ACYLCARNITINES

作品数：4被引量：4H指数：1
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相关领域：医药卫生更多>>
相关期刊：《Chinese Medical Sciences Journal》《Science China Chemistry》《World Journal of Gastroenterology》《Journal of Pharmaceutical Analysis》更多>>
相关基金：国家自然科学基金更多>>
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Simultaneously quantifying hundreds of acylcarnitines in multiple biological matrices within ten minutes using ultrahigh-performance liquid-chromatography and tandem mass spectrometry被引量：1
《Journal of Pharmaceutical Analysis》2024年第1期140-148,共9页Jingxian Zhang Qinsheng Chen Lianglong Zhang Biru Shi Men Yu Qingxia Huang Huiru Tang 
financial supports from the National Key R&D Program of China(Grant Nos.:2022YFC3400700,2022YFA0806400,and 2020YFE0201600);Shanghai Municipal Science and Technology Major Project(Grant No.:2017SHZDZX01);the National Natural Science Foundation of China(Grant No.:31821002).
Acylcarnitines are metabolic intermediates of fatty acids and branched-chain amino acids having vital biofunctions and pathophysiological significances. Here, we developed a high-throughput method for quantifying hund...
关键词：ACYLCARNITINE UPLC-MS/MS Quantitative structure-retention relationship Molecular phenotype 
Predictive value of presepsin and acylcarnitines for severity and biliary drainage in acute cholangitis被引量：1
《World Journal of Gastroenterology》2023年第16期2502-2514,共13页Han-Yu Zhang Hong-Li Xiao Guo-Xing Wang Zhao-Qing Lu Miao-Rong Xie Chun-Sheng Li 
National Natural Science Foundation of China,No.81773931;Beijing Municipal Administration of Hospitals’ Youth Program,No.QML20170105;Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support "Yangfan" Project,No.ZYLX201804
BACKGROUND Bacteremia,which is a major cause of mortality in patients with acute cholangitis,induces hyperactive immune response and mitochondrial dysfunction.Presepsin is responsible for pathogen recognition by innat...
关键词：Acute cholangitis SEVERITY Biliary drainage Presepsin ACYLCARNITINES 
Association of altered serum acylcarnitine levels in early pregnancy and risk of gestational diabetes mellitus
《Science China Chemistry》2020年第1期126-134,共9页Hongzhi Zhao Han Li Yuanyuan Zheng Lin Zhu Jing Fang Li Xiang Shunqing Xu Yanqiu Zhou Hemi Luan Wei Xia Zongwei Cai 
supported by the National Natural Science Foundation of China(21437002);the General Research Fund(12319716)from Research Grants Council of Hong Kong
Gestational diabetes mellitus(GDM)is a high-prevalence disease and diagnosed in middle pregnancy.Acylcarnitines are a series of fatty acid esters of carnitine and play important roles in fatty acid and carbohydrate me...
关键词：ACYLCARNITINES gestational diabetes mellitus EPIDEMIOLOGY targeted metabolomics ultra-high performance liquid chromatography coupled with tandem mass spectrometry 
Liquid Chromatography-tandem Mass Spectrometry for Analysis of Acylcarnitines in Dried Blood Specimens Collected at Autopsy from Neonatal Intensive Care Unit被引量：2
《Chinese Medical Sciences Journal》2010年第2期109-114,共6页Wen-jun Tu Fang Dai Xin-yu Wang Ying Li James Jian Ho 
Objective To investigate the feasibility of analyzing acylcarnitine in dry filter-paper blood spots by liquid chromatography-tandem mass spectrometry(LC-MS/MS) which could be applied to detect inborn errors of metabol...
关键词：tandem mass spectrometry inborn errors of metabolism neonatal intensive care unit AUTOPSY 
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