This work was supported by the National Key Research and Development Program of China(2018YFA0900300);National Natural Science Foundation of China(31972854);Natural Science Foundation of Jiangsu Province(BK20200085);Key Research and Development Program of Jiangsu Province(BE2019628);Fundamental Research Funds for the Central Universities(JUSRP22036).
N-Acetyl-d-neuraminic acid(NeuAc),a well-known and well-studied sialic acid,is found in cell surface glycolipids and glycoproteins,where it performs a variety of biological functions.The use of NeuAc as a nutraceutica...
We thank the National Key Scientifc Instrument and Equipment Development Project of China(2013YQ17052504);the Program for Changjiang Scholars and Innovative Research Team in the University of Ministry of Education of China(IRT_15R55);the seventh group of Hundred-Talent Program of Shanxi Province(2015);The Key Project of Research and Development Plan of Shaanxi(2017ZDCXLSF-01-02-01)for fnancial support.
L-DOPA is a major drug for the treatment of Parkinson’s disease,and microbial enzymatic synthesis is an essential way for its industrial production.The expression of tyrosine phenol-lyase(TPL)derived from Erwinia her...