云南高校图书馆联盟文献共享服务平台- SUPERANTIGEN

SUPERANTIGEN: 作品数：20被引量：30H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：吴礼襄更多>>; 相关机构：广州医科大学更多>>; 相关期刊：《免疫学杂志》《Journal of Microbiology and Immunology》《Open Journal of Immunology》《China Medical Abstracts(Internal Medicine)》更多>>; 相关基金：国家自然科学基金更多>>

A non-viral gene therapy for melanoma by staphylococcal enterotoxin A: 《Chinese Chemical Letters》2024年第5期325-329,共5页Ling Yang Min Ren Jie Wang Liming He Shanshan Wu Shuai Yang Wei Zhao Hao Cheng Xiaoming Zhou Maling Gou; supported by the National Natural Science Foundation(No.82073363);the Sichuan Science and Technology Program(Nos.2020YFQ0059,2022YFQ0004);the Natural Science Foundation of Sichuan Province(No.2022NSFSC1304).; Staphylococcal enterotoxin A(SEA)derived from Staphylococcus aureus,as a superantigen,shows potential for cancer immunotherapy,but systemic immunotoxicity restricts its clinical application.Targeted delivery of SEA to...; 关键词：Gene therapy SUPERANTIGEN MELANOMA Staphylococcal enterotoxins A Immunotherapyene therapy

Update on molecular diversity and multipathogenicity of staphylococcal superantigen toxins被引量：1: 《Animal Diseases》2021年第2期69-83,共15页Dongliang Hu Shaowen Li Rendong Fang Ono K.Hisaya; This study was supported in part by the JSPS KAKENHI Grant numbers 19590438(D.H.);21590475(D.H.);24590516(D.H.);16H05030(D.H.).; Staphylococcal superantigen(SAg)toxins are the most notable virulence factors associated with Staphylococcus aureus,which is a pathogen associated with serious community and hospital acquired infections in humans and ...; 关键词：Staphylococcus aureus SUPERANTIGEN ENTEROTOXIN Pathogenecity Food poisoning Infeaion

Investigation of <i>Streptococcus pyogenes</i>Carriage in Population Vulnerable to Scarlet Fever during 2015-2017 in Shanghai, China: 《Journal of Biosciences and Medicines》2018年第11期89-97,共9页Mingliang Chen Chi Zhang Dechuan Kong Hao Pan Xi Zhang Min Chen; This study aimed to investigate the carriage of Streptococcus pyogenes in population vulnerable to scarlet fever and to compare their genotypic characterization between different age groups. Pharyngeal swabs were coll...; 关键词：SCARLET Fever CARRIAGE Rate Child EMM type SUPERANTIGEN

Colonization by Superantigen Producing Staphylococcus aureus in Mice Enhances the Capacity to Develop Oral Tolerance: 《Open Journal of Immunology》2016年第3期79-92,共14页Anna Stern Erika Lindberg Forough L. Nowrouzian Agnes E. Wold Sofia Östman; Microbial stimulation in early childhood may be necessary for proper maturation of the immune system. Infants colonized with Staphylococcus aureus have low risk of developing food allergy. Neonatal exposure to staphyl...; 关键词：Oral Tolerance SUPERANTIGEN Staphylococcus aureus

Study on the relationship between M protein gene-types and superantigen genes of Group A Streptococcus pyogenes strains isolated from scarlet fever patients in Beijing: 《China Medical Abstracts(Internal Medicine)》2016年第1期16-,共1页吴双胜; Objective To explore the relationship between superantigen and M protein gene(emm)-types genes of Group A Streptococcus pyogenes(GAS)isolated from patients with scarlet fever in Beijing from May 2012 to July 2013.Meth...; 关键词：STREPTOCOCCUS ISOLATES possessed EPIDEMIC PROPORTION

Stimulation of staphylococcal enterotoxin A combined with PML-RARα peptide on the specifical T-cells against NB4 cell line: 《The Chinese-German Journal of Clinical Oncology》2009年第3期175-177,共3页Chen Lin Xue Bai Lijian Yang Shaohua Chen B. N. Selvakumar Yangqiu Li; Supported by grants from the Science and Technology Commission of Guangdong Province (No.06025169,No.2005B50301016);the Key Laboratory of Pathophysiology of Jinan University; Objective： To investigate the effects of staphyococcal enterotoxin A （SEA） on the cytotoxicity of T cells stimulated by PML-RARa peptide in vitro. Methods： Peripheral blood mononuclear cells （MNC） from healthy d...; 关键词：SUPERANTIGEN PML-RARa pepUde NB4 cells T cells

Response of T cells in vivo Induced by Repeated Superantigen Treatments at Different Time Intervals: 《Acta Biochimica et Biophysica Sinica》2007年第7期467-474,共8页Yang HUANG Yanfang SUI Xiumin ZHANG Shaoyan SI Wei GE Peizhen HU Xia LI Bin MA; This study was supported by a grant from the National Natural Science Foundation of China （No. 30271464）; We have investigated the response of T cells to staphylococcal enterotoxin A （SEA） injections in vivo. We found that a single injection of SEA with an optimal dose of 10μg increased the expression of both CD4 and C...; 关键词：RESPONSE T cell SUPERANTIGEN time interval

A Possible Association of Staphylococcus Enterotoxin B-induced Asthma and Sinusitis: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第1期63-67,共5页刘涛孔维佳杨平常王斌全; In order to gain insight into a possible association between chronic sinusitis and asthma, 85 patients with sinusitis and asthma underwent functional endoscopic sinus surgical treatment and serum antibodies and cytoki...; 关键词：ASTHMA SINUSITIS SUPERANTIGEN Staphylococcus aureus endoscopic sinus surgery IL-4 IFN-γ

Anti-tumor Effect and Mechanism of SEA-Fab’ Coupled Protein on Gastric Tumor: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2005年第5期549-551,共3页舒晓刚王国斌; Summary： The anti-tumor effect and mechanism of SEA-Fab＇ coupled protein on gastric tumor was studied. The target cell Walke-256 was treated with SEA-Fab＇ synthesized chemically or SEA respectively for 24 h, 36 h o...; 关键词：SUPERANTIGEN SEA-Fab＇ gastric tumor APOPTOSIS anti-tumor effect

Disulfide-stabilized single-chain antibody-targeted superantigen: Construction of a prokaryotic expression system and its functional analysis被引量：7: 《World Journal of Gastroenterology》2005年第31期4899-4903,共5页Jian-Li Wang Yu-Ling Zheng RU Ma Bao-Li Wang Ai-Guang Guo Yong-Qiang Jiang; Supported by the National Natural Science Foundation of China,No. 30271478; AIM: To construct the expression vector of B3 (scdsFv)-SEA (D227A) and to identify its binding and cytotoxic ability to B3 antigen positive carcinoma cell lines.METHODS: This fusion protein was produced by a bacterial...; 关键词：B3 monoclonal antibody Single-chain disulfide-stabilized Fv SUPERANTIGEN

SUPERANTIGEN