CHOLATE

作品数：9被引量：11H指数：3
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相关领域：医药卫生理学更多>>
相关作者：冯德杰高雪军朱莉萍王秀珍更多>>
相关机构：北京大学兰州生物制品研究所美国德州大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《Journal of Rare Earths》《Open Journal of Physical Chemistry》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金更多>>
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Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine,liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin被引量：3
《Acta Pharmaceutica Sinica B》2023年第1期227-245,共19页Shijin Hong Shuai Li Xiaoyan Meng Ping Li Xun Wang Mengxiang Su Xiaodong Liu Li Liu 
supported by the National Natural Science Foundation of China(Nos.82173884,81872930,82073922 and 81872833);the“Double First-Class”university project(No.CPU2018GY22,China)。
Body is equipped with organic cation transporters(OCTs).These OCTs mediate drug transport and are also involved in some disease process.We aimed to investigate whether liver failure alters intestinal,hepatic and renal...
关键词：BILIRUBIN Chenodeoxycholic acid Farnesoid X receptor Liver failure Organic cation transporters Bile duct ligation Physiologically based pharmacokinetic model 
Diabetes downregulates peptide transporter 1 in the rat jejunum:possible involvement of cholate-induced FXR activation被引量：3
《Acta Pharmacologica Sinica》2020年第11期1465-1475,共11页Li-min Liang Jun-jie Zhou Feng Xu Pei-hua Liu Lan Qin Li Liu Xiao-dong Liu 
supported by the National Natural Science Foundation of China(Nos.81872930,81673505 and 81573490);the"Double First-Class"university project(No.CPU2018GY22).
Peptide transporter 1(PepT1),highly expressed on the apical membrane of enterocytes,is involved in energy balance and mediates intestinal absorption of peptidomimetic drugs.In this study,we investigated whether and ho...
关键词：peptide tran sporter 1 DIABETES farnesoid X receptor Caco-2 cells in testine che no deoxycholic acid 
Bile salt induced solubilization of methylene blue: Study on methylene blue fluorescence properties and molecular mechanics calculation被引量：2
《Journal of Pharmaceutical Analysis》2017年第1期71-75,共5页Susithra Selvam Ivy Sarkar 
DST–SERB, India (SB/FT/CS-032/2012) for the financial support
Methylene blue(MB) is a hydrophobic drug molecule, having importance both as a staining reagent and pharmaceutical agent. MB is strongly fluorescent, with an emission peak at 686 nm(λ_(ex)665 nm). In the study,the po...
关键词：METHYLENE BLUE SODIUM DEOXYCHOLATE SODIUM CHOLATE Absorption Fluorescence spectroscopy Molecular mechanics 
Determination of the Stabilization Time of the Solution-Air Interface for Aggregates Formed by NaC in Mixtures with SDS and PEO, Investigated by Dynamic Surface Tension Measurements
《Soft》2014年第1期1-10,共10页Grasiele Raupp Arlindo C. Felippe Tiago Elias Allievi Frizon Luciano da Silva Marcos Marques da Silva Paula Alexandre G. Dal-Bó 
The properties of mixtures of poly (ethylene oxide) (PEO) and mixed micelles formed from sodium cholate (NaC) and sodium dodecyl sulfate (SDS) in tris/HCl buffered solutions at pH 9.00 were investigated by measuring t...
关键词：Poly (Ethylene Oxide) Micelles SODIUM CHOLATE SODIUM Dodecyl SULFATE 
Methyl Cholate and Resorcinarene New Carriers for the Recovery of Cr(Ⅲ) Ions by Supported Liquid Membranes (SLM)s
《Open Journal of Physical Chemistry》2013年第3期103-114,共12页Abdelkhalek Benjjar Tarik Eljaddi Oussama Kamal Laurent Lebrun Miloudi Hlaibi 
All authors thank the Agence Universitaire de la Fran-cophonie(AUF)for financial support(PCSI 59113PS 014);Professor Jean-François Verchère from the University of Rouen(France)for his advice,fruitful dis-cussions,strong encouragement and exemplary coopera-tion.
The technique of supported liquid membranes was used to achieve the facilitated transport of Cr(III) ions, using tow amphiphilic carriers, the methyl cholate and resorcinarene. For prepared SLMs, toluene as organic ph...
关键词：Supported Liquid Membrane Facilitated Transport Methyl Cholate Resorcinarene Permeability Flux Association Constant Diffusion Coefficient 
Diagnosis in bile acid-CoA:Amino acid N-acyltransferase deficiency被引量：3
《World Journal of Gastroenterology》2012年第25期3322-3326,共5页Nedim Hadzi Laura N Bull Peter T Clayton AS Knisely 
Supported by Great Ormond Street Hospital Children’s Charity, to Clayton PT;National Institutes of Health;Grant R01 DK58214, to Bull LN
Cholate-CoA ligase （,EEL） and bile acid-CoA： amino acid N-acyltransferase （BAAT） sequentially mediate bile-acid amidation. Defects can cause intrahepatic cholestasis. Distinction has required gene sequencing. We ...
关键词：AMIDATION Bile acid-CoA Amino acid N-ac- yltransferase Cholate-CoA ligase  Cholestasis Conjuga-tion Electrospray ionisation-mass spectroscopy Immu-nohistochemistry Liver Neonatal hepatitis SIC27A5 Transmission electron microscopy 
Effect of the ulcerogenic agents ethanol, acetylsalicylic acid and taurocholate on actin cytoskeleton and cell motility in cultured rat gastric mucosal cells
《World Journal of Gastroenterology》2005年第26期4032-4039,共8页Siamak Bidel Harri Mustonen Giti Khalighi-Sikaroudi Eero Lehtonen Pauli Puolakkainen Tuula Kiviluoto Eero Kivilaakso 
Supported by the Grants from Antti and Jenny Wihuri Foundation and Research Foundation of Helsinki University Central Hospital, TYH4228
AIM: To assess the effects of ulcerogenic agents on actin cytoskeleton and cell motility and the contribution of oxidative stress.METHODS: Rat gastric mucosal cell monolayers were cultured on coverslips. The cells wer...
关键词：Gastric mucosa Ethyl alcohol TAUROCHOLATE ASPIRIN ACTIN 
Phenomena of Periodic Precipitaion in Rare Earth-Cholate Diffusion Systems被引量：1
《Journal of Rare Earths》1999年第2期2-4,共3页Xie Datao, Wang Libo, Wu Jinguang, Xu Guangxian (State Key Laboratory of Rare Earth Materials Chemistry and Applications, Peking University, Beijing 100871, China) 
The precipitate patterns were studied in rare earthcholate diffusion systems. The corresponding precipitates were characterized by Forie Transformed Infrared(FTIR) and Extended XRay Absorption Fine Structure(EXAFS) sp...
关键词：Rare earths Periodic precipitation CHOLATE 
Effects of Cholate on the Stability of Bacteriorhodopsin in Alkaline Solution
《Tsinghua Science and Technology》1997年第1期74-77,共4页王居硕 许强 赵南明 
The effects of cholate on the structure of bacteriorhodopsin (bR) in the purple membrane and the effects of alkali on native and cholate treated bR were studied using absorption spectra, fluorescence spectra and CD s...
关键词：bacteriorhodopsin (bR) purple membrane CHOLATE absorption spectra fluorescence spectra CD spectra 
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