RECEPTOR-MEDIATED

作品数:48被引量:183H指数:7
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相关领域:医药卫生生物学更多>>
相关作者:袁玉民许德义孙亚锋胡国渊唐放鸣更多>>
相关机构:中国科学院徐州医学院南京医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划安徽省自然科学基金以色列科学基金更多>>
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Receptor-mediated mitophagy in yeast and mammalian systems被引量:34
《Cell Research》2014年第7期787-795,共9页Lei Liu Kaori Sakakibara Quan Chen Koji Okamoto 
Mitophagy, or mitochondria autophagy, plays a critical role in selective removal of damaged or unwanted mitochondria. Several protein receptors, including Atg32 in yeast, NIX/BNIP3L, BNIP3 and FUNDCI in mammalian syst...
关键词:MITOCHONDRIA quality control mitophagy receptor protein phosphorylation mitochondrial stress selective autophagy 
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils被引量:1
《Cell Research》2011年第10期1452-1469,共18页Nariman A B Balenga Elma Aflaki Julia Kargl Wolfgang Platzer Ralf Schroder Stefanie Blattermann Evi Kostenis Andrew J Brown Akos Heinemann Maria Waldhoer 
The directional migration of neutrophils towards inflammatory mediators, such as chemokines and cannabinoids, occurs via the activation of seven transmembrane G protein coupled receptors (7TM/GPCRs) and is a highly ...
关键词:GPR55 CB2R CHEMOTAXIS ROS production Rac2 CDC42 
PSD-95 regulates D1 dopamine receptor resensitization, but not receptor-mediated Gs-protein activation
《Cell Research》2009年第5期612-624,共13页Peihua Sun Jmgru Wang Welhua Gu Wei Cheng Guo-zhang Jin Eitan Friedman Jie Zheng Xuechu Zhen 
Acknowledgments We thank Dr Morgan Sheng (Harvard University, USA) for providing the cDNA construct for PSD-95. This study was sup- ported by the Natural Science Foundation of China (30770662, 30825042); Hi-Tech Research and Development Program of China (2007AA02Z163), National Basic Research Program (2009CB2200) to XZ, and funding from the National Institutes of Health (REY016754A) and the American Heart Association (0665201Y) to JZ. Part of this work was conducted in a facility constructed with support from Research Facilities Improvement Program Grant C06-RR-12088-01 from the National Center for Research Resources.
The present study aims to define the role of postsynaptic density (PSD)-95 in the regulation of dopamine (DA) receptor function. We found that PSD-95 physically associates with either D1 or D2 DA receptors in co-t...
关键词:PSD-95 dopamine receptor Gs-protein activation DESENSITIZATION recycling RESENSITIZATION 
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