supported by the Program of the National Natural Science Foundation of China(Nos.22178170,22378195 and 22208156);the Six Talent Peaks Project in Jiangsu Province(No.SWYY-045);the Jiangsu Province Natural Science Foundation for Youth(No.BK20200685).
The peroxygenases are ideal biocatalysts for the selective oxyfunctionalisation of stable C-H bonds.However,the catalytic efficiency of this approach is limited due to enzyme lability toward oxidant H_(2)O_(2).Althoug...
supported by the National Natural Science Foundation of China (No.32001633);the Key Program of Natural Science Foundation of China (No.31930084);Guangzhou Science and technology planning project (No.202102020370)。
Unspecific peroxygenases(UPOs, EC 1.11.2.1) is a kind of thioheme enzyme capable of catalyzing various oxidations of inert C–H bonds using H_(2)O_(2) as an oxygen donor without cofactors. However, the enhancement of ...
funded by the National Key Research and Development Program of China(2021YFC2102700);was Supported by the Key Science and Technology Innovation Project of Hubei Province(2021BAD001);as well as the Research Program of State Key Laboratory of Biocatalysis and Enzyme Engineering。
Unspecific peroxygenases(UPOs)are glycosylated enzymes that provide an efficient method for oxyfunctionalizing a variety of substrates using only hydrogen peroxide(H2O2)as the oxygen donor.However,their poor heterolog...
the National Key Research and Development Program of China(2019YFA0905100);the National Natural Science Foundation of China(32025001,32071266 and 32170088);the Shandong Provincial Natural Science Foundation(ZR2019ZD20);the State Key Laboratory of Microbial Technology Open Projects Fund(Project NO.M2022-01).
Indigoids,a class of bis-indoles,have long been applied in dyeing,food,and pharmaceutical industries.Recently,interest in these‘old’molecules has been renewed in the field of organic semiconductors as functional bui...
It is demonstrated that (3Z)-nonenal (NON) and (3Z)-hexenal (HEX) are oxidized in a cascade by lipoxygenase (LOX) and hydroperoxide peroxygenase (HP peroxygenase) into (2E)-4-hydroxy-2- nonenal (HNE) and (2E)-4-hydrox...
The cardiovascular effects of vitamin C (VitC) could be mediated by epoxyeicosatrienoic acids (EETs). We aimed to study the mechanism of VitC-dependent microsomal formation of cis- and trans-EETs and the regulation of...