LONG-CIRCULATING

作品数:5被引量:6H指数:2
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相关领域:医药卫生更多>>
相关期刊:《Acta Pharmacologica Sinica》《Science China Chemistry》《National Science Review》《Acta Pharmaceutica Sinica B》更多>>
相关基金:国家自然科学基金更多>>
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Bright,photostable and long-circulating NIR-II nanoparticles for whole-process monitoring and evaluation of renal transplantation
《National Science Review》2024年第2期202-215,共14页Rongyuan Zhang Ping Shen Yu Xiong Tianjing Wu Gang Wang Yucheng Wang Liping Zhang Han Yang Wei He Jian Du Xuedong Wei Siwei Zhang Zijie Qiu Weijie Zhang Zheng Zhao Ben Zhong Tang 
supported by the National Natural Science Foundation of China(52003228,52273197,21788102);the National Key Research and Development Program of China(2023YFB3810001);the Shenzhen Key Laboratory of Functional Aggregate Materials(ZDSYS20211021111400001,JCYJ20220818103007014,JCYJ2021324134613038,KQTD20210811090142053,JSGG20220606141800001,GJHZ20210705141810031);the Innovation and Technology Commission(ITC-CNERC14SC01).
Kidney transplantation is the gold standard for the treatment of end-stage renal diseases(ESRDs).However,the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transpl...
关键词:aggregation-induced emission NIR-II imaging kidney transplantation nano-contrast agent ANGIOGRAPHY 
The long-circulating effect of pegylated nanoparticles revisited via simultaneous monitoring of both the drug payloads and nanocarriers被引量:1
《Acta Pharmaceutica Sinica B》2022年第5期2479-2493,共15页Wufa Fan Haixia Peng Zhou Yu Luting Wang Haisheng He Yuhua Ma Jianping Qi Yi Lu Wei Wu 
supported by the National Natural Science Foundation of China(Nos.81872815,82030107,and 81690263);Science and Technology Commission of Shanghai Municipality(No.19XD1400300,China)。
The long-circulating effect is revisited by simultaneous monitoring of the drug payloads and nanocarriers following intravenous administration of doxorubicin(DOX)-loaded methoxy polyethylene glycol-polycaprolactone(mP...
关键词:LONG-CIRCULATING In vivo fate Aggregation-caused quenching NANOPARTICLES mPEG-PCL DOXORUBICIN Drug delivery Pharmacokinetics 
Light-activated nitric-oxide overproduction theranostic nanoplatform based on long-circulating biomimetic nanoerythrocyte for enhanced cancer gas therapy
《Science China Chemistry》2021年第10期1796-1810,共15页Cheng-Guang Wu Jing-Lan Liang Xiang Wang Xiaoyan Zhou Xiang Cai Jun Xu Meng Wang Wen-Bo Wang Dong Ma Wei Xue 
the National Natural Science Foundation of China(31870943);the Thousands of Doctors(Postdoctoral)Program of Guangdong Academy of Sciences(2019GDASYL-0103015);the Basic and Applied Basic Research Fund of Guangdong Province(2019A1515110663);the Traditional Chinese Medicine Bureau of Guangdong Province(20201109)。
The limited intratumoral perfusion of nitric oxide(NO)-carrying nanoparticles into solid tumors caused by the inherent biological barriers in vivo greatly attenuates their generated efficacy. Herein, through entrappin...
关键词:nitric oxide biomimetic nanoerythrocyte PTT/NO synergistic therapy bimodal imaging 
Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery被引量:2
《Acta Pharmaceutica Sinica B》2021年第2期560-571,共12页Shaojun Peng Boshu Ouyang Yongjie Xin Wei Zhao Shun Shen Meixiao Zhan Ligong Lu 
financially supported by the National Key Research and Development Program of China(No.2017YFA0205200);the National Natural Science Foundation of China(Grant No.81903165 and 81901857);the Chinese Postdoctoral Foundation(Grant No.2019M663361,China)
Tumor microenvironment has been widely utilized for advanced drug delivery in recent years,among which hypoxia-responsive drug delivery systems have become the research hotspot.Although hypoxia-responsive micelles or ...
关键词:Hypoxia-degradable Zwitterionic nanogel Long blood circulation Drug release Drug delivery 
Body distribution and in situ evading of phagocytic uptake by macrophages of long-circulating poly (ethylene glycol) cyanoacrylate-co-nhexadecyl cyanoacrylate nanoparticles被引量:3
《Acta Pharmacologica Sinica》2005年第12期1512-1518,共7页Min HUANG Wei WU Jun QIAN Dan-jing WAN Xiu-li WEI Jian-hua ZHU 
Project supported by the Shanghai Municipal Committee of Science and Technology(Grant No 0243nm067);the Shanghai Education Bureau for Excellent Young High Education Teacher Candidates(Grant No 03YQHB008).
Aim: To investigate the body distribution in mice of [^14C]-labeled poly methoxyethyleneglycol cyanoacrylate-co-n-hexadecyl cyanoacrylate (PEG-PHDCA) nanoparticles and in situ evading of phagocytic uptake by mouse ...
关键词:nanotechnology tissue distribution polyethylene glycols cynoacrylates polymers SPLEEN 
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