the National Natural Science Foundation of China(Nos.21890723 and 21921002);the Science and Technology Department of Sichuan Province(Nos.2021YJ0561)for financial support.
An efficient synthesis of chiral benzannulated spiroketals via catalytic asymmetric[3+2]cycloaddition of exocyclic enol ethers with p-quinones was achieved.The transformation was enabled by a chiral N,N′-dioxides/Tm^...
Project supported by the National Natural Science Foundation of China (Nos. 20025207, 20272071, 20372075, 20321202), the Chinese Academy ot Sciences (“Knowledge Innovation”project, KGCX2-SW-209), and the Major State Basic Research Development Program (No. G2000077502) of China.
Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method...