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Rectal abscess secondary to foreign body insertion:A case report
《World Journal of Clinical Cases》2025年第18期78-84,共7页Cristina Isabel Martínez-Hincapie Daniel González-Arroyave Carlos M Ardila 
BACKGROUND Rectal foreign bodies,though uncommon,present diagnostic and therapeutic challenges,particularly when they result from accidental ingestion.The non-specific symptoms and the potential for serious complicati...
关键词:Rectal foreign bodies ABSCESS ENDOSONOGRAPHY Colonoscopic polypectomy Chronic inflammation Case report 
Innovative genome editing in plants: a transposase and CRISPR combination approach
《Science China(Life Sciences)》2025年第3期893-894,共2页Hamza Sohail Iqra Noor Xuehao Chen Xiaodong Yang 
supported by Jiangsu specially-appointed professor fund(337060046);the Yangzhou University Startup Fund(137012599).
Transgenic plants are extensively utilized in research,enabling scientists to explore gene functions in controlled environments,leading to crops with higher productivity and greater resistance to biotic and abiotic st...
关键词:integration INSERTION CROPS 
Learning-based robot assembly method for peg insertion tasks on inclined hole using time-series force information
《Biomimetic Intelligence & Robotics》2025年第1期116-123,共8页Zhifei Shen Zhiyong Jiang Jingwang Zhang Jun Wu Qiuguo Zhu 
supported by the National Key R&D Program of China(2022YFB4701502);the“Leading Goose”R&D Program of Zhejiang(2023C01177);the 2035 Key Technological Innovation Program of Ningbo City(2024Z300).
This paper presents a novel method for learning force-aware robot assembly skills,specifically targeting the peg insertion task on inclined hole.For the peg insertion task involving inclined holes,we employ one-dimens...
关键词:Manipulator assembly Peg insertion Force information Contact state Dual-arm 
Review on Multi-objective Dynamic Scheduling Methods for Flexible Job Shops and Application in Aviation Manufacturing
《Transactions of Nanjing University of Aeronautics and Astronautics》2025年第1期1-24,共24页MA Yajie JIANG Bin GUAN Li CHEN Lijun HUANG Binda CHEN Zhi 
supported by the National Key Research and Development Program Project(No.2021YFB3301300).
Intelligent production is an important development direction in intelligent manufacturing,with intelligent factories playing a crucial role in promoting intelligent production.Flexible job shops,as the main form of in...
关键词:flexible job shop dynamic scheduling machine breakdown job insertion multi-objective optimization 
High-throughput experimentation and machine learning-promoted synthesis of α-phosphoryloxy ketones via Ru-catalyzed P(O)O–H insertion reactions of sulfoxonium ylides
《Science China Chemistry》2025年第2期679-686,共8页An Lin Jingyuan Liu Yougen Xu Haiting Wu Yating Chen Yan Zhang Lebin Su Xiaodan Zhao Kuangbiao Liao 
supported by the National Natural Science Foundation of China(22372044,22393892,22002169,22071249);the Guangdong Basic and Applied Basic Research Foundation(2024A1515012583,2019A1515111111);the Major Program of Guangzhou National Laboratory(GZNL2023A02012)。
Herein,we report a novel and highly efficient method for the synthesis ofα-phosphoryloxy carbonyl compounds via Rucatalyzed P(O)O–H insertion reactions of sulfoxonium ylides and phosphinic acids,with the assistance ...
关键词:α-phosphoryloxy ketones high-throughput experimentation machine learning P(O)O-H insertion sulfoxonium ylides 
Deep-Learning-Coupled Numerical Optimization Method for Designing Geometric Structure and Insertion-Withdrawal Force of Press-Fit Connector
《Acta Mechanica Solida Sinica》2025年第1期78-90,共13页Mingzhi Wang Bingyu Hou Weidong Wang 
supported by the National Natural Science Foundation of China(No.52005378);the opening project fund of Materials Service Safety Assessment Facilities(No.MSAF-2021-107).
The press-fit connector is a typical plug-and-play solderless connection,and it is widely used in signal transmission in fields such as communication and automotive devices.This paper focuses on inverse designing and ...
关键词:Press-fit connector Compliant pin Insertion-withdrawal force Optimization design Neural network model 
Foxp3 inhibitory peptide encapsulated in a novel CD25-targeted nanoliposome promotes efficient tumor regression in mice
《Acta Pharmacologica Sinica》2025年第1期171-183,共13页Aejandro Serrano Noelia Casares lnaki F.Troconiz Teresa Lozano Juan J.Lasarte Sara Zalba Maria J.Garrido 
This research was funded by Ministry of Science;Innovation(PID2019-108989RB-100;PID2021-1282830A-00,PLEC2021-008094 MCIN/AEI/10.13039/501100011033);Gobierno de Navarra Industria(0011-1411-2022-000088;SOCRATHES project);Paula and Rodger Riney Foundation and Fundacion Bita;This work was supported by an ADA(University of Navarra)scholarship of Alejandro Serrano.
P60,a Foxp3 inhibitory peptide,can hinder the regulatory T cell(Treg)activity and impair tumor proliferation.However,low systemic stability and poor specificity have led to daily dosing to achieve therapeutic effect.T...
关键词:Treg cells CD25 lipid nanoparticle PEG chain lengths post-insertion translation approach 
Photoinduced radical sulfur dioxide insertion with asymmetric cyclization of alkenes:accessingβ-chiral sulfones bearing S-stereocentric cyclic sulfinamides
《Science China Chemistry》2025年第1期257-263,共7页Jiapian Huang Chenxin Wang Xu Wang Xiaoyu Zhou Wei Xiao Jie Wu 
supported by the National Natural Science Foundation of China(22171206);the Natural Science Foundation of Zhejiang Province(LZ23B020001);the Zhejiang Provincial Ten Thousand Talent Program(2023R5244);the Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(2020ZD04)。
The generation of variousβ-chiral sulfones bearing chiral cyclic sulfinamides through photoredox-catalyzed sulfur dioxide insertion with asymmetric radical cyclization is described.This method features a broad substr...
关键词:β-chiral sulfones chiral cyclic sulfinamides sulfur dioxide insertion asymmetric radical cyclization STEREOSELECTIVITY 
Synthesis,crystal structure,and DNA‑binding of binuclear lanthanide complexes based on a multidentate Schiff base ligand
《无机化学学报》2024年第12期2486-2496,共11页GUAN Xiaofen LIU Yating LI Jia HU Yiwen DING Haiyuan SHI Yuanjing WANG Zhiqiang WANG Wenmin 
山西省应用基础研究基金(No.202303021212256)资助。
Two new dinuclear lanthanidecomplexes,namely[Ln_(2)(dbm)_(2)(HL)_(2)(CH_(3)OH)_(2)]·4CH_(3)OH[Ln=Tb(1)and Dy(2),Hdbm=dibenzoylmethane]have been synthesized using prepared multidentate Schiff base ligand H_(3)L(hydrox...
关键词:binuclear lanthanide complexes crystal structures multidentate Schiff base DNA INSERTION 
A PCR-independent,annealing-free cloning method for the insertion of short DNA fragments
《Acta Biochimica et Biophysica Sinica》2024年第12期1886-1890,共5页Linbo Li Jin Yan Yuan Qi Zhenglong Xiang Na Jiang Tongkang Yuan Zhenyi Wang Yuan Wang Huaizhe Zhan Shiyi Liu Li Zhao Jing Xu Xiaowei Lei Yuxuan Liu Gui Wang Jiayang Xie Zhenming Guo Chunhai Cai Shan Bian 
supported by the grants from the National Natural Science Foundation of China(Nos.32271019 to S.B.,and 32300810 to Z.G.);the National Key R&D Program of China(Nos.2020YFA0112500 and 2021YFA1100400 to S.B.);the China National Postdoctoral Program for Innovative Talents(No.BX20220230 to Z.G.);the Shanghai Sailing Program(No.22YF1436100 to Z.G.);the Natural Science Foundation of Shanghai Municipality(No.22ZR1462600 to S.B.);the Fundamental Research Funds for the Central Universities(Nos.22120230454 and 22120230292 to S.B.).
Since two major biotechnological advances,the discovery of restriction endonucleases in the 1970s[1]and the invention of the polymerase chain reaction(PCR)technique in the 1980s[2],molecular cloning has become a funda...
关键词:INSERTION ANNEALING CLONING 
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