Science and Technology Planning Project of Guangdong Province,Grant/Award Number:2016A030303037 and 2017A070702014;Natural Science Foundation of Guangdong Province,(2018A030313307);National Natural Science Foundation of China,Grant/Award Number:81102358;GDAS Special Project of Science and Technology Development,Grant/Award Number:2017GDASCX-0107
Background : Cynomolgus disease models that are similar to the preclinical stage of human type 2 diabetes mellitus(T2 DM) were established by feeding middle-aged cynomolgus monkeys different high energy diets to study...