云南高校图书馆联盟文献共享服务平台- L-DOPA

L-DOPA: 作品数：86被引量：264H指数：8; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：曹奕鸯李爱萍郑开斌王丹巧彭珍荣更多>>; 相关机构：河南工业大学江南大学福建农林大学河南工程学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金国家高技术研究发展计划更多>>

舒肌汤对L-DOPA诱发的帕金森病肌僵直大鼠的作用及其脑组织TH、DA含量和FosB、p-ERK蛋白的影响: 《中国中医药科技》2024年第5期785-790,共6页刘超平孙婷鲍玺; 浙江省中医药科技计划项目(2022ZA110);浙江省湖州市公益性应用研究项目(2020GY38)。; 目的:观察舒肌汤对左旋多巴(Levodopa,L-DOPA)诱发的帕金森病(Parkinson’s disease,PD)肌僵直模型大鼠的影响,并探讨其作用机制。方法:L-DOPA诱导建立PD肌僵直大鼠模型,随机分为模型组(等体积生理盐水),舒肌汤低、中、高剂量组(10、20...; 关键词：帕金森病肌僵直左旋多巴舒肌汤多巴胺酪氨酸氢化酶 FOSB P-ERK 大鼠

Colorimetric Recognition of 3,4-Dihydroxy-D,L-phenylalanine with Tetrapeptide-modified Copper Nanoparticles as Chiral Nanozymes: 《Chemical Research in Chinese Universities》2023年第6期1092-1099,共8页TIAN Lin CHENG Cheng ZHAO Zhenwen LIU Wei QI Li; supported by the National Natural Science Foundation of China(No.22274159)。; The construct of artificial nanocatalyts by simulating natural enzymes and thereby bringing new properties for practical applications is still a challenging task to date.In this study,chiral tetrapeptide(L-phenylalani...; 关键词：Chiral nanozyme Copper nanoparticle 3 4-Dihydroxy-D L-phenylalanine(D L-DOPA) ENANTIOSELECTIVITY Tetrapeptide ligand

口服可乐定联合左旋多巴(L-dopa)在矮小儿童生长激素激发试验中的观察与护理对策: 《护理学》2022年第2期222-227,共6页黄林燕李素萍; 目的:通过总结53例口服可乐定联合左旋多巴(L-dopa)进行生长激素激发试验的护理经验,探讨安全、顺利完成可乐定联合左旋多巴(L-dopa)对矮小患儿进行生长激素激发试验观察与护理对策。方法:回顾性分析我院自2020年1月~2021年10月收治住院...; 关键词：可乐定左旋多巴(L-dopa) 激发试验矮小儿童观察护理对策

Constitutive expression of tyrosine phenol‑lyase from Erwinia herbicola in Escherichia coli for L‑DOPA production: 《Systems Microbiology and Biomanufacturing》2022年第1期186-192,共7页Mengqing Tang Yajun Bai Tai‑Ping Fan Xiaohui Zheng Yujie Cai; We thank the National Key Scientifc Instrument and Equipment Development Project of China(2013YQ17052504);the Program for Changjiang Scholars and Innovative Research Team in the University of Ministry of Education of China(IRT_15R55);the seventh group of Hundred-Talent Program of Shanxi Province(2015);The Key Project of Research and Development Plan of Shaanxi(2017ZDCXLSF-01-02-01)for fnancial support.; L-DOPA is a major drug for the treatment of Parkinson’s disease,and microbial enzymatic synthesis is an essential way for its industrial production.The expression of tyrosine phenol-lyase(TPL)derived from Erwinia her...; 关键词：L-DOPA Tyrosine phenol-lyase Constitutive promoters Fed-batch mode

β-细辛醚联合左旋多巴对帕金森病大鼠单胺类神经递质的影响被引量：8: 《中成药》2021年第10期2800-2804,共5页黄丽平周中流宁百乐张芹欣邓敏贞; 国家自然科学基金项目(31900297,81904104);中国博士后科学基金面上项目(2021M690759);广东省重点学科科研项目(2019-GDXK-0025);广东省中医药局科研基金项目(20211203);燕岭优秀青年教师培育计划项目(YL20200210);岭南师范学院科学研究项目(QL1410,ZL1801)。; 目的研究β-细辛醚联合左旋多巴(L-dopa)对帕金森病大鼠单胺类神经递质的影响。方法 70只大鼠通过脑立体定位仪于内侧前脑束(MFB)注射6-羟基多巴制备帕金森病模型,随机分为模型组、美多巴组(75 mg/kg),L-dopa组(60 mg/kg)、β-细辛醚组(...; 关键词：Β-细辛醚左旋多巴(L-dopa) 帕金森病单胺类神经递质

Maximizing ionic transport of Li1+xAlxTi2-xP3O12 electrolytes for all-solid-state lithium-ion storage:A theoretical study: 《Journal of Materials Science & Technology》2021年第14期45-51,共7页Tiantian Wang Jun Mei Jianjun Liu Ting Liao; supported by the honored scholarship of Queensland University of Technology,Australian Research Council(ARC)through ARC Future Fellowship projects(FT 160100281 and FT180100387);ARC Discovery Project(DP160102627)。; The concept of all-solid-state batteries provides an efficient solution towards highly safe and long-life energy storage,while the electrolyte-related challenges impede their practical application.Li1+xAlxTi2-xP3O12(0...; 关键词：Density Functional Theory Solid-state-electrolyte Li ionic conductivity Bond angle variance Al-dopant

Dyskinesia is Closely Associated with Synchronization of Theta Oscillatory Activity Between the Substantia Nigra Pars Reticulata and Motor Cortex in the Off L-dopa State in Rats被引量：2: 《Neuroscience Bulletin》2021年第3期323-338,共16页Jiazhi Chen Qiang Wang Nanxiang Li Shujie Huang Min Li Junbin Cai Yuzheng Wang Huantao Wen Siyuan Lv Ning Wang Jinyan Wang Fei Luo Wangming Zhang; supported by the National Natural Science Foundation of China(81771210);the Natural Science Foundation of Guangdong Province,China(2015A030313288)。; Excessive theta(θ)frequency oscillation and synchronization in the basal ganglia(BG)has been reported in elderly parkinsonian patients and animal models of levodopa(L-dopa)-induced dyskinesia(LID),particularly theθo...; 关键词：Parkinson's disease DYSKINESIA Substantia nigra pars reticulata Primary motor cortex SYNCHRONIZATION

Peroxidase-Like Reactivity at Iron-Chelation Sites in a Mesoporous Synthetic Melanin: 《CCS Chemistry》2021年第3期1483-1490,共8页Yijun Xie Kelsey A.Krug Kristine S.Cay Mark Kalaj Naneki C.McCallum Zofia E.Siwicka Zhao Wang Nathan C.Gianneschi Michael D.Burkart Jeffrey D.Rinehart; support from the Air Force of Scientific Research MURI(grant no.FA9550-18-1-0142);supported by the National Science Foundation(grant no.ECCS-1542148);M.K.is supported by the Department of Defense(DoD)through the National Defense Science and Engineering Graduate(NDSEG)Fellowship Program.; High catalytic activity and substrate specificity make enzymes a rich source of inspiration for catalyst development.Co-opting the advantages of natural materials while tuning them to a modified form and purpose,howev...; 关键词：L-DOPA MESOPOROSITY peroxidase-like reactivity iron ion chelation catalysis

Metal ion-promoted fabrication of melanin-like poly(L-DOPA)nanoparticles for photothermal actuation被引量：4: 《Science China Chemistry》2020年第9期1295-1305,共11页Xianheng Wang Lei Yang Peng Yang Wancai Guo Quan-Ping Zhang Xianhu Liu Yiwen Li; the National Natural Science Foundation of China(21774079;21975167);the National Key R&D Program of China(2019YFA0904500);the State Key Laboratory Cultivation Base for Nonmetal Composites and Functional Materials;Southwest University of Science and Technology(17kffk07);the Fundamental Research Funds for Central Universities。; Melanin-inspired polymers are currently the focus of growing interest for a wide range of applications ranging from energy to biomedical area.Whilst researchers have made numerous attempts to prepare and utilize polyd...; 关键词：MELANIN poly(L-DOPA)nanoparticle metal ion PHOTOTHERMAL actuator

带不同侧链的含L-DOPA环二肽的合成及其DPPH自由基清除活性的测试被引量：1: 《海南大学学报（自然科学版）》2019年第4期322-329,共8页何延淼张小燕赵露露胡碧煌刘中强; 国家自然科学基金(21462014); 本文采用了一种温和的合成策略成功地制备了L-DOPA与侧链含羟基的Thr或含羧基的Asp形成的环二肽.另外,以Val为例,本文又探索了一种新的合成含多巴环二肽的路线,即采用常见易得的N-Fmoc保护的氨基酸与多巴甲酯中间体H-DOPA(Acetonide)-OM...; 关键词：左旋多巴环二肽二酮哌嗪缩丙酮自由基清除

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

L-DOPA

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

L-DOPA

检索结果分析

下载全文

用户登录

高级检索检索式检索