supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA16030400);the National Basic Research Program of China(Grant No.2014CB964800);the National Natural Science Foundation of China(Grant Nos.31621004,31422038);the National Key Research and Development Program(Grant No.2017YFA0103803);CAS Key Projects(Grant No.QYZDY-SSWSMC022,QYZDB-SSW-SMC002).
Diploidy is the typical genomic mode in all mammals.Haploid stem cells are artificial cell lines experimentally derived in vitro in the form of different types of stem cells,which combine the characteristics of haploi...
supported by grants from the National Basic Research Program of China(2012CBA01300 to Q.Z.and 2014CB964800 to W.L.);the National Science Foundation of China(91319308 to Q.Z.).
Haploid pluripotent stem cells,such as haploid embryonic stem cells(haESCs),facilitate the genetic study of recessive traits.In vitro,fish haESCs maintain haploidy in both undifferentiated and differentiated states,bu...
Acknowledgements We thank James A. DOYLE, Peter K. ENDRESS, Timothy Y. JAMES, Paul KENRICK, and Michael J. WYNNE for helpful discussion, Christiane ANDERSON, Thomas E DUDA, Jr., James A. DOYLE, Evan ECONOMO, and Peter K. ENDRESS for help with literature search, and James A. DOYLE for carefully editing the manuscript. This work was supported by National Science Foundation grants DEB 0332298 and 0531689 to YLQ.
All sexually reproducing eukaryotes have a life cycle consisting of a haploid and a diploid phase, marked by meiosis and syngamy (fertilization). Each phase is adapted to certain environmental conditions. In land pl...