ISOINDOLINONE

作品数：4被引量：3H指数：1
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相关领域：理学更多>>
相关期刊：《Chemical Research in Chinese Universities》《有机化学》《Chinese Journal of Chemistry》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金中国博士后科学基金更多>>
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Rh(Ⅲ)-Catalyzed Aminoalkylation of Alkenes with Diazo Compounds toward Functionalized Isoindolinones
《有机化学》2024年第11期3505-3517,共13页Yuying Liu Zhanwei Fu Chao Yang Mupeng Luo Shurong Ban Shouguo Wang 
山西省自然科学基金(No.202303021221131);山西省特色药物研制工程研究中心和深圳市科技创新委员会(Nos.JCYJ20210324101810028,JCYJ-20220818101601004,JCYJ20220818095801004)资助项目.
A[Cp*RhCl_(2)]_(2)-catalyzed intramolecular annulation reaction via aminoalkylation of alkenes with diazo compounds has been developed to construct highly-functionalized isoindolinones.This approach exhibits step econ...
关键词：aminoalkylation reaction annulation reaction ISOINDOLINONE Rh(Ⅲ)-catalysis diazo compounds 
Isocyanide-Based One-Pot Cascade Synthesis of 3-Acyl Isoindolinones
《Chinese Journal of Chemistry》2024年第3期259-263,共5页Jia Liu Yi-Ming Zhu Xiao-Ping Xu Shun-Jun Ji 
the National Natural Science Foundation of China(Nos.21772138 and 21672157);the Natural Science Foundation of Jiangsu Province(BK20221356);PAPD。
A series of 3-acyl-substituted isoindolinone derivatives were synthesized in a one-pot manner via the reaction of o-bromobenzaldehydes,isocyanides,and carboxylic acids in the presence of palladium catalyst and base. T...
关键词：One-pot reaction ISOCYANIDE Pd catalysis Rearrangement reaction ISOINDOLINONE 
BrΦnsted acid-promoted ‘on-water’ C(sp^3)-H functionalization fot the synthesis of isoindolinone/[1,2,4]triazolo[1,5-a]pyrimidine derivatives targeting the SKP2-CKS1 interaction被引量：1
《Chinese Chemical Letters》2020年第2期349-352,共4页Shuo Yuan Sixi Wang Min Zhao Danqing Zhang Jinjie Chen Jian-Xin Li Jingya Zhang Yihui Song Jinyi Wang Bin Yu Hongmin Liu 
supported by the National Natural Science Foundation of China(Nos.81773562 and 81703326);China Postdoctoral Science Foundation(Nos.2018M630840 and 2019T120641);Scientific Program of Henan Province(No.182102310123)。
The isoindolinone and biaryl scaffolds are prevalent in natural products and drug molecules,which have showed broad and interesting biological activities.The efficient construction of such hybridized molecules and bio...
关键词：ISOINDOLINONE [1 2 4]Triazolo[1 5-a]pyrimidine BIARYL scaffold C(sp^3)-H activation Molecular hybridization SKP2-CKS1 INTERACTION 
Synthesis of Novel 3-Aryl Isoindolinone Derivatives被引量：2
《Chemical Research in Chinese Universities》2013年第3期487-494,共8页HU Chen-ming ZHENG Lian-you PEI Ya-zhong BAI Xu 
Supported by the National Natural Science Foundation of China（No.81072526） and the Fund of the Department of Science and Technology of Jilin Province of China（No.20106039）.
A library of novel 3-aryl isoindolinone derivatives with aromatic amino acid derivative fragments was designed and synthesized. Two synthetic routes were employed to construct 3-aryl isoindolinone ring system for diff...
关键词：Molecular library 3-Aryl isoindolinone Aromatic amino acid derivative 
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