ENDOPEROXIDES

作品数：3被引量：1H指数：1
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相关作者：杨笛更多>>
相关机构：南京医科大学更多>>
相关期刊：《Science China Chemistry》《Smart Molecules》《CCS Chemistry》更多>>
相关基金：国家自然科学基金更多>>
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Benzothiazole-endoperoxide conjugates protect PC12 cells againstβ-amyloid-induced cell death via singlet oxygen mediated oxidative detoxification of fibrils
《Smart Molecules》2024年第2期111-118,共8页Hao Wu Lei Wang Xiao Qian Wanwan Wang Yu Si Rensong Sun Engin U.Akkaya 
supported by the National Natural Science Foundation of China(22178048,22007008);the LiaoNing Revitalization Talents Program(XLYC1902001,XLYC1907021);the Fundamental Research Funds for the Central Universities(DUT18RC(3)062,DUT19RC(3)009,DUT23YG120).
Metastable endoperoxides with beta-amyloid fibrils targeting benzothiazole moieties were designed and synthesized.Singlet oxygen released from these endoperoxides by thermal cycloreversion reaction was shown to cause ...
关键词：β-amyloid protein Alzheimer's disease BENZOTHIAZOLE ENDOPEROXIDES singlet oxygen 
A Singlet Oxygen Reservoir Based on Poly-Pyridone and Porphyrin Nanoscale Metal-Organic Framework for Cancer Therapy被引量：1
《CCS Chemistry》2021年第5期1187-1202,共16页Bo-Ru Xie Chu-Xin Li Yun Yu Jin-Yue Zeng Ming-Kang Zhang Xiao-Shuang Wang Xuan Zeng Xian-Zheng Zhang 
This study was supported by the National Natural Science Foundation of China(nos.51833007,51873162,21721005,and 51690152).
Here,a methacrylate-modified pyridone derivative(mPYR)was loaded into a porphyrin nanoscale metal-organic framework(porphyrin-nMOF).Then,the loaded mPYR was further polymerized to obtain poly-pyridone(poly-mPYR)to for...
关键词：cancer ENDOPEROXIDES pyridone derivative metal-organic framework PHOTODYNAMICTHERAPY 
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