ANTITUMOR

作品数：470被引量：1206H指数：15
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相关机构：北京大学天津医科大学中国药科大学福建省亚热带植物研究所更多>>
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Rational design of platinum(Ⅱ)complexes with orthogonally oriented triazolyl ligand with emission enhancement characteristics for cancer chemotherapy in vivo
《Science China Chemistry》2023年第10期2878-2884,共7页Yeye Ai Zherui Zhang Yuexuan Fei Ruirong Ye Angela Sin-Yee Law Zong-Wan Mao Junqiu Liu Yongguang Li Vivian Wing-Wah Yam 
supported by Zhejiang Provincial Natural Science Foundation of China(LR22B010001,LQ23B010001);the National Natural Science Foundation of China(22201057,21871297);the General Research Fund(GRF)grant from the Research Grants Council of the Hong Kong Special Administrative Region,People’s Republic of China(HKU17303421);the Collaborative Research Fund(CRF)(C7075-21G);Hangzhou Normal University(2021QDL001,2021QDL065);the West Lake Scholar Plan,the Hangzhou Leading Innovation and Entrepreneurship Team Project(TD2022001);the CAS-Croucher Funding Scheme for Joint Laboratory on Molecular Functional Materials for Electronics,Switching and Sensing;support from Sun Yat-Sen University;The University of Hong Kong;the Innovation Technology Commission to the State Key Laboratory of Synthetic Chemistry。
The mitochondria are essential for tumorigenesis and have been regarded as important targets in cancer chemotherapy.Herein,the mitochondria-targeted platinum(Ⅱ)complexes have been prepared.The introduction of the tri...
关键词：platinum(Ⅱ)complexes post-click reaction emission enhancement mitochondria-targeting ANTITUMOR 
Current Status for Oral Platinum (IV) Anticancer Drug Development
《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》2018年第2期231-247,共17页Qian Mi Shunshun Shu Caixia Yang Chuan Gao Xian Zhang Xiao Luo Chonghuan Bao Xia Zhang Jun Niu 
Platinum-based chemotherapeutic drugs such as cisplatin, carboplatin and oxaliplatin are widely applied for the treatment of various types of tumors. However, poor solubility, serious side effects, and more importantl...
关键词：PLATINUM (IV) COMPLEXES Properties Mechanism ANTITUMOR Activity Cancer THERAPY Photoactivatable 
Preparation and characterization of inclusion complexes of antitumor camptothecin with cucurbit[n=7,8]urils被引量：6
《Science China Chemistry》2010年第11期2304-2310,共7页DONG Nan DONG MeiYu ZHAO AnTing ZHU QianJiang TAO Zhu ZHAO Yu 
supported by the Talented Person Project of Guizhou University (2007016);Science and Technology Fund of Guizhou Province (20082294);Governor Foundations of Guizhou Province (200812)
The slightly water-soluble anticancer drug camptothecin(CPT) and its inclusion complexes with cucurbit[n = 7,8]uril(Q[n](n = 7,8)) were investigated.The formation of 1:2 complexes with Q[n](n = 7,8) in aqueous solutio...
关键词：COMPLEXES CAMPTOTHECIN cucurbit[n]uril(n=7 8) dissolution properties stability 
Preliminary Fluorimetric Screening of Fourteen Palladium Complexes as Potential Antitumor Agents
《Science China Chemistry》1993年第10期1216-1223,共8页林辉祥 李志良 戴桂林 毕琼斯 俞汝勤 
Project supported by the National Education Commission Foundation and the National Natural Science Foundation of China.
Making use of the fact that the combination of a drug substance with DNA may inhibit the duplication, synthesis and proliferation of DNA and the consistency of the in vivo and in vitro interactions, the authors worked...
关键词：fluorimetric SCREENING palladium(Ⅱ) COMPLEXES PRELIMINARY SCREENING of ANTITUMOR DRUGS fluorescence probe. 
THE CRYSTAL AND MOLECULAR STRUCTURE OF DIHYDROXY (MALONATO)-DIAMMINE PLATINUM (Ⅱ)
《Chinese Science Bulletin》1983年第2期200-205,共6页李根培 唐有祺 管荫桐 唐雯霞 戴安邦 
Ⅰ. INTRODUCTION A few platinum complexes having antitumor properties have attracted much interest in recent years, Now we have synthesized and tested the Pt(Ⅳ) malonato complex, which appears to exhibit significant ...
关键词：PLATINUM agonal subsequent REPORTING ANTITUMOR COMPLEXES MALONATO FITTING filtered longer 
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