BISPHOSPHONATES

作品数:42被引量:85H指数:5
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相关领域:医药卫生更多>>
相关作者:严世贵张旭陈中王跃封志云更多>>
相关机构:浙江大学医学院附属第二医院安徽医科大学浙江大学医学院附属第一医院重庆市中山医院更多>>
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相关基金:国家自然科学基金更多>>
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Prevalence of Osteonecrosis of the Jaw (ONJ) in Patients Exposed to Bisphosphonates at a University Hospital in Marrakech
《Open Journal of Epidemiology》2025年第1期65-75,共11页Aicha Oubbaih Mouad Mouhtaram Youness Moutaabid Bouchra Badre Samira Bellemkhannate Nadia Zaim 
Background: Bisphosphonates are compounds similar to inorganic pyrophosphates, with anti-angiogenic, anti-inflammatory, anti-bone resorption, and antitumor effects. They are used to prevent bone metastases in cancer a...
关键词:Bisphosphonate-Related Osteonecrosis of the Jaw BISPHOSPHONATES Osteonecrosis of the Jaw PREVALENCE 
Prevalence and Risk Factors of Osteonecrosis of the Jaw in Patients with Bisphosphonate Exposure in Casablanca, Morocco: An Observational Study
《Open Journal of Epidemiology》2024年第3期533-545,共13页Aicha Oubbaih Soukaina Remch Meryem Reggab Bouchra Badre Samira Bellemkhannate Nadia Zaim 
Objective: To study the prevalence of bisphosphonate-related osteonecrosis of the jaw (BRONJ) and to determine the risk factors associated with the occurrence of this pathology. Method: An observational retrospective ...
关键词:Bisphosphonate-Related Osteonecrosis of the Jaw BISPHOSPHONATES Osteonecrosis of the Jaw PREVALENCE 
Three cases of uncommon medication-associated osteonecrosis of temporal bone
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第3期237-240,共4页Hunter VanDolah Jason R.Crossley H.Jeffrey Kim 
Introduction:Medication-related osteonecrosis of the temporal bone is rare and has been reported to be associated with the use of anti-resorptive and biologic agents.Here,we present the first case of tyrosine-kinase i...
关键词:BISPHOSPHONATES DENOSUMAB external auditory canal imatinib medication-related osteonecrosis OSTEONECROSIS temporal bone tyrosine-kinase Inhibitors 
Role of bisphosphonates in osteoporosis caused by adult growth hormone deficiency被引量:1
《中南大学学报(医学版)》2024年第6期839-847,共9页CHENG Zhiling LI Jie CHEN Zhongpei REN Wei 
This work was supported by the Special Project of Performance Incentive and Guidance for Scientific Research Institutions of Chongqing,China (jxyn2022-5)。
In recent years,growth hormone and insulin-like growth factors have become key regulators of bone metabolism and remodeling,crucial for maintaining healthy bone mass throughout life.Studies have shown that adult growt...
关键词:growth hormone adult growth hormone deficiency OSTEOPOROSIS BISPHOSPHONATES insulin-like growth factor 1 SKELETON 
Impact of bisphosphonate treatment on bone mineral density after kidney transplant
《World Journal of Transplantation》2024年第3期102-109,共8页Georgia Andriana Georgopoulou Marios Papasotiriou Theodoros Ntrinias Eirini Savvidaki Dimitrios S Goumenos Evangelos Papachristou 
BACKGROUND Mineral bone disease is associated with chronic kidney disease and persists after kidney transplantation.Immunosuppressive treatment contributes to the patho-genesis of this disease.Bisphosphonate treatment...
关键词:Mineral and bone disorders Chronic kidney disease Kidney transplant recipients BISPHOSPHONATES Bone mineral density 
The interplay of drug therapeutics and immune responses to SARS-CoV-2被引量:1
《Cellular & Molecular Immunology》2024年第2期197-200,共4页Valeria Fumagalli Matteo Iannacone 
supported by the European Research Council(ERC)Consolidator Grant 725038;the ERC Proof of Concept Grants 957502 and 101138728;the Italian Association for Cancer Research(AIRC)Grants 19891 and 22737;the Italian Ministry for University and Research Grants PE00000007(INF-ACT)and PRIN(2022FMESXL);a Funded Research Agreement from Asher Biotherapeutics and VIR Biotechnology.
The SARS-CoV-2 pandemic has necessitated rapid therapeutic and preventative responses.While vaccines form the frontline of defense,antiviral treatments such as nirmatrelvir have emerged as vital adjunctive measures,pa...
关键词:SARS-CoV-2 Nirmatrelvir BISPHOSPHONATES Adaptive immunity Drug repurposing 
Current concepts in the management of bisphosphonate associated atypical femoral fractures被引量:4
《World Journal of Orthopedics》2021年第9期660-671,共12页Branavan Rudran Jonathan Super Rajan Jandoo Victor Babu Soosai Nathan Edward Ibrahim Anatole Vilhelm Wiik 
Bisphosphonates are a class of drugs used as the mainstay of treatment for osteoporosis.Bisphosphonates function by binding to hydroxyapatite,and subsequently targeting osteoclasts by altering their ability to resorb ...
关键词:BISPHOSPHONATES Atypical fracture Surgical fixation Atypical femoral fracture OSTEOPOROSIS 
Determination of bisphosphonates anti-resorptive properties based on three forms of ceramic materials: Sorption and release process evaluation
《Journal of Pharmaceutical Analysis》2021年第3期364-373,共10页Monika Zielinska Ewa Chmielewska Tomasz Buchwald Adam Voelkel PawełKafarski 
supported by the Ministry of Science and Higher Education grants and subsidy of the Ministry of Science and Higher Education。
There is a strong need to search for more effective compounds with bone anti-resorptive properties,which will cause fewer complications than commonly used bisphosphonates. To achieve this goal, it is necessary to sear...
关键词:Monolithic column Polymer composites BISPHOSPHONATES Hydroxyapatite coatings Hydroxyapatite composite 
Vigorous Endosteal Reaming across Fracture Site to Aid Union in Atypical Femur Fractures
《Open Journal of Orthopedics》2020年第12期412-418,共7页Sanjay Agarwala Mayank Vijayvargiya Prashant Pandey 
Background: Bisphosphonate abuse is associated with atypical femur fractures, which despite different fixation methods have increased non-union, delayed union, and re-oper...
关键词:Atypical Femur Fracture Vigorous Reaming BISPHOSPHONATES Intramedullary Nail 
Hypercalcaemia after treatment with denosumab in children:bisphosphonates as an option for therapy and prevention?被引量:2
《World Journal of Pediatrics》2020年第5期520-527,共8页Carmen Sydlik Hans Roland Dürr Susanne Bechtold-Dalla Pozza Claudia Weiβenbacher Julia Roeb Heinrich Schmidt 
Background Pharmacologic options for treatment of osteolytic diseases especially in children are limited.Although not licensed for use,denosumab,a fully humanized antibody to RANKL,is used in children with good effect...
关键词:Aneurysmatic bone cyst BISPHOSPHONATES Calcium homeostasis DENOSUMAB Giant cell tumor of the bone 
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