BIPHASIC

作品数：118被引量：249H指数：8
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相关机构：上海医科大学中南大学浙江大学医学院附属第二医院中国农业大学更多>>
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Integrating coaxial electrospinning and 3D printing technologies for the development of biphasic porous scaffolds enabling spatiotemporal control in tumor ablation and osteochondral regeneration
《Bioactive Materials》2024年第4期338-353,共16页Wenbao He Chunlin Li Shitong Zhao Zhendong Li Jing Wu Junjun Li Haichao Zhou Yunfeng Yang Yong Xu Huitang Xia 
supported by the National Natural Science Foundation of China(82302395 and 82001979);Natural Science Foundation of Shanghai(22YF1437400);Young Elite Scientists Sponsorship Program by CAST(2023QNRC001);Shandong Provincial Natural Science Foundation(Major Basic Research Program,ZR2019ZD38);Taishan Scholar Program of Shandong Province(To Huitang Xia,202211333);Natural Science Foundation of Shandong Province(ZR2020MH381);Academic Promotion Program of Shandong First Medical University(2019LJ005);Shandong First Medical University Culture Foundation(202201-09);Social Science Planning and Research Project of Shandong Province(21CTQJ08).
The osteochondral defects(OCDs)resulting from the treatment of giant cell tumors of bone(GCTB)often present two challenges for clinicians:tumor residue leading to local recurrence and non-healing of OCDs.Therefore,thi...
关键词：Spatiotemporal control Giant cell tumors of bone Shell-core structure Double-layered scaffold Osteochondral regeneration 
Synergistic stimulation of surface topography and biphasic electric current promotes muscle regeneration被引量：1
《Bioactive Materials》2022年第5期118-129,共12页Indong Jun Na Li Jaehee Shin Jaeho Park Young Jun Kim Hojeong Jeon Hyuk Choi Jae-Gu Cho Byoung Chan Choi Hyung-Seop Han Jae-Jun Song 
supported by a Korean National Research Foundation(NRF)grant funded by the Korea government(MSIT)(No.2017M3A9G1027929);supported by both the National Research Council of Science&Technology 424(NST)grant by the Korean government(MSIP)(CAP-17-01-KIST Europe);KIST project(2E31121).
Developing a universal culture platform that manipulates cell fate is one of the most important tasks in the investigation of the role of the cellular microenvironment.This study focuses on the application of topograp...
关键词：TOPOGRAPHY Electrical field stimulation Femtosecond laser Human myogenic precursor cell Cell therapy 
A hierarchical bilayer architecture for complex tissue regeneration被引量：4
《Bioactive Materials》2022年第4期93-106,共14页Min Yu Dan Luo Jing Qiao Jiusi Guo Danqing He Shanshan Jin Lin Tang Yu Wang Xin Shi Jing Mao Shengjie Cui Yu Fu Zixin Li Dawei Liu Ting Zhang Chi Zhang Zhou Li Yongsheng Zhou Yan Liu 
supported by the National Natural Science Foundations of China No.81871492(Y.L.),No.51902344(D.L.)and No.61875015(Z.L.);Ten-Thousand Talents Program QNBJ2019-2(Y.L.);Key R&D Plan of Ningxia Hui Autonomous Region No.2020BCG01001(Y.L.);National Key R&D Project from Minister of Science and Technology of China No.2016YFA0202703(D.L.).
Engineering a complete,physiologically functional,periodontal complex structure remains a great clinical challenge due to the highly hierarchical architecture of the periodontium and coordinated regulation of multiple...
关键词：Biomimetic design Biphasic scaffold Mineralized collagen Micropatterned arrays Periodontium regeneration 
Bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy被引量：13
《Bioactive Materials》2021年第8期2400-2411,共12页Beibei Yang Yating Dong Yifeng Shen Ailin Hou Guilan Quan Xin Pan Chuanbin Wu 
supported by the National Natural Science Foundation of China[grant No.81803466];the Research and Development Plan for Key Areas in Guangdong Province[grant No.2019B020204002];the National Science and Technology Major Program[grant No.2017zx09101001].
Hypertrophic scar(HS)is an undesirable skin abnormality following deep burns or operations.Although intralesional multi-injection with the suspension of triamcinolone acetonide(TA)and 5-fluorouracil(5-Fu)has exhibited...
关键词：Hypertrophic scar Bilayer microneedle Biphasic release Triamcinolone acetonide 5-FLUOROURACIL 
Biocompatibility of biphasic α,β-tricalcium phosphate ceramics in vitro被引量：2
《Bioactive Materials》2020年第2期423-427,共5页T.V.Safronova I.I.Selezneva S.A.Tikhonova A.S.Kiselev G.A.Davydova T.B.Shatalova D.S.Larionov J.V.Rau 
supported by the RFBR(grant No.18-29-11079)。
The biocompatibility of biphasicα,β-tricalcium phosphate ceramics,obtained by annealing a compact preform based onβ-tricalcium phosphate powder,was studied in vitro.It was found that within 10–30 days the adhesion...
关键词：Tricalcium phosphate CERAMICS Phase composition Dental pulp stem cells BIOCOMPATIBILITY 
Analysis of the in vitro degradation and the in vivo tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components--Guidance of the inflammatory response as basis for osteochondral regeneration被引量：3
《Bioactive Materials》2017年第4期208-223,共16页Mike Barbeck Tiziano Serra Patrick Booms Sanja Stojanovic Stevo Najman Elisabeth Engel Robert Sader Charles James Kirkpatrick Melba Navarro Shahram Ghanaati 
We thank the Spanish MINECO for supporting the project MAT2012-38793 and for funding MN through the Ramon y Cajal program and TS through the“Personal Tecnico de Apoyo”subprogram.
The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of osteochondral defects in vivo Focus...
关键词：Bioactive glass Polylactic acid(PLA) Bi-layer scaffold Multinucleated giant cells Bone substitute VASCULARIZATION Calcium phosphate glass 
RF magnetron-sputtered coatings deposited from biphasic calcium phosphate targets for biomedical implant applications被引量：3
《Bioactive Materials》2017年第3期170-176,共7页K.A.Prosolov K.S.Popova O.A.Belyavskaya J.V.Rau K.A.Gross A.Ubelis Yu.P.Sharkeev 
The study was conducted as part of the program of fundamental research of the state academies of sciences(PFR SAS)for 2015e2017 No.23.2.5;The project was supported by Marie Curie IRSES,project No.612691 of the EU Framework Programme-FP7;The authors thank A.Sainova,Yu.Glushko,M.Surmeneva,and Prof.M.Chaikina for support to the research and fruitful discussion of the results.
Bioactive calcium phosphate coatings were deposited by radio-frequency magnetron sputtering from biphasic targets of hydroxyapatite and tricalcium phosphate,sintered at different mass%ratios.According to Raman scatter...
关键词：RF-magnetron sputtering Biphasic hydroxyapatite-tricalcium phosphate targets Thin hydroxyapatite coatings Plasma coatings BIOCOMPATIBILITY 
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