Idiopathic asthenozoospermia,a common factor in male infertility,is characterized by altered sperm motility function in fresh ejaculate.Although theβ-defensin 126(DEFB126)protein is associated with asthenozoospermia,...
supported by the National Natural Science Fund of China(No.81660263 and No.81300541);the China Postdo.ctoral Science Foundation(No.2015M582760XB);the Doctoral Fund of Affiliated Hospital of Guiyang Medical College(No.C-2012-6).
To explore the relationship between genetic polymorphisms of metabolic enzymes such as CYP1A1,CYP2D6,GSTM1,GSTT1,and GSTP1 and idiopathic male infertility.By observing the efficacy of antioxidants in the treatment of ...
Dear Editor, Lifelong premature ejaculation (LPE) is a type of sexual dysfunction in males and has three characteristics: (1) an intravaginal ejaculatory latency time (IELT) of 〈 1 rain; (2) insufficient co...
Previous genome-wide association studies have identified variants in the diacylglycerol kinase kappa (DGKtO gene associated with hypospadias in populations of European descent. However, no variants of DGKKwere confir...
The purpose of our meta-analysis is to examine the associations between three single nucieotide polymorphisms of endothelial nitric oxide synthase (eNOS) gene, G894T, intron 4 and T-786C, and the risk of erectile dy...
ACKNOWLEDGMENTS XHZ is supported by the National Natural Science Foundation of China (No. 81270843 and No. 81160086).Supplementary information is linked to the online version of the paper on the Asian Journal of Andrology website.
To investigate the association of single nucleotide polymorphism 260 and 386 (SNP260 and SNP386) gene with male infertility, an electronic search was performed to identify case-control studies evaluating the relatio...
The reported effects of the glutathione S-transferase (GSTs) genes (GSTM1, GSTTI, and GSTP1) on male factor infertility have been inconsistent and even contradictory. Here, we conducted a case-control study to inv...
In this study, we evaluated genetic variants of the androgen metabolism genes CYP17A1, CYP3A4, and CYP3A43 to determine whether they play a role in the development of prostate cancer (PCa) in Korean men. The study p...
In spite of its long history and high prevalence, the exact pathophysiology of premature ejaculation (PE) remains to be unknown? Over a decade ago, Waldinger et al.2 initially suggested that hypersensitivity of 5-H...
We appreciate and thank Drs Saitz and Serefoglu for their positive and sympathetic words on our article.1 Indeed, our genetic studies have shown that 5-HTTLPR polymorphism, 5-HT1A receptor gene polymorphism and 5-HT2c...