National Natural Science Foundation of China(Grant No.32100776 to Y.L.C.,and No.32371309 to E.Y.K.);The genetic modification of cell lines and mouse were supported by 111 program(D20036).
The downregulation of Cadm4 (Cell adhesion molecular 4) is a prominent feature in demyelination diseases, yet, the underlying molecular mechanism remains elusive. Here, we reveal that Cadm4 undergoes specific palmitoy...
This study was funded by grants from Taishan Scholarship(No.tspd20181201);the National Science Foundation of China(Key program 81830017 and No.81902051,81902443);the National Natural Science Fund for Outstanding Youth Fund(81425012);Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of Shandong,Key Research and Development Program of Shandong(2019GSF108238);the COVID-19 emergency tackling research project of Shandong University(Grant No.2020XGB03);the Natural Science Foundation of Jiangsu Province(BK20200225)。
Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the causative agent of the unprecedented coronavirus disease 2019(COVID-19).SARS-CoV-2 entry into host cells is mediated by the viral transmemb...
A recent study by Yao et al.published in Nature Biomedical Engineering showed the importance of palmitoylation in regulat-ing PD-L1 protein stability and trafficking.1 These researchers developed a competitive inhibit...