CINOBUFAGIN

作品数:14被引量:14H指数:2
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相关领域:医药卫生更多>>
相关机构:西南医科大学更多>>
相关期刊:《Chinese Journal of Integrative Medicine》《Journal of Hainan Medical University》《Advances in Modern Oncology Research》《International Journal of Ophthalmology(English edition)》更多>>
相关基金:国家自然科学基金广东省自然科学基金更多>>
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Efficacy and Safety of Huachansu Capsules for the Treatment of Esophageal Cancer: A Systematic Review and Meta-analysis被引量:1
《World Journal of Traditional Chinese Medicine》2023年第3期270-277,共8页Meng-Meng Wang Xing-Hui Zhang Jun-Yan Wang Jing Xu Ming-Zhu Chen Shu-Yue Wang Min Jia Zhi-Wen Shen Ling-Jian Zhang Yang Gong Jian Gong 
The objective of this study was to systematically evaluate the efficacy and safety of Huachansu capsules in the treatment of esophageal cancer.We searched all relevant Chine se and English documents in the Cochrane Li...
关键词:CINOBUFAGIN EFFICACY esophageal cancer META-ANALYSIS safety 
Systematic evaluation and meta-analysis of the efficacy and safety of cinobufagin injection combined with western medicine in the treatment of liver cancer
《Journal of Hainan Medical University》2023年第6期51-61,共11页REN Si-si FAN Yu GUO Dong-yan ZHAI Bing-tao LI Jing-tao SHI Xiao-yan DUAN Li-fang 
Shaanxi University of Traditional Chinese Medicine Innovation Team Project(2019-YL14,2019-YL11)。
Objective:To evaluate the clinical efficacy and safety of cinobufagin injection in the treatment of liver cancer.Methods:PubMed database,Embase database and Cochrane Library database,CNKI,Wanfang database,VIP database...
关键词:Cinobufagin injection Primary liver cancer META-ANALYSIS EFFECTIVENESS SECURITY 
Meta-analysis of Cinobufagin Capsules combined with chemotherapy in treating gastric cancer
《Journal of Hainan Medical University》2021年第12期14-19,共6页Yan-Ping Ge Yong Xu Lei Zhu Jing Xing Hong Shen 
National natural science foundation(No.81703943)。
Objective:To evaluate the efficacy and safety of Cinobufagin capsules combined with chemotherapy in the treatment of gastric cancer by Meta-analysis.Methods:Randomized controlled trials(RCTs)of Cinobufagin capsules co...
关键词:Cinobufagin Capsules CHEMOTHERAPY Gastric cancer META-ANALYSIS 
A clinical study on the prevention of phlebitis caused by Cinobufagin using hand exercise combined with Jinhuang ointment
《TMR Integrative Nursing》2020年第3期91-96,共6页Yan-Li Min Yan-Ping Wang 
Objective:The aim of this study is to observe the clinical effect of hand exercise combined with jinhuang ointment on the prevention of phlebitis due to cinobufagin.Methods:A total of 90 cancer patients who have been ...
关键词:Hand exercise Jinhuang ointment CINOBUFAGIN PHLEBITIS 
Clinical Study on TACE Combined with Elemene Injection and Cinobufagin Injection Respectively for Middle and Advanced Primary Hepatic Carcinoma
《Advances in Modern Oncology Research》2020年第3期1-5,共5页Xinyue Cui Zhizhong Ma 
Objective: To observe and compare the differences in the clinical effect and the incidences of adverse reactions oftranscatheter arterial chemoembolization(TACE) combined with elemene injection and cinobufagin injecti...
关键词:Middle and advanced primary hepatic carcinoma Elemene injection Cinobufagin injection Transcatheter arterial chemoembolization Liver function Alpha-fetoprotein Tumor volume Adverse reactions 
Cinobufagin, a bufadienolide from traditional Chinese medicine Bufo bufo gargarizans CANTOR, inhibits PC3 cell growth in vitro and in vivo被引量:5
《Journal of Traditional Chinese Medical Sciences》2019年第2期175-183,共9页Tianli Niu Liye Zhao Xuyao Lin Yangkai Cai Shuhui Chen Mingkai Wang Li Zhou Hongyang Ding Xiaohan Yu Guozheng Qin 
This study was supported by the National Natural Science Foundation of China(81260540).
Objective:To explore the effects of cinobufagin (CBF),an active component of toad venom (Bufo bufo gargarizans CANTOR),on the proliferation and apoptosis of PC3 human prostate cancer cells in vitro and preliminarily i...
关键词:Prostate cancer CINOBUFAGIN CELL proliferation CELL apoptosis MCL-1 
Synthesis and Cytotoxic Activities of Spin-labeled Derivatives of Cinobufagin
《Chemical Research in Chinese Universities》2017年第4期581-586,共6页GUO Jinhua TAN Bei YE Qingmei LIANG Guangping YI Min JIANG Renwang 
Supported by the National Natural Science Foundation of China(No. 81573315), the Natural Science Foundation of Guangdong Province, China(No.2015A030313313), the Guangzhou Industry-University Collaborative Innovation Major Projects, China(No.201508030016) and the Natural Science Foundation of Hainan Province, China(No.817307).
Two series of novel spin-labeled derivatives of Cinobufagin(compounds 5 and 8a--8f in series 1 with five-membered ring nitroxyl free radical and compounds 6 and 9a-9f in series 2 with six-membered ring nitroxyl free ...
关键词:Cmobufagin Nitroxyl free radical Spin-labeled Cytotoxic activity 
Novel Cinobufagin Oxime Ether Derivatives as Potential Na+/K+-ATPase Inhibitors: Synthesis, Biological Screening and Molecular Docking被引量:1
《Chemical Research in Chinese Universities》2017年第3期378-383,共6页LIANG Guangping CHUNG Tseyu GUO Jinhua ZHANG Rongrong XU Wei TZEN Jason T.C JIANG Renwang 
Supported by the National Natural Science Foundation of China(No.81573315), the Guangdong Natural Science Fund, China(No.2015A030313313) and the Guangzhou Industry-University Collaborative Innovation Major Projects, China(No. 201508030016).
Some cinobufagin oxime ether derivatives as potential Na+/K+-ATPase inkibitors were synthesized by following the side chain of istaroxime. These compounds inhibit Na+/K+-ATPase in a dose-dependent manner. Compound...
关键词:CINOBUFAGIN Istaroxime Na+/K+-ATPase Molecular docking 
Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection被引量:1
《Chemical Research in Chinese Universities》2014年第6期953-958,共6页CHEN Jiawen XU Lin SUN Shiyang ZHANG Huafei MA Tonghui SU Weiheng JIANG Chunlai 
In this paper, cinobufagin and resibufogenin were found to inhibit enterovirus 71(EV71) infection in vitro in cell viability and plaque reduction assays. The 50% inhibitory concentrations(lCs0) of einobufagin and ...
关键词:Enterovirus 71 Coxsackievirus A16 CINOBUFAGIN RESIBUFOGENIN Chansu 
Crystal Structure and Anticancer Properties of Cinobufagin 3-Hemisuberate Methyl Ester被引量:1
《Chinese Journal of Structural Chemistry》2014年第5期790-794,共5页张冤 冯娟 叶文才 田海妍 江仁望 
supported by the National Natural Science Foundation of China(81102518)
The title compound cinobufagin 3-hemisuberate methyl ester(1) was isolated from the venom of Bufo bufo gargarizans CANTOR. The crystal structure of 1, C35H48O9, was determined by single-crystal X-ray diffraction ana...
关键词:crystal structure cinobufagin 3-hemisuberate methyl ester ANTICANCER 
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