ACYLCARNITINE

作品数：6被引量：9H指数：2
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相关领域：医药卫生更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Science China Chemistry》《Chinese Medical Journal》《World Journal of Meta-Analysis》更多>>
相关基金：国家自然科学基金更多>>
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Simultaneously quantifying hundreds of acylcarnitines in multiple biological matrices within ten minutes using ultrahigh-performance liquid-chromatography and tandem mass spectrometry被引量：1
《Journal of Pharmaceutical Analysis》2024年第1期140-148,共9页Jingxian Zhang Qinsheng Chen Lianglong Zhang Biru Shi Men Yu Qingxia Huang Huiru Tang 
financial supports from the National Key R&D Program of China(Grant Nos.:2022YFC3400700,2022YFA0806400,and 2020YFE0201600);Shanghai Municipal Science and Technology Major Project(Grant No.:2017SHZDZX01);the National Natural Science Foundation of China(Grant No.:31821002).
Acylcarnitines are metabolic intermediates of fatty acids and branched-chain amino acids having vital biofunctions and pathophysiological significances. Here, we developed a high-throughput method for quantifying hund...
关键词：ACYLCARNITINE UPLC-MS/MS Quantitative structure-retention relationship Molecular phenotype 
Metabolic and biological changes in children with obesity and diabetes
《World Journal of Meta-Analysis》2021年第2期153-163,共11页Shirou Matsumoto Tomomi Nakamura Fusa Nagamatsu Jun Kido Rieko Sakamoto Kimotoshi Nakamura 
The World Health Organization has stated that obesity in childhood is one of themost serious public health challenges of the 21st century. Overweightness andobesity in early childhood lead to a higher risk of overweig...
关键词：Children with obesity Diabetes mellitus Insulin resistance Amino acids ACYLCARNITINE Metabolomics 
Rhodiola crenulata extract decreases fatty acid oxidation and autophagy to ameliorate pulmonary arterial hypertension by targeting inhibiton of acylcarnitine in rats被引量：4
《Chinese Journal of Natural Medicines》2021年第2期120-133,共14页REN Huan-Huan NIU Zheng GUO Rui FU Min LI Hai-Ru ZHANG Xuan-Yu YAO Li 
the National Natural Science Foundation of China(No.81302764);the Science and Technology Grant for Excellent Talents of Harbin(No.2017RAXXJ-060).
Pulmonary arterial hypertension(PAH)is a devastating pulmonary circulation disease lacking high-efficiency therapeutics.The present study aims to decipher the therapeutic mechanism of Rhodiola crenulata,a well-known t...
关键词：Pulmonary arterial hypertension Rhodiola crenulata Target lipidomics Fatty acid oxidation AUTOPHAGY 
Association of altered serum acylcarnitine levels in early pregnancy and risk of gestational diabetes mellitus
《Science China Chemistry》2020年第1期126-134,共9页Hongzhi Zhao Han Li Yuanyuan Zheng Lin Zhu Jing Fang Li Xiang Shunqing Xu Yanqiu Zhou Hemi Luan Wei Xia Zongwei Cai 
supported by the National Natural Science Foundation of China(21437002);the General Research Fund(12319716)from Research Grants Council of Hong Kong
Gestational diabetes mellitus(GDM)is a high-prevalence disease and diagnosed in middle pregnancy.Acylcarnitines are a series of fatty acid esters of carnitine and play important roles in fatty acid and carbohydrate me...
关键词：ACYLCARNITINES gestational diabetes mellitus EPIDEMIOLOGY targeted metabolomics ultra-high performance liquid chromatography coupled with tandem mass spectrometry 
Acylcarnitine: Useful biomarker for early diagnosis of hepatocellular carcinoma in non-steatohepatitis patients
《World Journal of Gastrointestinal Oncology》2019年第10期887-897,共11页Hiroaki Takaya Tadashi Namisaki Mitsuteru Kitade Naotaka Shimozato Kosuke Kaji Yuki Tsuji Keisuke Nakanishi Ryuichi Noguchi Yukihisa Fujinaga Yasuhiko Sawada Soichiro Saikawa Shinya Sato Hideto Kawaratani Kei Moriya Takemi Akahane Hitoshi Yoshiji 
BACKGROUND Early diagnosis of hepatocellular carcinoma(HCC)is necessary to improve the prognosis of patients.However,the currently available tumor biomarkers are insufficient for the early detection of HCC.Acylcarniti...
关键词：ACYLCARNITINE Acetylcarnitine BIOMARKER HEPATOCELLULAR carcinoma Angiogenesis CARNITINE palmitoyltransferase 1 Oxidative stress 
Ethnic-specific splicing mutation of the carnitine-acylcarnitine translocase gene in a Chinese neonate presenting with sudden unexpected death被引量：4
《Chinese Medical Journal》2003年第7期1110-1112,共3页林青云 赖志刚 周镇邦 汤瑞芳 袁月冰 麦婉芳 陈恩和 
关键词：carnitine  acylcarnitine translocase deficiency SLC25A20 gene mutation 
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