This work is supported by the grants from National Institutes of Health(R01DK102619, R01DK118941, R01DK118805, and R0DK121548)。
Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease worldwide. It refers to a range of liver conditions affecting people who drink little or no alcohol. NAFLD comprises non-a...
Background:A high consumption of fructose leads to hepatic steatosis.About 20-30% of triglycerides are synthesized via de novo lipogenesis.Some studies showed that endoplasmic reticulum stress (ERS) is involved in ...