MESODERM

作品数：15被引量：25H指数：4
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相关期刊：《Acta Biochimica et Biophysica Sinica》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《World Journal of Stem Cells》更多>>
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Zichong granules(资冲颗粒)promote differentiation of ovarian granulosa-like cells from human embryonic stem cells in vitro
《Journal of Traditional Chinese Medicine》2021年第2期203-211,共9页YAO Zouying WANG Jing LU Hua LI Limin ZHUO Tianxiu WAN Qian YIE Shangmian 
Supported by The National Basic Research Program of China:Study on the theory of"kidney governs reproduction"from the perspective of infertility(973 Plan,Grant Nos.2010CB530403 and 2010CB530400)。
OBJECTIVE:To investigate whether Zichong granules(资冲颗粒,ZCKL),a very effective herbal formula for treating infertility,have an impact on the differentiation of ovarian granulosa cells from human embryonic stem cell...
关键词：human embryonic stem cells INFERTILITY serum MESODERM OVARIAN granulosa cells Zichong granules 
Inducible overexpression of RUNX1b/c in human embryonic stem cells blocks early hematopoiesis from mesoderm被引量：4
《Journal of Molecular Cell Biology》2017年第4期262-273,共12页Bo Chen Jiawen Teng Hongwei Liu Xu Pan Ya Zhou Shu Huang Mowen Lai Guohui Bian Bin Mao Wencui Sun Qiongxiu Zhou Shengyong Yang Tatsutoshi Nakahata Feng Ma 
This work was supported by the National Program on Key Basic Research Project of China （973 Program; 2015CB964902）, the National Natural Science Foundation of China （NSFC; H81170466 and H81370597）, and the CAMS Initiatives for Innovative Medicine （2016-12M-1-018） awarded to F.M.
RUNXI is absolutely required for definitive hematopoiesis, but the function of RUNXlb/c, two isoforms of human RUNX1, is unclear. We established inducible RUNXlb/c-overexpressing human embryonic stem cell （hESC） lin...
关键词：RUNX1/AML1 HEMATOPOIESIS hemogenic endothelium MESODERM TGF-β signaling pathway HESC inducible expressionsystem 
IP3R-mediated Ca2＋ signals govern hematopoietic and cardiac divergence of Flk1＋ cells via the calcineurin-N FATc3-Etv2 pathway被引量：3
《Journal of Molecular Cell Biology》2017年第4期274-288,共15页Yi-Jie Wang Jijun Huang Wenqiang Liu Xiaochen Kou Huayuan Tang Hong Wang Xiujian Yu Shaorong Gao Kunfu Ouyang Huang-Tian Yang 
This study was supported by grants from the National Natural Science Foundation of China （31030050, 81520108004, and 81470422 to H.-T.Y.）, the Strategic Priority Research Program of Chinese Academy of Sciences （XDA01020204 to H.-T.Y.）, the National Basic Research Program of China （2014CB965100 to H.-T.Y.）, the National Science and Technology Major Project （2012ZX09501001 to H.-T.Y.）, and the Shenzhen Science, Technology and Innovation Committee OCYI 20160428154108239 to K.O.）.
Ca2＋ signals participate in various cellular processes with spatial and temporal dynamics, among which, inositol 1,4,5-trisphosphate receptors （IP3Rs）-mediated Ca2＋ signals are essential for early development. How...
关键词：IP3Rs Ca2＋ signals mesoderm specification hematopoietic and cardiac fate Etv2 
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