STRUCTURE-ACTIVITY

作品数：72被引量：82H指数：5
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相关作者：金春梅肖娟郭淑晶周鑫王永瑞更多>>
相关机构：延边大学北京大学广东医学院南京药物研究所更多>>
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Structure-activity relationship of endomorphins and their analogs
《Chinese Science Bulletin》2001年第13期1096-1100,共5页HUO Xiaofeng WU Ming REN Weihua WANG Rui CHAN Albert S.C. 
This work was supported by the National Natural Science Foundation of China (Grant No. 20072014); the Teaching and Research Award Program for Outstanding Young Teachers in Higher Education Institutions of MOE of China; Gansu Provincial Key Science and
To study the structure-activity relationship of endomorphins (EMs), the action of opioid receptor binding (AORB), analgesic activity and vasodilator effects of EMs and their eight analogs were investigated, which were...
关键词：ENDOMORPHINS STRUCTURE-ACTIVITY relationship action of OPIOID receptor binding ANALGESIA VASODILATATION mechanism of inactivation. 
Synthesis, structure-activity relationship of nociceptin and its fragments被引量：3
《Chinese Science Bulletin》1999年第18期1655-1659,共5页Shouliang Dong Tao Wang Qiang Chen Rui Wang 
Nociceptin (NC) and its 4 fragments have been synthesized by solid phase peptide synthesis. Their hypotensive activity and mechanism, MVD assay and structure-activity relationship have been investigated. Results show ...
关键词：NOCICEPTIN solid phase PEPTIDE SYNTHESIS HYPOTENSIVE activity STRUCTURE-ACTIVITY relationship. 
Analysis of aromatic sulfur-containing compounds based on free-Wilson method被引量：2
《Chinese Science Bulletin》1995年第19期1621-1624,共4页洪晖 韩朔睽 王连生 赵元慧 邹公伟 张正 
Project supported by the National Natural Science Foundation of China.
In the study of quantitative structure-activity relationships (QSARs), Hansch’s linear free-energy relationships (LFERs) are the most commonly used. However, LFERs have many limitations. Free-Wilson method has its sp...
关键词：STRUCTURE-ACTIVITY free-Wilson method. 
Quantitative Structure-Activity Relationships for Substituted Aromatic Compounds
《Chinese Science Bulletin》1994年第19期1612-1615,共4页何艺兵 刘征涛 赵元慧 王连生 
Project supported by the National Natural Science Foundation of China.
The use of quantitative structure-activity relationships (QSARs) started with the research into drugs and pesticides. It can be applied to predicting biological activity of new organic compounds from their molecular s...
关键词：STRUCTURE-ACTIVITY energy of highest occupied molecular ORBITAL octanol/water PARTITION coefficient. 
Biological Activity of Brassinosteroids and Relationship of Structure to Plant Growth Promoting Effects
《Chinese Science Bulletin》1994年第18期1573-1577,共5页王玉琴 罗文华 徐如涓 赵毓桔 周维善 黄良富 沈季铭 
Brassinolide (BR) is a new potent growth promoting steroid substance which was first isolated from rape pollen by Grove et al. in 1979. Since then a number of BR analogues, such as homobrassinolide 2 and epibrassinoli...
关键词：brassinosteroids  rice-lamina-inclination TEST structure-activity-relationship. 
Quantitative Structure-Activity Relationship for Some Substituted Aromatic Compounds被引量：1
《Chinese Science Bulletin》1994年第13期1092-1095,共4页张育红 于红霞 韩朔睽 赵元慧 王连生 
National Natural Science Foundation of China
In recent years, since thousands of new chemicals have been produced and put into the environment, it is important for us to screen the chemicals which have potential toxicity. So QSAR (quantitative structure-activity...
关键词：STRUCTURE-ACTIVITY n-octanol/water PARTITION COEFFICIENT non-dispersive force factor correlation equation. 
Quantitative Structure-Activity Relationships of Organic Pollutants
《Chinese Science Bulletin》1993年第16期1364-1367,共4页赵元慧 王连生 高鸿 
Project supported by the National Natural Science Foundation of China.
QSARs (Quantitative structure-activity relationships) can provide correlations between the toxicity of a chemical and the physicochemical descriptors of the chemical. They can stimulate the development of toxicity dat...
关键词：STRUCTURE-ACTIVITY toxidty MECHANISM CORRELATION EQUATION 
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