IMMUNOTOXICOLOGY

作品数：5被引量：23H指数：2
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Untoward immune effects of modern medication
《The Journal of Biomedical Research》2024年第1期17-23,共7页Daohong Chen 
Immune-related adverse events(irAEs)represent an increasingly concerning challenge in the assessment of biopharmaceutical products.In contrast to historically rare allergic reactions associated with small chemical dru...
关键词：IMMUNOTOXICOLOGY immune-related adverse events anti-drug antibody 
Biocompatibility and Immunotoxicology of the Preclinical Implantation of a Collagen-based Artificial Dermal Regeneration Matrix被引量：16
《Biomedical and Environmental Sciences》2018年第11期829-842,共14页WANG Wei ZHANG Lin SUN Lei SHE Zhen Ding TAN Rong Wei NIU Xu Feng 
supported by the National Natural Science Foundation of China [No.31470915];Shenzhen Science and Technology Project [No.JCYJ20170817140537062];the Fundamental Research Funds for the Central Universities [No.YWF-18-BJ-J-217];the 111 Project [No.B13003]
Objective Graft rejection, with the possibility of a violent immune response, may be severe and life threatening. Our aim was to thoroughly investigate the biocompatibility and immunotoxicology of collagen-based derma...
关键词：Collagen LYMPHOCYTES IMMUNOGENICITY Flow cytometry 
Immunotoxicity of bisphenol A to Carassius auratus lymphocytes and macrophages following in vitro exposure被引量：7
《Journal of Environmental Sciences》2007年第2期232-237,共6页YIN Da-qiang HU Shuang-qing GU Ying WEI Li LIU Shu-shen ZHANG Ai-qian 
Project supported by the National Natural Science Foundation of China (No. 20377022, 20237010);the National Basic Research Program (973) of China (No. 2002CB412307).
Bisphenol A （BPA） is the monomer component of polycarbonate plastics and classified as an endocrine disrupting chemical （EDC）. The reproductive toxicity of BPA has been extensively studied in mammals; however, rel...
关键词：bisphenol A IMMUNOTOXICOLOGY LYMPHOCYTE macrophage Carassius auratus 
Discussion on Improvement of Toxicological Pathology Study
《Science Foundation in China》2003年第1期31-34,共4页Ren Jin(Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, CAS, Shanghai 200031) 
Toxicological pathology plays a key role in drug safety assessment. To enhance the research level of toxicological pathology, the following stud-ies should be carried out urgently: setting up a standard operation proc...
关键词：drag safety assessment toxicological pathology immunotoxicology evaluation short-term replacement model highthroughput toxicology 
Harmonization of immunotoxicology study guidelines
《中国药理学与毒理学杂志》2002年第6期408-409,共2页NakaK 
Guidance for immunotoxicology studies has been intensively discussed.The European Medicnes Evaluation Agency published the draft guidance on immunotoxicity on December 16,1999 and finalized it on July 27,2000.In the m...
关键词：免疫毒理学 研究方法 指南 
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