POLYMORPHISMS

作品数:634被引量:2320H指数:17
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相关作者:王荣顾民韩志坚陶俊王子杰更多>>
相关机构:南京医科大学首都医科大学北京协和医院广西医科大学第一附属医院更多>>
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DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China
《Asian Journal of Andrology》2022年第6期607-614,共8页Jiao-Yu He Jian-Ying Peng Qiu-Fu Li Xiao-Li Lin Yan-Ru Cui Shi-Yu Ma Shi-Yun Fan Yi-Ran Liu Zhi-Lin Song Jun-Hang Deng Xia Wei Xian-Ping Ding 
Idiopathic asthenozoospermia,a common factor in male infertility,is characterized by altered sperm motility function in fresh ejaculate.Although theβ-defensin 126(DEFB126)protein is associated with asthenozoospermia,...
关键词:β-defensin 126 idiopathic asthenozoospermia in silico analysis single-nucleotide polymorphisms 
Metabolic enzyme gene polymorphisms predict the effects of antioxidant treatment on idiopathic male infertility被引量:1
《Asian Journal of Andrology》2022年第4期430-435,共6页Hong-Yan Zhang Yi Mu Pan Chen Dong-Dong Liu Ke-Hang Chen Qi Yu Jun He Fa Sun Jun-Ping Xing Kai-Fa Tang 
supported by the National Natural Science Fund of China(No.81660263 and No.81300541);the China Postdo.ctoral Science Foundation(No.2015M582760XB);the Doctoral Fund of Affiliated Hospital of Guiyang Medical College(No.C-2012-6).
To explore the relationship between genetic polymorphisms of metabolic enzymes such as CYP1A1,CYP2D6,GSTM1,GSTT1,and GSTP1 and idiopathic male infertility.By observing the efficacy of antioxidants in the treatment of ...
关键词:GENE INFERTILITY metabolic enzyme oxidative stress POLYMORPHISMS 
Association between polymorphisms in the human serotonin transporter gene and lifelong premature ejaculation in the Han population
《Asian Journal of Andrology》2018年第1期103-104,共2页Dang-Wei Peng Jing-Jing Gao Yuan-Yuan Huang Dong-Dong Tang Pan Gao Chao Li Wei-Qun Liu Xian-Ming Dou Jun Mao Yao Zhang Hao Geng Xian-Sheng Zhang 
Dear Editor, Lifelong premature ejaculation (LPE) is a type of sexual dysfunction in males and has three characteristics: (1) an intravaginal ejaculatory latency time (IELT) of 〈 1 rain; (2) insufficient co...
Association between diacylglycerol kinase kappa variants and hypospadias susceptibility in a Han Chinese population被引量:3
《Asian Journal of Andrology》2018年第1期85-89,共5页Hua Xie Xiao-Ling Lin Song Zhang Ling Yu Xiao-Xi Li Yi-Chen Huang Yi-Qing Lyu Hai-Tao Chen Jianfeng Xu Fang Chen 
Previous genome-wide association studies have identified variants in the diacylglycerol kinase kappa (DGKtO gene associated with hypospadias in populations of European descent. However, no variants of DGKKwere confir...
关键词:association study diacylglycerol kinase kappa HYPOSPADIAS POLYMORPHISMS 
Association of endothelial nitric oxide synthase polymorphisms with an increased risk of erectile dysfunction被引量:4
《Asian Journal of Andrology》2017年第3期330-337,共8页Lei Gao Zhifeng Zhao Fengfu Guo Yan Liu Jianhua Guo Yang Zhao Zhong Wang 
The purpose of our meta-analysis is to examine the associations between three single nucieotide polymorphisms of endothelial nitric oxide synthase (eNOS) gene, G894T, intron 4 and T-786C, and the risk of erectile dy...
关键词:endothelial nitric oxide synthase erectile dysfunction G894T intron 4 META-ANALYSIS single nucleotide polymorphism 
Association of polymorphisms of A260G and A386G in DAZL gene with male infertility: a meta-analysis and systemic review被引量:3
《Asian Journal of Andrology》2016年第1期96-101,共6页Ping Chen Xiao Wang Chang Xu He Xiao Wen-Hao Zhang Xing-Huan Wang Xin-Hua Zhang 
ACKNOWLEDGMENTS XHZ is supported by the National Natural Science Foundation of China (No. 81270843 and No. 81160086).Supplementary information is linked to the online version of the paper on the Asian Journal of Andrology website.
To investigate the association of single nucleotide polymorphism 260 and 386 (SNP260 and SNP386) gene with male infertility, an electronic search was performed to identify case-control studies evaluating the relatio...
关键词:deleted in azoospermia-like male infertility META-ANALYSIS POLYMORPHISM single nucleotide polymorphisms 
Association of polymorphisms in glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) with idiopathic azoospermia or oligospermia in Sichuan, China被引量:5
《Asian Journal of Andrology》2015年第3期481-486,共6页Da-Ke Xiong 
The reported effects of the glutathione S-transferase (GSTs) genes (GSTM1, GSTTI, and GSTP1) on male factor infertility have been inconsistent and even contradictory. Here, we conducted a case-control study to inv...
关键词:genetic polymorphism glutathione S-transferase idiopathic infertility male factor 
Association between cytochrome CYP17A1, CYP3A4, and CYP3A43 polymorphisms and prostate cancer risk and aggressiveness in a Korean study population被引量:3
《Asian Journal of Andrology》2015年第2期285-291,I0010,共8页Jun Hyun Han Yong Seong Lee Hae Jong Kim Shin Young Lee Soon Chul Myung 
In this study, we evaluated genetic variants of the androgen metabolism genes CYP17A1, CYP3A4, and CYP3A43 to determine whether they play a role in the development of prostate cancer (PCa) in Korean men. The study p...
关键词:ANDROGENS CYP17A1 CYP3A4 CYP3A43 GENETICS prostatic neoplasms 
Gene mapping of serotoninergic system polymorphisms provides insight on pathology and treatment of men with lifelong premature ejaculation
《Asian Journal of Andrology》2014年第4期643-643,共1页Theodore R Saitz Ege Can Serefoglu 
In spite of its long history and high prevalence, the exact pathophysiology of premature ejaculation (PE) remains to be unknown? Over a decade ago, Waldinger et al.2 initially suggested that hypersensitivity of 5-H...
Re: Gene mapping of serotoninergic system polymorphisms provides insight on pathology and treatment of men with lifelong premature ejaculation
《Asian Journal of Andrology》2014年第4期643-643,共1页Paddy KC Janssen Ron van Schaik Berend Olivier Marcel D Waldinger 
We appreciate and thank Drs Saitz and Serefoglu for their positive and sympathetic words on our article.1 Indeed, our genetic studies have shown that 5-HTTLPR polymorphism, 5-HT1A receptor gene polymorphism and 5-HT2c...
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