NEUROPEPTIDE

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Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions
《Neural Regeneration Research》2025年第7期1991-1992,共2页Fengwen Huang Stephen Temitayo Bello 
Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodu...
关键词：abundant FUNCTIONS MODULATOR 
The First Non-Chordates QRFP-Like Peptide Receptor Gene in the Cephalopod Sepiella japonica:Identification,Characterization and Possible Role in Food Intake
《Journal of Ocean University of China》2025年第1期195-208,共14页LI Shuang HAO Qing QIU Jiayin ZHOU Xu CHI Changfeng ZHENG Libing 
supported by the National Natural Science Foundation of China(No.31872547);the Natural Science Foundation of Zhejiang Province,China(No.LTGN24C190015);the Excellent Postdoctoral Program of Jiangsu Province(No.314865)。
The novel identified receptor,GPR103,now renamed QRFPR(also referred to as SP9155 or AQ27),is the endogenous receptor for the neuropeptide QRFP(also referred to as 26RFa).The distribution pattern,structure,and biologi...
关键词：NEUROPEPTIDE 26RFa/QRFP QRFP-like peptide receptor CUTTLEFISH Sepiella japonica 
Neuropeptide signaling systems are involved in regulating thermal tolerance in the oriental fruit fly
《Journal of Integrative Agriculture》2024年第12期4147-4160,共14页Yang Yang Hongfei Li Changhao Liang Donghai He Hang Zhao Hongbo Jiang Jinjun Wang 
supported by funding from the National Natural Science Foundation of China(U21A20222 and 32072491);the National Key R&D Program of China(2022YFC2601000);the 111 Project,China(B18044)and the earmarked fund for China Agriculture Research System(CARS-26)。
Neuropeptides and their receptors are involved in the regulation and coordination of various physiological processes in insects.Although various neuropeptides have been identified previously,the corresponding receptor...
关键词：Bactrocera dorsalis neuropeptide receptors sNPF thermal adaptation CRISPR/Cas9 
Neuropeptide ACP is required for fat body lipid metabolism homeostasis in locusts
《Insect Science》2024年第5期1453-1465,共13页Li Hou Siyuan Guo Yuanyuan Wang Shaoye Liu Xianhui Wang 
This study was supported by the National Key R&D Program of China no.2022YFD1400500;the National Natural Science Foundation of China(grant no.31930012 and 32070497);Youth Innovation Promotion Association CAS(no.2021079).
Fat body metabolism plays crucial roles in each aspect of insect life traits.Although neuropeptides have been documented to be one of the major neuroendocrinal regulators involved in fat body metabolism,the detailed r...
关键词：FECUNDITY lipid metabolism METABOLOME NEUROPEPTIDE transcriptome 
Single-cell transcriptomes provide insights into expansion of glial cells in Bombyx mori
《Insect Science》2024年第4期1041-1054,共14页Xiaojing Liu Zhongjie Zhang Bo Hu Kai Chen Ye Yu Hui Xiang Anjiang Tan 
supported by the National Science Foundation of China(32000339,32000336 and 31925007);the Natural Science Foundation of Jiangsu Province(BK20231249,BK20221292 and BK20210880)。
The diversity of cell types in the brain and how these change during different developmental stages,remains largely unknown.The life cycle of insects is short and goes through 4 distinct stages including embryonic,lar...
关键词：brain NEUROPEPTIDE SILKWORM single-cell transcriptome 
Transcriptomic analysis identifies the neuropeptide cortistatin (CORT) as an inhibitor of temozolomide (TMZ) resistance by suppressing the NF-kB-MGMT signaling axis in human glioma
《Genes & Diseases》2024年第3期385-399,共15页Zongze He Bo Peng Qi Wang Jie Tian Ping Liu Jie Feng Yiwei Liao Longyi Chen Ping Jia Jian Tang 
supported by grants from the Department of Science and Technology of Sichuan Province,China(No.23ZDYF2212,23ZDYF2098);the Foundation for Sichuan Provincial People's Hospital(Sichuan,China)(No.2022QN06);Medico-Engineering Cooperation Funds from the University of Electronic Science and Technology of China(No.ZYGX2021YGLH209)and 2022 Tianfu Qingcheng Project,China.
Glioma is a common tumor originating in the brain that has a high mortality rate.Temozolomide(TMZ)is the first-line treatment for high-grade gliomas.However,a large pro-portion of gliomas are resistant to TMZ,posing a...
关键词：CORTISTATIN Glioma MGMT NF-kB pathway TEMOZOLOMIDE 
Genomics,transcriptomics,and peptidomics of the greater wax moth Galleria mellonella neuropeptides and their expression in response to lead stress被引量：2
《Insect Science》2024年第3期773-791,共19页Li-Lin Luo Yang Lin Jun-Hong Linghu Wei Gong Yuan-Hong Luo Man Liu Dao-Chao Jin Guy Smagghe Tong-Xian Liu Shun-Hua Gui Tian-Ci Yi 
supported in part by the National Natural Science Foundation of China(32202295);Guizhou Provincial Science and Technology Projects(Qian Ke He Ji Chu-ZK[2022]General 051);Scientific Research Foundation for Talent Introduced in Guizhou University(Gui Da Te Gang He Zi[2021]22);Guizhou Provincial Science and Technology Projects(Qian Ke He Support[2019]2292,Qian Ke He NY[2013]3040).
Neuropeptides are crucial in regulation of a rich variety of developmental,physiological,and behavioral functions throughout the life cycle of insects.Using an integrated approach of multiomics,we identified neuropept...
关键词：Galleria mellonella GENOMICS heavy metal stress NEUROPEPTIDE PEPTIDOMICS TRANSCRIPTOMICS 
A bird's-eye overview of molecular mechanisms regulating feed intake in chickens-with mammalian comparisons
《Animal Nutrition》2024年第2期61-74,共14页Anastasiia RVolyanskaya Ilya RAkberdin Mikhail AKulyashov Ivan SYevshin Michael NRomanov Elena IShagimardanova Oleg AGusev Fedor AKolpakov 
supported by the Ministry of Science and Higher Education of the Russian Federation(Grant No.075–15–2021–1344).
In recent decades,a lot of research has been conducted to explore poultry feeding behavior.However,up to now,the processes behind poultry feeding behavior remain poorly understood.The review generalizes modern experti...
关键词：CHICKEN Feed intake HYPOTHALAMUS NEUROPEPTIDE Signaling pathway HORMONE 
Identification and Expression Profile of a Neuropeptide LFRFamide-Like Gene During Different Stages of Gonadal Development in the Cephalopod Sepia pharaonis
《Journal of Ocean University of China》2024年第2期499-508,共10页QIU Jiayin SUN Lianlian LI Shuang ZHOU Xu CHI Changfeng ZHENG Libing 
supported by the National Natural Science Foundation of China(No.31872547);the Natural Science Foundation of Zhejiang Province,China(No.LY20 C190007);the Open Foundation from Marine Sciences in the First-Class Subjects of Zhejiang(No.OFMS004);the Excellent Postdoctoral Program of Jiangsu Province(No.314865).
Neuropeptides are widely distributed in vertebrates and invertebrates,regulating a variety of physiological activities in the organisms,such as metabolism,feeding and reproduction.In this study,to explore the function...
关键词：NEUROPEPTIDE LFRFamide-like CEPHALOPOD CUTTLEFISH Sepia pharaonis development REPRODUCTION 
Tumor microenvironment-activatable neuropeptide-drug conjugates enhanced tumor penetration and inhibition via multiple delivery pathways and calcium deposition
《Chinese Chemical Letters》2024年第4期292-297,共6页Yi Cao Xiaojiao Ge Yuanyuan Wei Lulu He Aiguo Wu Juan Li 
financially supported by the Key R&D Program of Zhejiang Province (No.2020C03110);the National Natural Science Foundation of China (Nos.T2222021, 32011530115,32025021);the Science&Technology Bureau of Ningbo City (Nos.2020Z094, 2021Z072);Excellent Member of Youth Innovation Promotion Association Foundation of CAS (No.Y2021079)。
Peptide-drug conjugates have achieved considerable development and application as a novel strategy for targeted delivery of anticancer drugs. Bioactive peptides induced calcium deposition can irreversibly assist inhib...
关键词：Neuropeptide-drug conjugate Tumor penetration Calcium deposition Tumor inhibition Triple-negative breast cancer 
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