PYRIMETHAMINE

作品数：14被引量：2H指数：1
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Uptake of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine (IPTp-SP) in Pregnancy and Associated Factors in a Malaria Endemic Setting of Sub-Saharan Africa
《Advances in Infectious Diseases》2024年第4期776-792,共17页Marcelus U. Ajonina Irene U. Ajonina-Ekoti John Ngulefac Sharlot E. Fosah Kenric B. Ware Clorinda M. Nche Carine K. Nfor Martin Ayim Tobias O. Apinjoh 
Introduction: Malaria in pregnancy (MiP) is a public health issue that poses risks to maternal and fetal health. Although the World Health Organization recommends intermittent preventive treatment with sulfadoxine-pyr...
关键词：PREGNANCY Intermittent Preventive Treatment Sulphadoxine Pyrimethamine Optimal Uptake Bonassama District Hospital 
Prevalence and Individual-Level Determinants of Uptake of Three or More Doses of Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Busia County, Kenya
《Open Journal of Epidemiology》2024年第3期405-418,共14页Anne Nduta Miatu Betsy Rono Cheriro Kamija Samuel Phiri 
Background: Malaria in pregnancy causes maternal anemia, low birth weight, intrauterine growth retardation, and preterm deliveries. In malaria-endemic regions in Kenya, percentage of pregnant women hospitalized with m...
关键词：Malaria in Pregnancy Antenatal Clinic Intermittent Prevention of Malaria in Pregnancy DOSAGE UPTAKE Sulphadoxine-Pyrimethamine and Individual Level Factors 
Pyrimethamine upregulates BNIP3 to interfere SNARE-mediated autophagosome-lysosomal fusion in hepatocellular carcinoma被引量：1
《Journal of Pharmaceutical Analysis》2024年第2期211-224,共14页Jingjing Wang Qi Su Kun Chen Qing Wu Jiayan Ren Wenjuan Tang Yu Hu Zeren Zhu Cheng Cheng Kaihui Tu Huaizhen He Yanmin Zhang 
supported by the National Natural Science Foundation of China(Grant No:81903643);the“Young Talent Support Plan”of Xi'an Jiaotong University,the Shaanxi Province Science and Technology Development Plan Project(Grant No.:2022ZDLSF05-05);the Project of Shaanxi Provincial Administration of Traditional Chinese Medicine(Project No.:2021-03-ZZ-002);the Shaanxi Province Science Fund for Distinguished Young Scholars(Grant No:2023-JC-JQ-59).
Hepatocellular carcinoma (HCC) is one of the most common tumor types and remains a major clinical challenge. Increasing evidence has revealed that mitophagy inhibitors can enhance the effect of chemotherapy on HCC. Ho...
关键词：PYRIMETHAMINE BNIP3 SNARE Autophagosome-lysosome fusion Hepatocellular carcinoma Sorafenib 
Vibrational Spectroscopic Investigations, Electronic Properties, Molecular Structure and Quantum Mechanical Study of an Antifolate Drug: Pyrimethamine
《Computational Chemistry》2022年第4期157-185,共29页Pélagie Manwal A Mekoung Bel Youssouf G. Mountessou Maraf B. Mbah Martin Signe Auguste Abouem A Zintchem Charles P. N. Nanseu Ibrahim N. Mbouombouo 
The computational modelling supported by experimental results can explain the molecular structure, vibrational assignments, reactive sites and several structural properties. In this context, the spectroscopic (FT-IR, ...
关键词：Electronic Property NMR PYRIMETHAMINE Vibrational Spectrum 
Effectiveness of non-pyrimethamine-based regimens for toxoplasma encephalitis:A systematic and meta-synthesis study
《Asian Pacific Journal of Tropical Medicine》2022年第3期106-113,共8页David Susanto Arthur H.P.Mawuntu Finny Warouw Windy M.V.Wariki 
Objective:To examine the differences in effectiveness and side effects between pyrimethamine-based and non-pyrimethamine-based regimens for toxoplasma encephalitis since the availability of pyrimethamine in Indonesia ...
关键词：Toxoplasma encephalitis Alternative treatment Without pyrimethamine Systematic review META-SYNTHESIS 
Development of a Method for Identification and Quantification of Sulfadiazine and Pyrimethamine in Serum of Congenital Toxoplasmosis Pediatric Patients
《Pharmacology & Pharmacy》2021年第8期155-166,共12页Maria Elena Marson Fleitas Ulises Pérez Montilla Carlos Prospitti Anabela Altcheh Jaime Moroni Samanta Moscatelli Guillermo García Bournissen Facundo Mastrantonio Guido 
Infection with Toxoplasma gondii, is one of the most widespread...
关键词：TOXOPLASMOSIS BIOANALYTICS Pediatric Pharmacology Therapeutic Drug Monitoring Neglected Diseases 
Knowledge and Perceived Barriers towards Intermittent Prevention of Malaria in Pregnancy: A Cross-Sectional Study
《Open Journal of Internal Medicine》2021年第1期27-38,共12页Frank Bediako Agyei Gideon Dzando Anthony B. Donyi Elisha A. Nonoh Rebecca Dordunu Catherine Konadu Opoku 
Background: Intermittent prevention of malaria is a key strategy adopted globally to ensure the wellbeing of pregnant women. By extension, these strategies enhance the healthy development of the fet...
关键词：MALARIA Intermittent Prevention and Treatment (IPTp) Insecticide Treated Nets (ITNs) Antenatal Care Sulphadoxine Pyrimethamine (SP) 
High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria
《Infectious Diseases of Poverty》2020年第4期152-153,共2页Hong Quan Uche Igbasi Wellington Oyibo Sunday Omilabu Shen-Bo Chen Hai-Mo Shen Chukwuma Okolie Jun-Hu Chen Xiao-Nong Zhou 
Background Plasmodium falciparum-resistance to sulphadoxine-pyrimethamine(SP)has been largely reported among pregnant women.However,the profile of resistance markers to SP dihydrofolate reductase(dhfr)and dihydroptero...
关键词：Plasmodium falciparum Antimalarial drug resistance Sulphadoxine-pyrimethamine Dihydrofolate reductase Dihydropteroate synthase 
Intermittent Preventive Treatment in Pregnancy with Sulphadoxine-Pyrimethamine Does Not Have Effect on Maternal Hemoglobin at Delivery and Birth Weight in Kisangani, Democratic Republic of Congo
《Journal of Biosciences and Medicines》2019年第12期168-180,共13页Labama Otuli Noel Bosenge Nguma Jean-Didier Maindo Alongo Mike-Antoine Losimba Likwela Joris Manga Okenge Jean-Pascal 
Faculty of Medicine and Pharmacy of University of Kisangani
Background: The consequences of malaria during pregnancy are different regarding local conditions of malaria transmission. In stable malaria areas, the main complications are maternal anaemia and fetal growth restrict...
关键词：Intermittent Preventive Treatment in Pregnancy Sulphadoxine-Pyrimethamine Pregnancy-Associated Malaria Maternal Anaemia at Delivery Low Birth Weight Kisangani 
Comprehension of Risk Factors of Malaria during Pregnancy among Pregnant Women Attending Antenatal Care in Malawi
《Open Journal of Nursing》2014年第12期896-905,共10页Vivian Mpanga Alfred Maluwa Ursula Kafulafula Mercy Pindani Kaye Bultemeier 
A study was conducted to determine the comprehension of pregnant women on malaria risk factors during pregnancy. Comprehension of Malaria risks is important to ensure compliance to prevention methods and treatment by ...
关键词：Direct Observation TREATMENT (DoT) Intermittent Prevention TREATMENT (IPT) MALARIA Risk in PREGNANCY Adherence to Anti-Malaria CHEMOPROPHYLAXIS Sulphadoxine-Pyrimethamine (SP) MALARIA PARASITE 
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