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MENAQUINONE: 作品数：11被引量：7H指数：1; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：徐红张启元张汝波李银科屈正旺更多>>; 相关机构：沈阳药科大学玉溪师范学院中国科学院温州医科大学更多>>; 相关期刊：《沈阳药科大学学报》《Science Bulletin》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《理化检验（化学分册）》更多>>; 相关基金：国家自然科学基金辽宁省自然科学基金国家重点基础研究发展计划更多>>

Accelerating the menaquinone‑7 production in Bacillus amyloliquefaciens by optimization of the biosynthetic pathway and medium components被引量：1: 《Systems Microbiology and Biomanufacturing》2023年第4期776-791,共16页Chang‑Long Li Meng Li Wei‑Guo Zhang Jian‑Zhong Xu; This work was supported by the National Natural Science Foundation of China(no.32271534);the National Key Research and Development Program of China(2021YFC2100900);the Top-Notch Academic Programs Project of Jiangsu Higher Education Institutions,the 111 project(Grant number 111-2-06).; Menaquinone-7(MK-7)has an important role in preventing diseases such as cardiovascular disease and osteoporosis.In this study,a combination strategy of strain improvement and medium optimization is investigated to inc...; 关键词：Bacillus amyloliquefaciens Menaquinone-7 ARTP mutagenesis system Protoplast fusion Medium optimization

Menaquinone-7对大鼠糖皮质激素性骨质疏松的抑制作用: 《沈阳药科大学学报》2021年第3期279-283,共5页李飞陈侠徐峰; 辽宁省自然科学基金指导计划(201602713)。; 目的考察menaquinone-7(MK-7)对糖皮质激素致大鼠骨质疏松的作用。方法采用糖皮质激素诱导大鼠骨质疏松,测定血清碱性磷酸酶(alkaline phosphatase,ALP)水平评定造模结果,将造模成功的大鼠随机分组给药。检测骨形态、生物力学指标及相...; 关键词：Menaquinone-7 骨质疏松骨钙素

Menaquinone-7对大鼠血管钙化的抑制作用被引量：1: 《沈阳医学院学报》2020年第2期114-117,134,共5页李飞徐峰陈侠; 辽宁省自然科学基金指导计划(No.201602713)。; 目的:考察Menaquinone-7 (MK-7)对糖皮质激素诱导大鼠血管钙沉积的作用及机制。方法:大鼠连续注射地塞米松6周后,测定血清碱性磷酸酶(alkaline phosphatase,ALP)水平评定造模结果,将造模成功的大鼠随机分组给药。采用Von Kossa染色法检...; 关键词：Menaquinone-7 血管钙化血管生长停滞特异性基因产物6

超高效液相色谱法测定Menaquinone-7原料药主成分及有关物质被引量：1: 《理化检验（化学分册）》2017年第12期1381-1385,共5页宋怡孔凡建李银科王泉; 国家自然科学基金(21562044); Menaquinone-7原料药在避光条件下经无水乙醇超声溶解后,采用Agilent Eclipse plus C_(18)色谱柱(2.1mm×50mm,1.8μm)分离主成分及有关物质,以甲醇-水(98+2)混合液为流动相,分别在波长246,270nm处测定主成分及有关物质。Menaquinone-7...; 关键词：超高效液相色谱法 Menaquinone-7 主成分有关物质

Menaquinone-7 production from maize meal hydrolysate by Bacillus isolates with diphenylamine and analogue resistance被引量：2: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第6期462-473,共12页Jian-zhong XU Wei-guo ZHANG; supported by the Natural Science Foundation of Jiangsu Province(No.BK20150149),China; A menaquinone-7（MK-7） high-producing strain needs to be isolated to increase MK-7 production, in order to meet a requirement of MK-7 given the low MK-7 content in food products. This article focuses on developing MK...; 关键词：Menaquinone-7 Bacillus amyloliquefaciens Analog resistance Diphenylamine resistance Maize meal hydrolysate

Effects of Vitamin K-1 and Menaquinone-7 on Vascular Function and Blood Pressure in Warfarin-Induced Calcification-Model in Rats: 《Pharmacology & Pharmacy》2014年第12期1095-1105,共11页Aino Siltari Niko Wickholm Anne SKivimaki Kaisa Olli Krista Salli Kirsti Tiihonen Riitta Korpela Heikki Vapaatalo; DuPont Nutrition ; Health, Finska Läkaresalskapet; Finnish Clinical Chemistry Foundation; Given that vascular calcification is inversely correlated with the clinical intake of menaquinone, a rat model of warfarin-induced calcification may be useful for testing menaquinone and vitamin K-1 potential effects ...; 关键词：Vascular Calcification Vitamin K-1 Menaquinone-7 Blood Pressure Vascular Function

Menaquinone (Vitamin K2) Enhancement of <i>Staphylococcus aureus</i>Biofilm Formation被引量：1: 《Journal of Biosciences and Medicines》2014年第1期26-32,共7页Derek T. Kirby Joyce M. Savage Balbina J. Plotkin; During infection, Staphylococcus aureus is exposed to exogenous menaquinone which is essential for the human blood clotting cascade. The effect of exogenous menaquinone on S. aureus phenotypic expression is not known....; 关键词：QUORUM S. aureus MENAQUINONE FIBRONECTIN Biofilm Capsule Plastic Adherence CAROTENOID

Semi-Automated Method for Multi-Tasking Measurement of Microbial Growth, Capsule, and Biofilm Formation: 《Advances in Microbiology》2012年第4期623-628,共6页Derek T. Kirby Craigory J. Raino Samuel F. Rabor Jr. Cassandra J. Wasson Balbina J. Plotkin; The majority of bacterial infections involve the formation of biofilms. Biofilm formation is nutrient and growth dependent. Determination of the effects of nutrients on exopolysaccharide production and bacterial growt...; 关键词：Biofilm STAPHYLOCOCCUS AUREUS ESCHERICHIA COLI Quorum-Signaling Compounds MENAQUINONE Insulin Growth

Characterization of 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase(MenB) in phylloquinone biosynthesis of Synechocystis sp.PCC 6803: 《Science China Chemistry》2012年第1期98-105,共8页SONG HaiGang GUO ZhiHong; supported by GRF601209 from the Research Grants Council of the HKSAR government; The gene product Sll1127 is a predicted 1,4-dihydroxy-2-naphthoyl-CoA synthase catalyzing an intramolecular Claisen condensation in the phylloquinone biosynthesis of the cyanobacterium Synechocystis sp.PCC 6803.This p...; 关键词：DHNA-CoA synthase bicarbonate cofactor PHYLLOQUINONE MENAQUINONE BIOSYNTHESIS

Theoretical Studies on the Mechanism of the Proton-transfer-coupled Electron Transfer Reactions Between Menaquinone Q_A and Ubiquinone Q_B in the Bacterial Photosynthetic Reaction Center of Rhodopseudomona viridis被引量：1: 《Acta Botanica Sinica》2002年第12期1409-1417,共9页马淑华徐红张汝波屈正旺张兴康张启元; 国家自然科学重大基金 (3 9890 3 90 ) ;国家基础研究发展规划项目 (G19980 10 10 0 )~~; The mechanism of the proton_transfer_coupled electron transfer (PT_ET) reactions between the menaquinone Q A (MQ 1) and ubiquinone Q B (UQ 1) in the bacterial photosynthetic reaction center of Rhodopseudomona vi...; 关键词：Rhodopseudomena viridis electron transfer proton transfer Q A and Q B DFT

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