funded by the National Natural Science Foundation of China(21576134 and 21706126);the National Key Research and Development Program(2016YFA0204300)。
Here,a dopa decarboxylase(DDC)from Harmonia axyridis was heterogeneously expressed in Escherichia coli for the efficient biosynthesis of dopamine.For the production of recombinant DDC,the cultivation conditions includ...
Supported by the National Natural Science Foundation of China(20676013,61240047)
The approaches to discrete approximation of Pareto front using multi-objective evolutionary algorithms have the problems of heavy computation burden, long running time and missing Pareto optimal points. In order to ov...
Supported by the National Natural Science Foundation of China (20476007, 20676013)
In this study, Saccharomyces cerevisiae (baker's yeast) was produced in a fed-batch bioreactor at the optimal dissolved oxygen concentration (DOC) and growth medium temperature. However, it is very difficult to contro...
Supported by the National Natural Science Foundation of China (20676013)
An iterative optimization strategy for fed-batch fermentation process is presented by combining a run-to-run optimization with swarm energy conservation particle swarm optimization (SEC-PSO). SEC-PSO, which is designe...
Supported by the National Natural Science Foundation of China(20476007 20676013)
On-line estimation of unmeasurable biological variables is important in fermentation processes,directly influencing the optimal control performance of the fermentation system as well as the quality and yield of the ta...
The production of 2,3-butanediol by Klebsiella pneumoniae from glucose supplemented with different salts was studied. A suitable medium composition was defined by response surface experiments. In a medium containing g...
Supported by the National Natural Science Foundation of China,No.29476248 and Trans-Century Training Program Foundation for the Talents by the State Education Commission.
In this paper,a novel fuzzy neural network model,in which an adjustable fuzzy sub-space was designed by uniform design,has been established and used in fed-batch yeast fermentationas an example.A brand-new optimizatio...