A transition-metal-free strategy for the synthesis of tetrasubstituted furans is reported.Promoted by boron trifluo-ride diethyl etherate,the reaction of alkynyl sulfoxides with ynamides/ynol ethers proceeded via a ca...
supported by the National Natural Science Foundation of China(No.22108264).
Halogenation of N-cinnamylbenzamides and N-[(2H-chromen-3-yl)methyl]benzamides using electrophilic halogen source was reported.Various halogenated dihydro-1,3-oxazine derivatives(45 examples)were synthesized in high t...
Financial support from the National Natural Science Foundation of China (Nos. 22001151, 22171168, 22101159);Taishan Scholar Program of Shandong Province and Shandong Provincial Natural Science Foundation (Nos. ZR2019QB004, ZR2020QB019) is gratefully acknowledged。
A Cu-catalyzed chemoselective heterocyclization of o-cinnamoyl arylisocyanides with α-substituted tosylmethyl isocyanides is developed for the efficient synthesis benzopyrroloazepinones. An isocyanide insertion into ...
2-(Hydrazinecarbothioyl)-N-substituted hydrazinecarbothioamides react with 2,3,5,6-tetrachloro-1,4-benzoquinone in high yields in a novel fast and facile method to give 5-unsubstituted-1,3,4-thiadiazole-2-amine deri...
the financial support of the National Natural Science Foundation of China(No.20672050).
An alternative approach to synthesize pedamide, a key building block of pederin was described. Iodine-induced asymmetric heterocyclization was used as the key step to construct the skeleton, a tetrahydropyran ring wit...
A highly efficient synthesis of 2-amino-N-substituted-benzamides was performed by the condensation ofisatoic anhydride with several amines in solvent-free conditions under microwave irradiation. H-Y-zeolites induced h...