COFACTOR

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Creation of cytochrome P450 catalysis depending on a non-natural cofactor for fatty acid hydroxylation被引量：1
《Journal of Energy Chemistry》2023年第4期31-36,共6页Qing Li Xiaojia Guo Xueying Wang Junting Wang Li Wan Haizhao Xue Zongbao K.Zhao 
supported by the National Key R&D Program of China(2019YFA0904900);the National Natural Science Foundation of China(21877112,21837002,21721004)。
Cytochrome P450 enzymes catalyze diverse oxidative transformations at the expense of reduced nicotinamide adenine dinucleotide phosphate(NADPH),however,their applications remain limited largely because NADPH is cost-p...
关键词：Biocatalysis Cytochrome P450 Directed evolution Fatty acid hydroxylation Non-natural cofactor Synthetic biology 
Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH： A mini review被引量：4
《Frontiers of Chemical Science and Engineering》2017年第1期66-71,共6页Jongmoon Park Yunnam Choi 
Cyanobacteria can produce useful renewable fuels and high-value chemicals using sunlight and atmo- spheric carbon dioxide by photosynthesis. Genetic manip- ulation has increased the variety of chemicals that cyanobact...
关键词：NADH-dependent enzyme NADPH-depen-dent enzyme TRANSHYDROGENASE site-directed mutagenesis enzyme engineering 
Characterization of 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase(MenB) in phylloquinone biosynthesis of Synechocystis sp.PCC 6803
《Science China Chemistry》2012年第1期98-105,共8页SONG HaiGang GUO ZhiHong 
supported by GRF601209 from the Research Grants Council of the HKSAR government
The gene product Sll1127 is a predicted 1,4-dihydroxy-2-naphthoyl-CoA synthase catalyzing an intramolecular Claisen condensation in the phylloquinone biosynthesis of the cyanobacterium Synechocystis sp.PCC 6803.This p...
关键词：DHNA-CoA synthase bicarbonate cofactor PHYLLOQUINONE MENAQUINONE BIOSYNTHESIS 
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