CEFOTETAN

作品数:3被引量:2H指数:1
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相关领域:医药卫生更多>>
相关期刊:《Acta Biochimica et Biophysica Sinica》《Chemical Research in Chinese Universities》更多>>
相关基金:国家自然科学基金福建省自然科学基金更多>>
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Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway
《Acta Biochimica et Biophysica Sinica》2022年第12期1917-1923,共7页Chenyun Guo Hao Xu Yu Zhou Zhihua Wu Bin Jiang Hanyu Chen Donghai Lin 
supported by the grants from the Natural Science Foundation of China(No.31470034);the Natural Science Foundation of Fujian Province(No.2020J01022);the Joint Funds for the Innovation of Science and Technology,Fujian Province(No.2018Y9100);the Open Research Fund of State Key Laboratory of Cellular Stress Biology,Xiamen University(No.SKLCSB2020KF002).
Cefotetan is widely used to treat bacterial infections in the clinic owing to its broad spectrum of antibacterial activity.In the present study,we demonstrate that cefotetan can bind to the conserved ligand-binding po...
关键词:CEFOTETAN ERK phosphorylation hRKIP NMR BLI 
LC-MS/MS Method for the Quantitation of Cefotetan in Human Plasma and Its Application to Pharmacokinetic Study
《Chemical Research in Chinese Universities》2014年第6期900-904,共5页SHI Meiyun YIN Lei CAI Lanlan WANG Can LIU Xidong ZHAO Sen SUN Yantong FAWCETT J. Paul ZHAO Limei YANG Yan GU Jingkai 
Supported by the National Natural Science Foundation of China(Nos.81430087, 81473142, 81102383) and the Prej ect of China Equipment and Education Resources System(CERS)(No.CERS-1-70).
A rapid and sensitive liquid chromatography-tandem mass spectrometry(LC-MS/MS) method for the de- termination of cefotetan in human plasma was developed and validated. After the protein precipitation of sample with ...
关键词:CEFOTETAN Liquid chromatography-tandem mass spectrometry(LC-MS/MS) PHARMACOKINETICS HUMANPLASMA 
A Simple and Sensitive Liquid Chromatographic Technique for the Determination of Cefotetan Disodium in Human Plasma and Its Application in a Pharmacokinetic Study被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2012年第5期779-784,共6页刘亚妮 黄建耿 刘金梅 马林 吕永宁 师少军 
supported by a grant of the Guangzhou Boji Clinical Research Center of New Drugs,Guangzhou,Guangdong,China
A simple and sensitive liquid chromatographic method was developed for quantification of cefotetan disodium (CTT),a semi-synthetic cephamycin antibiotic,in human plasma.CTT and the internal standard chloramphenicol we...
关键词:cefotetan disodium liquid chromatography human plasma PHARMACOKINETICS 
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