ANDROGENETIC

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Endorepellin和neurexin互作促进神经上皮细胞自噬并维持正常神经管发育
《Science Bulletin》2024年第14期2260-2272,共13页卢磊 白梅竹 郑煜芳 王修坤 陈仲中 彭瑞 Richard H.Finnell 赵同金 李承涛 吴波 雷云平 李劲松 王红艳 
supported by the National Key Research and Development Program of China(2021YFC2701100);the National Natural Science Foundation of China(81930036,32293230 and 8215008);the Commission for Science and Technology of Shanghai Municipality(20JC1418500 and 20ZR1404800);Project supported by Shanghai Municipal Science and Technology Major Project。
Heparan sulfate proteoglycan 2(HSPG2)gene encodes the matrix protein Perlecan,and genetic inactivation of this gene creates mice that are embryonic lethal with severe neural tube defects(NTDs).We discovered rare genet...
关键词：Neural tube defects Androgenetic haploid embryonic stem cells Basement membrane Neural stem cell AUTOPHAGY 
Nitric oxide synergizes minoxidil delivered by transdermal hyaluronic acid liposomes for multimodal androgenetic-alopecia therapy被引量：2
《Bioactive Materials》2024年第2期190-205,共16页Hui Xing Huanqi Peng Yuhui Yang Kai Lv Shihao Zhou Xiangjun Pan Jianjin Wang Yunfeng Hu Guowei Li Dong Ma 
financially supported by the National Natural Science Foundation of China(32171369 and 82102113);2023 cross-research project on basal research fund in central universities(21623410);the Jinan University-Honest Medical Joint Innovation Center(HX20220013);the Pre-study on transdermal technology and product development(ZX20220244)。
Androgenetic alopecia(AGA)is a common clinical condition,affecting over 200 million people globally each year.For decades,Minoxidil(Mi)tincture has been the primary treatment for this disease,but its low utilization r...
关键词：Nitric oxide Liposome Enhanced penetration Synergistic therapy Androgenetic alopecia 
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells被引量：3
《Protein & Cell》2022年第2期102-119,共18页Hongling Zhang Yuanyuan Li Yongjian Ma Chongping Lai Qian Yu Guangyong Shi Jinsong Li 
This study was supported by Genome Tagging Project and grants from the Chinese Academy of Sciences,the National Key Research and Development Program of China;the National Natural Science Foundation of China(2019YFA0109900,2020YFA0509000,XDB19010204,QYZDJ-SSW-SMC023,Facility-based Open Research Program,31821004,32030029,and 31730062).
The use of two inhibitors of Mek1/2 and Gsk3β(2i)promotes the generation of mouse diploid and haploid embryonic stem cells(ESCs)from the inner cell mass of biparental and uniparental blastocysts,respectively.However,...
关键词：paternal imprints androgenetic haploid ESCs DMRs semi-cloned mice alternative 2i 
Current advances in haploid stem cells被引量：2
《Protein & Cell》2020年第1期23-33,共11页Tongtong Cui Zhikun Li Qi Zhou Wei Li 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA16030400);the National Basic Research Program of China(Grant No.2014CB964800);the National Natural Science Foundation of China(Grant Nos.31621004,31422038);the National Key Research and Development Program(Grant No.2017YFA0103803);CAS Key Projects(Grant No.QYZDY-SSWSMC022,QYZDB-SSW-SMC002).
Diploidy is the typical genomic mode in all mammals.Haploid stem cells are artificial cell lines experimentally derived in vitro in the form of different types of stem cells,which combine the characteristics of haploi...
关键词：HAPLOIDY PARTHENOGENETIC ANDROGENETIC stem cells DIPLOIDIZATION functional genomics IMPRINTING 
The Effect of a Food Supplement and a Hair Lotion on the Progression of Androgenetic Alopecia
《Journal of Cosmetics, Dermatological Sciences and Applications》2019年第4期292-304,共13页Michael Bayer Manfred Gahrtz Werner Voss Gerrit Schlippe Thomas Whitfield 
Background: Progressing androgenetic alopecia (AGA), in both sexes, can result in severe distress. Treatments with the capacity to slow down the progression of AGA, or even to bring it to a halt, and at the same time ...
关键词：ANDROGENETIC ALOPECIA (AGA) Nutritional Supplement TOPICAL HAIR Treatment L-CARNITINE Zinc 
Concentrated Growth Factor from Autologous Platelet Promotes Hair Growth in Androgenetic Alopecia
《Journal of Biomedical Science and Engineering》2019年第3期201-211,共11页Poh-Ching Tan Yun Xie Wei Wu Peiqi Zhang Yiming Gao Kai Liu Shuangbai Zhou Qingfeng Li 
Studies have shown that platelet concentrates can induce the proliferation of the dermal papilla and the vascularization of the perifollicular tissue, as well as accelerate the telogen-to-anagen transition, thereby pr...
关键词：ANDROGENETIC ALOPECIA Concentrated Growth Factor 
Derivation of Haploid Neurons from Mouse Androgenetic Haploid Embryonic Stem Cells被引量：2
《Neuroscience Bulletin》2017年第3期361-364,共4页He Xu Chunmei Yue Ting Zhang Yuanyuan Li Ao Guo Jiaoyang Liao Gang Pei Jinsong Li Naihe Jing 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA01010201);the National Key Basic Research and Development Program of China(2015CB964500 and 2014CB964804);the National Natural Science Foundation of China(91219303,31430058,and 31401261)
Dear Editor,Haploid embryonic stem cells（ha ESCs）hold great potential for genetic screening and the analysis of recessive phenotypes.Several studies have recently reported the generation of mammalian ha ESCs through...
关键词：recessive haploid genomics screening embryonic manipulation pluripotent maintenance panel Mouse 
Derivation of androgenetic embryonic stem cells from m-carboxycinnamic acid bishydroxamide (CBHA) treated androgenetic embryos被引量：2
《Chinese Science Bulletin》2013年第23期2862-2868,共7页SHUAI Ling FENG ChunJing ZHANG HaiJiang GU Qi JIA YunDan WANG Liu ZHAO Xiao-Yang LIU ZhongHua ZHOU Qi 
supported by the National Key Basic Research Program of China(2012CB966500,2013CB-967100);the National Natural Science Foundation of China(31201112)
The androgenetic embyronic stem (aES) cells are useful models in studying the effects of imprinted genes on pluripotency maintaining and embryo development. The expression patterns of imprinted genes are significantly...
关键词：胚胎干细胞 雄性 ES细胞系 CAES 治疗 CB 印记基因 表达模式 
Identifying MicroRNA and mRNA Expression Profiles in Embryonic Stem Cells Derived from Parthenogenetic,Androgenetic and Fertilized Blastocysts被引量：1
《Journal of Genetics and Genomics》2013年第4期189-200,共12页Xiang-Shun Cui Xing-Hui Shen Shao-Chen Sun Sun-Wha Cho Young-Tae Heo Yong-Kook Kang Teruhiko Wakayama Nam-Hyung Kim 
supported by the grants from the NextGeneration BioGreen 21 Program(Nos.PJ009080 and PJ00909801);Rural Development Administration,Republic of Korea
MicroRNAs（miRNAs） are a class of highly conserved small non-coding RNA molecules that play a pivotal role in several cellular functions.In this study,miRNA and messenger RNA（mRNA） profiles were examined by Illumin...
关键词：Embryonic stem cell PARTHENOGENETIC ANDROGENETIC Fertilized MICROARRAY miRNA-mRNA network 
Haploid embryonic stem cells:an ideal tool for mammalian genetic analyses被引量：13
《Protein & Cell》2012年第11期806-810,共5页Linyu Shi Hui Yang Jinsong Li 
supported by grants from the Ministry of Science and Technology of China(No.2009CB941101 to J.L.);the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No.XDA01010403 to J.L.).
Identification of the function of all genes in the mammalian genome is critical in understanding basic mechanisms of biology.However,the diploidy of mammalian somatic cells has greatly hindered efforts to elucidate th...
关键词：haploid embryonic stem cells parthenogenetic embryos androgenetic embryos genetic screening DIPLOID genomic imprinting 
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