ANTIGEN

作品数：633被引量：1659H指数：17
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相关机构：华中科技大学郑州大学生物技术有限公司中国科学院上海生命科学研究院更多>>
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Mycobacterial antigen Ag85B restrains Hodgkin lymphoma tumor growth by inhibiting autophagy
《Oncology Research》2025年第5期1173-1187,共15页YONGFENG CHENG YIPING SHEN YUNFEI ZHANG HAILIQIGULI NURIDING XUEMEI WANG CHUNYAN FAN GULIBAHA MAIMAITI YU LIU YINGBIN YUE DANLU LI MEI YAN 
supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region of China(grant number 2022D01C739);the National Natural Science Foundation of China(grant numbers 82160031,82071276);the Key Research and Development Program of Xinjiang Uyghur Autonomous Region of China(grant number 2024B03038-1).
Background:The growth of the B-cell lymphoma subtype,Hodgkin lymphoma(HL),is associated with increased autophagy.A mycobacterial antigen,Ag85,has been reported to inhibit cell autophagy under a variety of conditions.W...
关键词：Hodgkin disease Mycobacterial antigen AUTOPHAGY Protein kinase B Mitogen-activated protein kinases 
Retrospective analysis of preoperative tumor marker levels in rectal cancer patients: Implications for diagnosis
《World Journal of Gastrointestinal Surgery》2025年第3期221-228,共8页Ming Li Da-Hao Yuan Zhi Yang Teng-Xiang Lu Lei Zhang 
BACKGROUND Early detection of rectal cancer poses significant challenges.Current diagnostic methods,including colonoscopy,imaging techniques,and fecal tests,have limitations such as invasiveness,cost,and varying sensi...
关键词：Rectal cancer Tumor markers Carcinoembryonic antigen Cancer antigen 19-9 Cancer antigen 72-4 Fecal occult blood test DIAGNOSIS 
A recombinant fragment antigen-binding(Fab)of trastuzumab displays low cytotoxic profile in adult human cardiomyocytes:first evidence and the key implication of FcγRIIA receptor
《Acta Pharmacologica Sinica》2025年第3期618-631,共14页Anna De Bartolo Naomi Romeo Alessandro Marrone Vittoria Rago Maria Concetta Granieri Maria Luigia Vommaro Arianna Cupelli Maria Carmela Cerra Cesare Indiveri Raffaele Ronca Maria Cantile Riccardo Sanna Carmine Rocca Tommaso Angelone 
supported by“SI.F.I.PA.CRO.DE.–Sviluppo e industrializzazione farmaci innovativi per terapia molecolare personalizzata PA.CRO.DE”(PON ARS01_00568).
Fragment crystallizable gamma receptors(FcγRs)mediate various cellular responses with significant cardiovascular implications.They contribute to the anticancer activity of trastuzumab(TRZ),a recombinant humanized mon...
关键词：cardiac complications TRASTUZUMAB rFab-HER2 Fc region FcyRIIA HER2 
Zoledronate-loaded aluminum salt nanovaccines amplify cellular immune response by enhancing cross-presentation
《Nano Research》2025年第1期559-571,共13页Chunting He Penghui He Xue Tang Shuting Bai Ming Qin Yunting Zhang Zhaofei Guo Guangsheng Du Xun Sun 
supported by the National Natural Science Foundation of China(Nos.82320108020 and 81925036);the National Key Research and Development Program of China(No.2023YFC2307700);111 project(No.B18035);the Fundamental Research Funds for the Central Universities。
Being a Th2 stimulator,classic aluminum salt-based adjuvants only stimulate weak cellular immune responses that are required for vaccination against intracellular viruses or cancerous cells.As a thirdgeneration bispho...
关键词：zoledronate(ZOL) mevalonate pathway antigen cross-presentation cellular immune responses 
FOXO1 or not FOXO1:that is the question
《Cancer Communications》2025年第1期43-45,共3页Maude Marchais Marianne Mangeney 
supported by INSERM,CNRS,La Ligue Nationale Contre le Cancer(RS20/75-99,Inserm Transfert[CoPOC MAT-PI-171185-A-01]);Bristol Myers Squibb Foundation for Research in Immuno-Oncology;Bristol-Myers Squibb,Grant/Award Number:260403;Ligue Contre le Cancer。
Two groundbreaking articles in Nature by Evan W.Weber[1]and Philippe Darcy teams[2]revealed that overexpressing the transcription factor Forkhead Box O1(FOXO1)boosts Chimeric Antigen Receptor-T(CAR-T)cell antitumor ac...
关键词：FOXO1 ANTIGEN WEBER 
STING-activating dendritic cell-targeted nanovaccines that evoke potent antigen cross-presentation for cancer immunotherapy被引量：1
《Bioactive Materials》2024年第12期345-365,共21页Nguyen Thi Nguyen Xuan Thien Le Woo Tak Lee Yong Taik Lim Kyung Taek Oh Eun Seong Lee Han-Gon Choi Yu Seok Youn 
supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT,No.RS-2024-00352440 and No.NRF-2019R1A5A2027340).
Recently,nanovaccine-based immunotherapy has been robustly investigated due to its potential in governing the immune response and generating long-term protective immunity.However,the presentation of a tumor peptide-ma...
关键词：DC-based nanovaccines Artificial antigen-presenting cells Type 1 conventional dendritic cells STING pathway activation Antigen cross-presentation 
Impact of antisperm antibodies on sperm functions and fertility in livestock:A narrative review
《Asian pacific Journal of Reproduction》2024年第6期251-260,共10页Channareddi Kuntareddi Kamaraj Elango Pradeep Nag Arumugam Kumaresan 
Spermatozoa are recognized as foreign cells by both male and female immune systems,leading to the production of antisperm antibodies(ASAs)when sperm are exposed to immune system due to a breach in the mucosal barrier....
关键词：SUBFERTILITY ANTIGEN Sperm quality Male fertility Immunological infertility FERTILIZATION 
Renshen(Radix Ginseng) polysaccharide promotes repair of the mice intestinal mucosa through regulatory mechanisms based on polyamine and human antigen R
《Journal of Traditional Chinese Medicine》2024年第6期1118-1126,共9页WANG Guanyu DAI Xingzhen LIU Yiting ZHU Zeming HU Ling LI Ruliu 
National Natural Science Foundation of China:Study on the Effect of Supplementing Qi and Invigorating the Spleen on the Migration of Small Intestinal Epithelial Cells through the Regulation of Polyamines and Calcium Ions (No. 81673940);First-class Discipline Construction Major Project of Guangzhou University of Chinese Medicine,Guangzhou University of Chinese Medicine Planning (2020) No. 62:based on the Viscous Characteristics of Dampness and Pathogenic Factors in Lingnan,this Paper Studied the Differential Characteristics of the Syndrome of Deficiency of Spleen and Stomach Disease and the Intervention Mechanism of Lingnan Traditional Chinese Medicine for Mucosal Damage Repair。
OBJECTIVE: To investigate the mechanism and effect of Renshen(Radix Ginseng) polysaccharide on the migration of intestinal epithelial cell line 6(IEC-6), as well as the repair mechanism of Renshen(Radix Ginseng) polys...
关键词：Renshen(Radix Ginseng) polysaccharides human antigen R post-transcriptional regulation cell movement intestinal mucosal damage repair 
Magnetic Field Emulations of Small Inhibitor RNA: Effects on Implanted GL261 Tumors in C57BL/6 Immune Competent Mice
《Open Journal of Biophysics》2024年第4期339-354,共16页Xavier A. Figueroa Gabriel Vogeli B. Michael Butters 
EMulate Therapeutics has developed a system for emulating the effects of solvated molecules via their magnetic field recordings. Recordings of magnetic field emissions of select small inhibitor RNAs (siRNAs;murine tar...
关键词：Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) Programmed Cell Death Protein 1 (PD-1) Electromagnetic Field Emulation Cancer Tumor Murine Glioblastoma Multiforme (GBM) 
Study on the Technical Parameters for Estimating HIV-1 Incidence by Using a Recombinant Antigen-based Capture Enzyme Immunoassay—China
《China CDC weekly》2024年第48期1278-1282,共5页Wenli Liang Jibao Wang Hongxia Yan Xinhui Zhang Dorjiwangmo Dongmin Li Xing Duan Hao Wu Yinyin Wang Li Bai Jian Sun Mengjie Han Yikui Wang Bin Su Min Wang Tashibazong Wenge Xing Cui Zhang Ruijuan Qiao Maofeng Qiu 
Supported by the National Science and Technology Major Project of the 13th Five-year Plan(grants 2017ZX10201101-002-003 and 2018ZX10721102-003-002)。
Introduction:A novel recombinant antigen-based capture enzyme immunoassay(RAg-CEIA)was optimized and used to determine technical parameters for estimating human immunodeficiency virus type 1(HIV-1)incidence in China.M...
关键词：ANTIGEN EXCEEDING false 
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