supported by Science and Technology Development Fund, Macao SAR (File Nos.: 0052/2018/A2 and 0077/2019/ A2);the National Natural Science Foundation of China (Grant No.: 61827819)
Endogenous ribonucleotides(RNs)and deoxyribonucleotides(dRNs)are important metabolites related to the pathogenesis of many diseases.In light of their physiological and pathological significances,a novel and sensitive ...
We performed density functional theory (DFT) calculations for ribonucleotides and active triphosphate metabolites of candidate drugs against Coronavirus disease 2019 (Covid-19). Frontier orbitals (highest occupied mol...
Natural Science Foundation Project of China(No.21405123);Fundamental Research Funds for the Central Universities(No.XDJK2019AC002)for the financial support。
Ribonucleotides are usually functioned as biomarkers to diagnose diseases and monitor the life activities in living organisms,and their discrimination is of great significance but challenging.Taking advantage of the u...