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Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats: 《Neural Regeneration Research》2025年第4期1164-1177,共14页Pengfei Wang Yuewei Bi Min Li Jiazhi Chen Zhuyong Wang Huantao Wen Ming Zhou Minjie Luo Wangming Zhang; supported by the National Natural Science Foundation of China,No.82071254(to WZ).; Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Cu...; 关键词：aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials NEUROMODULATION Parkinson’s disease primary motor cortex

Review of Key Technologies for Developing Personalized Lower Limb Rehabilitative Exoskeleton Robots: 《Journal of Shanghai Jiaotong university(Science)》2024年第1期16-28,共13页陶璟周振欢; the National Natural Science Foundation of China(No.51875358)。; Rehabilitative training and assistance to daily living activities play critical roles in improving the life quality of lower limb dyskinesia patients and older people with motor function degeneration.Lower limb reha-b...; 关键词：powered exoskeleton lower limb dyskinesia REHABILITATION PERSONALIZATION product-service system

A retrospective cohort study to examine the association between the persistence of abdominal pain after cholecystectomy and ejection fraction on HIDA scan in patients with biliary dyskinesia: 《iLIVER》2023年第4期208-213,共6页Baldeep Kaur Mann Janpreet Singh Bhandohal Ishaan Kalha Brian Jean; Background and aims:The persistence of pain in patients who underwent cholecystectomy primarily for biliary dyskinesia has been associated with gall bladder ejection fraction(GBEF)found on hepatobiliary iminodiacetic ...; 关键词：Post-cholecystectomy syndrome Biliary dyskinesia DYSKINESIA Gall bladder ejection fraction PCS HIDA CHOLECYSTECTOMY

Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels被引量：1: 《Research》2023年第4期739-753,共15页Chu Tong Peng-Xiang Min Qian Zhang Ru-Xin Gu Yao-Hai Wen Yi Shi Yu-Huan Bao Xiang Chen Yi-Xuan Zhang Xing-Feng Mao Hao-Yang Yuan Xiu-Xiu Liu Takuya Sasaki Li Zhang Feng Han Ying-Mei Lu; This work was supported by the National Key Research and Development Program of China(2022YFE0108600);the State Key Program of National Natural Science Foundations of China(81930103);the National Natural Science Foundations of China(81973300,82104162,and 82171249).; Disturbance of the cholinergic system plays a crucial role in the pathological progression of neurological diseases that cause dyskinesia-like behaviors.However,the molecular mechanisms underlying this disturbance rem...; 关键词：CDK5 NEURON CDK5

The Dynamics of Dopamine D_(2) Receptor-Expressing Striatal Neurons and the Downstream Circuit Underlying L-Dopa-Induced Dyskinesia in Rats: 《Neuroscience Bulletin》2023年第9期1411-1425,共15页Kuncheng Liu Miaomiao Song Shasha Gao Lu Yao Li Zhang Jie Feng Ling Wang Rui Gao Yong Wang; This work was supported by the National Natural Science Foundation of China(81671109,82071526,and 82071433);the Natural Science Foundation of Shaanxi Province(2021JQ-417).; L-dopa(l-3,4-dihydroxyphenylalanine)-induced dyskinesia(LID)is a debilitating complication of dopamine replacement therapy for Parkinson’s disease.The potential contribution of striatal D_(2) receptor(D2R)-positive n...; 关键词：LEVODOPA DYSKINESIA Parkinson's disease D_(2) RECEPTOR Fiber photometry OPTOGENETICS

Impact of smoking on nasal mucociliary clearance time in Kano metropolis,Nigeria: 《World Journal of Otorhinolaryngology-Head and Neck Surgery》2023年第1期53-58,共6页Ahmad Mahmud Abubakar D.Salisu Emmanuel S.Kolo Muhammad G.Hasheem Nafisatu Bello-Muhammad Ahmad R.Tukur Yasir J.Nuhu Rabiu I.Jalo; Background:Mucociliary clearance is an important defense mechanism in human upper and lower respiratory airways.Impairment of this process by certain conditions such as cigarette smoking can predispose to chronic infe...; 关键词：ciliary dyskinesia mucociliary clearance saccharin test SMOKING

Early-onset ophthalmoplegia,cervical dyskinesia,and lower extremity weakness due to partial deletion of chromosome 16:A case report: 《World Journal of Clinical Cases》2022年第26期9332-9339,共8页Min Xu Jiao Jiang Yan He Wei-Yue Gu Bo Jin; BACKGROUND We explored the genotype-phenotype correlation of the novel deletion 16p13.2p12.3 in an 8-year-old child with progressive total ophthalmoplegia,cervical dyskinesia,and lower limb weakness by comparing the p...; 关键词：Cervical dyskinesia Copy number variation Lower limbs weakness OPHTHALMOPLEGIA Whole-exome sequencing Case report

Effects of Interactive Dynamic Scalp Acupuncture on Motor Function and Gait of Lower Limbs after Stroke:A Multicenter,Randomized,Controlled Clinical Trial被引量：12: 《Chinese Journal of Integrative Medicine》2022年第6期483-491,共9页ZHANG Shao-hua WANG Yu-long ZHANG Chun-xia ZHANG Chun-ping XIAO Peng LI Qian-feng LIANG Wei-rong PAN Xiao-hua ZHOU Ming-chao; Supported by Medical Research Fund of Guangdong,China(No.A2020448);Special Fund Support Project for Industrial Development in Dapeng New District,Shenzhen of Guangdong Province,China(No.YL202001-16);Medical and Health Research Fund Project of Medical and Health Group in Dapeng New District,Shenzhen,Guangdong Province,China(No.2019JTYM003,2019JTYM004)。; Objective:To evaluate the effects of interactive dynamic scalp acupuncture(IDSA),simple combination therapy(SCT),and traditional scalp acupuncture(TSA)on motor function and gait of the lower limbs in post-stroke hemip...; 关键词：interactive dynamic scalp acupuncture STROKE DYSKINESIA lower extremity motor ability GAIT self-care capability randomized controlled clinical trial

Multivariable clinical-genetic model for predicting dyskinesia in early-onset Parkinson’s disease: 《Translational Neurodegeneration》2021年第3期343-345,共3页Yong-Ping Chen Ru-Wei Ou Xiao-Jing Gu Ling-Yu Zhang Bei Cao Yan-Bing Hou Kun-Cheng Liu Jun-Yu Lin Qian-Qian Wei Bi Zhao Ying Wu Hui-Fang Shang; This study was supported by the National Key Research and Development Program of China(2018YFC1312001 and 2016YFC0901504);the National Natural Science Foundation of China(81971188);the 1.3.5 project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYJC18038,ZYJC18003 and 2019HXFH046).; Main text The levodopa-induced dyskinesias(LIDs)in Parkinson’disease(PD)patients during levodopa treatment can lead to significant disability.Accumulative evidence has suggested that the younger the age of onset,the ...; 关键词：CLINICAL DOPAMINE YOUNGER

Effects of bilateral subthalamic nucleus deep brain stimulation on motor symptoms in Parkinson’s disease: a retrospective cohort study: 《Neural Regeneration Research》2021年第5期905-909,共5页Guo-Xiong Cheng Shu-Bin Yin Ying-Hao Yang Yuan-Hu Hu Chih-Yang Huang Qian-Ming Yao Wei-Jen Ting; This study was supported in part by the Guangdong Medical Science Foundation of China,Nos.A2013252(to GXC),C2013024(to QMY);Guangdong Science and Technology Foundation of China,No.20120318018(to QMY).; Deep brain stimulation of the bilateral subthalamic nucleus(STN)is a therapeutic option for patients with Parkinson’s disease(PD)in whom medical therapies have been ineffective.This retrospective cohort study analyze...; 关键词：clinical trial deep brain stimulation dopamine DYSKINESIA LEVODOPA long-term follow-up neurological function Parkinson’s disease THALAMUS UPDRS

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