CINOBUFAGIN

作品数：14被引量：14H指数：2
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相关领域：医药卫生更多>>
相关机构：西南医科大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Journal of Hainan Medical University》《Advances in Modern Oncology Research》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金广东省自然科学基金更多>>
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  • 期刊=Chemical Research in Chinese Universitiesx
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Synthesis and Cytotoxic Activities of Spin-labeled Derivatives of Cinobufagin
《Chemical Research in Chinese Universities》2017年第4期581-586,共6页GUO Jinhua TAN Bei YE Qingmei LIANG Guangping YI Min JIANG Renwang 
Supported by the National Natural Science Foundation of China（No. 81573315）, the Natural Science Foundation of Guangdong Province, China（No.2015A030313313）, the Guangzhou Industry-University Collaborative Innovation Major Projects, China（No.201508030016） and the Natural Science Foundation of Hainan Province, China（No.817307）.
Two series of novel spin-labeled derivatives of Cinobufagin（compounds 5 and 8a--8f in series 1 with five-membered ring nitroxyl free radical and compounds 6 and 9a-9f in series 2 with six-membered ring nitroxyl free ...
关键词：Cmobufagin Nitroxyl free radical Spin-labeled Cytotoxic activity 
Novel Cinobufagin Oxime Ether Derivatives as Potential Na＋/K＋-ATPase Inhibitors： Synthesis, Biological Screening and Molecular Docking被引量：1
《Chemical Research in Chinese Universities》2017年第3期378-383,共6页LIANG Guangping CHUNG Tseyu GUO Jinhua ZHANG Rongrong XU Wei TZEN Jason T.C JIANG Renwang 
Supported by the National Natural Science Foundation of China（No.81573315）, the Guangdong Natural Science Fund, China（No.2015A030313313） and the Guangzhou Industry-University Collaborative Innovation Major Projects, China（No. 201508030016）.
Some cinobufagin oxime ether derivatives as potential Na＋/K＋-ATPase inkibitors were synthesized by following the side chain of istaroxime. These compounds inhibit Na＋/K＋-ATPase in a dose-dependent manner. Compound...
关键词：CINOBUFAGIN Istaroxime Na＋/K＋-ATPase Molecular docking 
Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection被引量：1
《Chemical Research in Chinese Universities》2014年第6期953-958,共6页CHEN Jiawen XU Lin SUN Shiyang ZHANG Huafei MA Tonghui SU Weiheng JIANG Chunlai 
In this paper, cinobufagin and resibufogenin were found to inhibit enterovirus 71（EV71） infection in vitro in cell viability and plaque reduction assays. The 50% inhibitory concentrations（lCs0） of einobufagin and ...
关键词：Enterovirus 71 Coxsackievirus A16 CINOBUFAGIN RESIBUFOGENIN Chansu 
Intestinal Transport and Biotransformation of Resibufogenin and Cinobufagin in Chan Su via HPLC/APCI-MS^n被引量：2
《Chemical Research in Chinese Universities》2011年第3期380-384,共5页HAN Tian-jiao WANG Qing SONG Feng-rui LIU Zhong-ying LIU Zhi-qiang LIU Shu-ying 
Supported by the National Natural Science Foundation of China(Nos.30772721 and 30873360)
In vitro models of human colon carcinoma cell line(Caco-2 cell monolayer) and human intestinal bacteria were used to investigate the intestinal transport and biotransformation of resibufogenin and cinobufagin in Chan ...
关键词：Chan Su RESIBUFOGENIN CINOBUFAGIN Caco-2 cell monolayer Human intestinal bacteria 
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