions,pr...
关键词：ZINC Zinc ligands Food protein Bioactive peptides Immobilized metal affinity chromatography Ultrafiltration ADAM17 PEPTIDOMICS Bioinformatics 
Discovery of lung squamous carcinoma biomarkers by profiling the plasma peptide with LC/MS/MS
《Chinese Chemical Letters》2017年第5期1093-1098,共6页Yu Liu Xiao-Hong Xun Jian-Ming Yi Yang Xiang Jie Hua 
financially supported by the National Natural Science Foundation of China(No.21172067);Science and Technology Project of Hunan Province(Nos.2013SK2015,2014SK3017);Scientific Research Key Fund of Hunan Provincal Education Department(No.13A032)
Biomarkers can be used for the screening and clinical diagnosis of cancer,and peptidomics approach has been proven successful in the research of biomarkers.To develop better peptidomic technologies for fast,accurate,a...
关键词：Lung cancer Lung squamous carcinoma Biomarkers Cancer testis antigen Peptidomics 
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