HETEROCYCLIC

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Intelligence Way from Eco-friendly Synthesis Strategy of New Heterocyclic Pyrazolic Carboxylic a-Amino Esters
《Chemical Research in Chinese Universities》2020年第6期1183-1189,共7页EI Houssine MABROUK Nadia ARROUSSE Adil KORCHI Mohammed LACHGAR Ahmad OUBAIR Abdelrhani ELACHQAR Mohamed JABHA Mohammed LACHKAR Fadoua El HAJJAJI Zakia RAIS Mustapha TALEB 
Supported by the Centre National de la Recherche Scientifique et Techniques,Rabat,Morocco(No.PROTARS D13/03).
The a-amino acid derivatives constitute a class of compounds of particular medicinal and synthetic attention and considerable interest has been devoted to their synthesis in recent years.In the present work,we develop...
关键词：a-Pyrazolyl amino ester Methyl a-azido glycinate N-benzoylated O-ALKYLATION DFT/B3LYP/6-31G(d p) 
Hydrogen Bonding Assembled 3D Supramolecular Structures Formed by 5-Amino-2,4,6-triiodoisophthalic Acid and TV-Heterocyclic Aromatic Ligands
《Chemical Research in Chinese Universities》2019年第5期806-811,共6页YU Wenli ZHANG Mingjuan LIU Kang YANG Yu WANG Lei 
Supported by the National Natural Science Foundation of China(Nos.51772162,21571112,51572136 and 21601103);the Scientific and Technical Development Project of Qingdao,China(No.17-1-1-78-jch) and the Taishan Scholars Program,Shangdong Province,China.
Three salts constructed by 5-amino-2,4,6-triiodoisophthalic acid(ATIPA) with N-heterocycles aromatic coformers such as pyridine tetrazolium, tetramethylpyraziiie and cyanuric acid were synthesized by slowing evaporati...
关键词：Hydrogen bond SUPRAMOLECULAR structure X-Ray diffraction N-Heterocyclic AROMATIC ligand 
Structure-based Design, Synthesis and Anti-influenza A Virus Activities of Substituted Phenyl-coupled Heterocyclic Ethylamide Derivatives
《Chemical Research in Chinese Universities》2015年第6期942-951,共10页WANG Yang LEI Fan LI Xiaolong HE Yi LI Jue QIU Rui WU Xueying HAI Li WU Yong 
A series of new substituted phenyl-coupled heterocyclic ethylamide derivatives was designed and synthe- sized as anti-influenza agents. In vitro anti-influenza A（A/PR/8/34 H1N1 strain） activities of these compounds ...
关键词：Influenza virus A Nucleoprotein inhibitor Ingavirin Nucleozin Biological evaluation 
Design,Synthesis and Antitumor Activity of Fluoroquinolone C3 Heterocyclic Bis-oxadiazole Methylsulfide Derivatives Derived from Levofloxacin被引量：3
《Chemical Research in Chinese Universities》2012年第6期980-984,共5页HU Guo-qlang WANG Guo-qiang DUAN Nan-nan WEN Xiao-yi CAO Tie-yao XIE Song-qiang HUANG Wen-long 
Supported by the National Natural Science Foundation of China(Nos.20872028,21072045)
To discover an efficient route for the shift from an antibacterial fluoroquinolone to an antitumor one based on the mechanistic similarities between targeting topoisomerases and the eukaryotic ones,two series of the t...
关键词：FLUOROQUINOLONE OXADIAZOLE ISOSTERE SULFIDE Piperazinium Antitumor activity 
Syntheses and Configuration Inversion of Substituted Oxazolines
《Chemical Research in Chinese Universities》2001年第3期271-275,共5页YANG Shao-rong HU Quan-yuan LIU Jun YANG Hui HU Xian-ming 
Supported by the Science and Technology Fundation of Wuhan City and Wuhan Red Heart K(Group) Co. Ltd.
The present paper covers the simply and highly stereoselective syntheses of (α-S, 4S)-2-dichloromethyl-4, 5-dihydro-α-(4-nitrophenyl)-4-oxazolemethanol (4a), (α-S, 4S)-2-methyl-4, 5-dihydro-α-(4-nitrophenyl)-4-oxa...
关键词：OXAZOLINE HETEROCYCLIC Configuration inversion 
Synthesis, Chemistry, and Applications of Heterocyclic Cage Compounds (V)
《Chemical Research in Chinese Universities》2001年第z1期132-,共1页WU Hsien-Jen 
The synthesis and chemistry of polycyclic of cage compounds have attracted considerable attention in recent years. The vast majority of the work reported in this area has dealt with carbocylic cage compounds. On the o...
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