This work was supported by the Stanford Bio-X Interdisciplinary Initiatives Seed Grants Program(IIP)[R10-14];Stanford Center for Cancer Nanotechnology Excellence for Translational Diagnostics(CCNE-TD)seed grant,Stanford Beckman Center Technology Development Seed Grants,National Cancer Institute of the National Institutes of Health(Award#R21CA261643 and RO1CA2515143),Stand Up to Cancer and Cancer Research Uk.
Patient-derived tumor organoids have emerged as promising models for predicting personalized drug responses in cancer therapy,but they typically lack immune components.Preserving the in vivo association between tumor ...
National Natural Science Foundation of China(82271651)。
Objective:To develop a clinically applicable tool for predicting clinical pregnancy,providing individualized patient counseling,and helping couples with non-obstructive azoospermia(NOA)decide whether to use fresh or c...
This study was supported by the Natural Science Foundation of Beijing Municipality(No.7194332 and No.7222208).
To investigate the factors affecting the sperm retrieval rate of microdissection testicular sperm extraction(micro-TESE)in patients with nonmosaic Klinefelter syndrome(KS),64 patients with nonmosaic KS who underwent m...
For men with severe oligozoospermia, sperm cryopreservation can preserve surgically obtained sperm. How to cryopreserve single sperm in men is still a hot topic in assisted reproduction technology. Aim to analyze the ...
supported by a grant from the Peking University Clinical Medicine Youth Special Fund(PKU20222LCXQ042).
Microdissection testicular sperm extraction(micro-TESE)is widely used to treat nonobstructive azoospermia.However,a good prediction model is required to anticipate a successful sperm retrieval rate before performing m...
supported by the National Natural Science Foundation of China(No.82171590,82171597,and 82001530);Clinical Research Innovation Plan of Shanghai General Hospital(KD007-ly01,and CTCCR-C04)。
Stepwise mini-incision microdissection testicular sperm extraction(mTESE)is a procedure that attempts to minimize testicular damage.However,the mini-incision approach may vary in patients with different etiologies.Her...
This study aims to explore the factors influencing the success rate of the microdissection testicular sperm extraction(Micro-TESE)in patients with nonobstructive azoospermia(NOA)and cryptorchidism.Clinical data of 162...
Dear Editor,Microdissection testicular sperm extraction(micro-TESE)is an optimal sperm extraction method for men with nonobstructive azoospermia(NOA).1 According to a recent systematic review by Corona et al.,2 the sp...
This retrospective study demonstrates the clinical outcomes of patients with nonmosaic Klinefelter's syndrome(KS)who underwent preimplantation genetic testing(PGT)with frozen-thawed testicular spermatozoa.Microdissect...
Sperm identification and selection is an essential task when processing human testicular samples for in vitro fertilization.Locating and identifying sperm cell(s)in human testicular biopsy samples is labor intensive a...