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funded by the National Key Research and Development Project of China(2022YFC3703203);the National Natural Science Foundation of China(NSFC 42207484,22036004);China Postdoctoral Science Foundation(2021M701777);Ministry of Education,China(T2017002).
Aromatic amine antioxidants(AAs),extensively used in rubber products,and their ozone-photolyzed product pphenylenediamine quinones(PPD-Qs)were found to be pervasive in various environments and with potential ecologica...
supported by the National Natural Science Foundation of China(grant No.U22A20523,32202856,32172912 and 32102723);the Postdoctoral Research Foundation of China(Certificate Number:2023 M731291);Interdisciplinary Integration and Innovation Project of JLU(JLUXKJC2021QZ04);the Graduate Innovation Fund of Jilin University(No.2022001).
The emergence and worldwide dissemination of mobile tigecycline resistance genes tet(X3)/tet(X4)posed an enor-mous threat to the public health.Urgently,feasible strategies must be implemented to restore the clinical e...
supported by the National Natural Science Foundation of China(NSFC 21672170);the Natural Science Basic Research Plan in Shaanxi Province of China(2021JZ-40);Shaanxi Fundamental Science Research Project for Chemistry&Biology(22JHQ007)。
A chiral phosphoric acid catalyzed enantioselective[2+2] cycloaddition of alkynylindols or alkynylnaphthols with quinones is disclosed.A class of functionalized cyclobutenes with excellent yields,diastereo-and enantio...
National Natural Science Foundation of China(No.81960755);Bio-pharmaceutical Major Project of Yunnan Province(No.202002AA100007);Yunnan Fundamental Research Project(No.202001AU070022);Program for Innovative Research Team of Yunnan Province(No.202305AS350001)。
Objective: To explore the proliferation inhibitory effect of quinones from Blaps rynchopetera defense secretion on colorectal tumor cell lines. Methods: Human colorectal cancer cell HT-29, human colorectal adenocarcin...
the National Natural Science Foundation of China(Nos.21890723 and 21921002);the Science and Technology Department of Sichuan Province(Nos.2021YJ0561)for financial support.
An efficient synthesis of chiral benzannulated spiroketals via catalytic asymmetric[3+2]cycloaddition of exocyclic enol ethers with p-quinones was achieved.The transformation was enabled by a chiral N,N′-dioxides/Tm^...
the National Natural Science Foundation of China(22279063 and 21835004);the National Key R&D Program of China(2016YFB0901500);Ministry of Education of China(B12015 and IRT13R30);the Haihe Laboratory of Sustainable Chemical Transformations for financial support。
Novel small sulfur heterocyclic quinones(6a,16adihydrobenzo[b]naphtho[2′,3′:5,6][1,4]dithiino[2,3-i]thianthrene-5,7,9,14,16,18-hexaone(4S6Q)and benzo[b]naphtho[2′,3′:5,6][1,4]dithiino[2,3-i]thianthrene-5,9,14,18-t...
supported by grants from the Singapore National Medical Research Council(CS-IRG,HLCA2022,STaR,OF LCG 000207);a clinical translational research programme in Parkinson’s disease and a Duke-Duke-NUS collaboration pilot grant.
A pathological feature of Parkinson’s disease(PD)is the progressive loss of dopaminergic neurons and decreased dopamine(DA)content in the substantia nigra pars compacta in PD brains.DA is the neurotransmitter of dopa...
XS-N kindly acknowledges a National Research Foundation(NRF)Competitive Support for Unrated Researchers(CSUR)grant,Reference Number:SRUG2203291031.
Plants of the genus Cordia(Boraginaceae family)are widely distributed in the tropical regions of America,Africa,and Asia.They are extensively used in folk medicine due to their rich medicinal properties.This review pr...
Financial support from the National Natural Science Foundation of China(Nos.21702087 and 21801105);the Liaoning Revitalization Talents Program(XLYC1907010 and XLYC1902085);the Research Project Fund of Liaoning Provincial Department of Education(L2020033 and UKZ0375);the Talent Scientific Research Fund of Liaoning Petrochemical University(2016XJJ-078 and 2016XJJ-079)is gratefully acknowledged.
A visible-light-promoteded[3+2]cycloaddition reaction of 2H-azirines with quinones has been developed under mild reaction con-ditions.The reaction provides a general and efficient strategy for the synthesis of the ben...
supported by the National Key Research and Development Program of China(No.2018YFC 0310900);the National Natural Science Foundation of China(Nos.U1605221,82022068,81773866,41906075,and 41576130)。
Four new sesquiterpene quinone meroterpenoids,dysideanones F—G(1—2)and dysiherbols D—E(3—4),were isolated from the marine sponge Dysidea avara collected from the South China Sea.The new structures were elucidated ...