ANTIBODY-TARGETED

作品数：2被引量：7H指数：1
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相关期刊：《World Journal of Gastroenterology》《World Journal of Hepatology》更多>>
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Construction of non-covalent single-chain Fv dimers for hepatocellular carcinoma and their biological functions
《World Journal of Hepatology》2010年第5期185-191,共7页Cai-Qun Bie,Department of Gastroenterology,Shenzhen Shajing Affiliated Hospital of Guangzhou Medical University,Shenzhen 518104,Guangdong Province,China Dong-Hua Yang,Xu-Jing Liang,Shao-Hui Tang,Department of Gastroenterology,the First Affiliated Hospital of Jinan University,Guangzhou 510630,Guangdong Province,China 
Supported by Guangdong Province Science and Technology Tackling Key Project,No.2006B19901014;the New Drug Project of Guangzhou Committee of Science and Technology,No.2004Z3-E4121
AIM:To create new diabodies with improved binding activity to antigen of the variable light-variable heavy (VH-VL)oriented single-chain Fv dimers genes(scFv). METHODS:The linker between VH and VL genes was shortened t...
关键词：DIABODY ANTIBODY-TARGETED SPECIFICITY AFFINITY Stability 
Disulfide-stabilized single-chain antibody-targeted superantigen: Construction of a prokaryotic expression system and its functional analysis被引量：7
《World Journal of Gastroenterology》2005年第31期4899-4903,共5页Jian-Li Wang Yu-Ling Zheng RU Ma Bao-Li Wang Ai-Guang Guo Yong-Qiang Jiang 
Supported by the National Natural Science Foundation of China,No. 30271478
AIM: To construct the expression vector of B3 (scdsFv)-SEA (D227A) and to identify its binding and cytotoxic ability to B3 antigen positive carcinoma cell lines.METHODS: This fusion protein was produced by a bacterial...
关键词：B3 monoclonal antibody Single-chain disulfide-stabilized Fv SUPERANTIGEN 
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