SPERMIOGENESIS

作品数:35被引量:148H指数:4
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相关领域:生物学更多>>
相关作者:侯聪聪杨万喜于虎虎向东方孙文佳更多>>
相关机构:浙江大学陕西师范大学中国科学院河北大学更多>>
相关期刊:《Journal of Animal Science and Biotechnology》《Journal of Ocean University of China》《Science China(Life Sciences)》《Asian Herpetological Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划陕西省自然科学基金更多>>
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Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis被引量:78
《Cell Research》2017年第10期1216-1230,共15页Zhen Lin Phillip J Hsu Xudong Xing Jianhuo Fang Zhike Lu Qin Zou Ke-Jia Zhang Xiao Zhang Yuchuan Zhou Teng Zhang Youcheng Zhang Wanlu Song Guifang Jia Xuerui Yang Chuan He Ming-Han Tong 
M-HT was supported by the Strategic Priority Research Pro- gram of the Chinese Academy of Sciences (XDB19000000), the Ministry of Science and Technology of China (2014CB943101), the National Key Research and Development Program of China (2016YFC1000600), SIBS foundation, the National Natural Science Foundation of China (31471401 and 31671553), the Science and Technology Commission of Shanghai Municipality (14140901502 and 14JC1407100). This work was also supported by NIH HG008688 (CH). CH is an investigator of the Howard Hughes Medical Institute. XY was supported by the National Natural Science Foundation of China (81472855 and 91540109), the Ministry of Science and Technology of China Grant (2016YFC0906001). We thank the Histology, Flow Cytometry and Vivarium services at SIBCB, and the Genome Sequencing and High-performance Computing services from the National Protein Science Facility (Beijing) at Tsinghua University.
Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells (SSCs) produce hap- loid spermatozoa. This highly specialized process is precisely controlled at the transcriptional, postt...
关键词:m6A RNA modification Mettl3 Mettll4 spermatogonial stem cell SPERMIOGENESIS 
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis被引量:44
《Cell Research》2014年第6期680-700,共21页Lan-Tao Gou Peng Dai Jian-Hua Yang Yuanchao Xue Yun-Ping Hu Yu Zhou Jun-Yan Kang Xin Wang Hairi Li Min-Min Hua Shuang Zhao Si-Da Hu Li-Gang Wu Hui-Juan Shi Yong Li Xiang-Dong Fu Liang-Hu Qu En-Duo Wang Mo-Fang Liu 
We thank Drs Narry Kim (Seoul National University, Korea) and Fatitima Gebauer (Centre for Genomic Regulation, Spain) for suggestions and critical comments on the manuscript; Drs Chen Chu, Junhao Li, and Xianghua Piao for experimental and bioinformatic assistance. This work was supported by grants from the Ministry of Science and Technology of China (2011CB811303, 2014CB964802, 2014CB943103, 2012CB910803), the National Natural Science Foundation of China (31325008, 91219306, 31270840, 31170754, 31300656), and Science and Technology Commission of Shanghai Municipality (13ZR 1464300).
Spermatogenesis in mammals is characterized by two waves of piRNA expression: one corresponds to classic piR- NAs responsible for silencing retrotransponsons and the second wave is predominantly derived from nontrans...
关键词:pachytene piRNAs MIWI CAF1 pi-RISC mRNA deadenylation ES 
Cytosolic Ca^(2+)as a multifunctional modulator is required for spermiogenesis in Ascaris suum
《Protein & Cell》2013年第6期456-466,共11页Yunlong Shang Lianwan Chen Zhiyu Liu Xia Wang Xuan Ma Long Miao 
the National Basic Research Program(973 Program)(Nos.2012CB945002 and 2010CB912303)and 31171337 from the Chinese government.
The dynamic polar polymers actin fi laments and microtu-bules are usually employed to provide the structural ba-sis for establishing cell polarity in most eukaryotic cells.Radially round and immotile spermatids from n...
关键词:SPERMIOGENESIS CA^(2+) major sperm protein Ascaris suum 
Transformation:how do nematode sperm become activated and crawl?被引量:4
《Protein & Cell》2012年第10期755-761,共7页Xuan Ma Yanmei Zhao Wei Sun Katsuya Shimabukuro Long Miao 
supported by the National Basic Research Program of China(Nos.2012CB94502,2010CB912303)(to L.M.);the National Natural Science Foundation of China(Grant Nos.31171337 and 30971648)(to L.M.);Grant Nos.30871226 and 31071180(to Y.Z.);supported by the Chinese Academy of Sciences 100-Talents Program.
Nematode sperm undergo a drastic physiological change during spermiogenesis(sperm activation).Unlike mammalian flagellated sperm,nematode sperm are amoeboid cells and their motility is driven by the dynamics of a cyto...
关键词:SPERMIOGENESIS major sperm protein sperm motility 
Analysis of gene expression patterns with cDNA microarray during late stage of spermatogenesis in mice被引量:3
《Chinese Science Bulletin》2002年第24期2075-2079,共5页YU Zuoren GUAN Jikui GE Yehua MA Jing GUO Rui LI Sai XUE Shepu HAN Daishu 
This work was supported by the National Key Basic Research Project (Grant No. G1999055901).
The differentiation process of round spermat-ids to spermatozoa during the late stage of spermatogenesis is called spermiogenesis. To explore spermiogenesis-related genes, cDNA microarray was used to study expression ...
关键词:SPERMATOGENESIS SPERMIOGENESIS CDNA MICROARRAY gene expression pattern RT-PCR. 
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