supported in part by the National Natural Science Foundation of China,No.61361160415,81271684,81501570;the Major State Basic Research Development of China(973 Program),No.2011CB013304;the Medicine-Engineering Interdisciplinary Research Grant from Shanghai Jiao Tong University in China,No.YG2014ZD09;a grant from the Youth Eastern Scholar Program at Shanghai Institutions of Higher Learning in China,No.QD2015007
Essential tremor, also referred to as familial tremor, is an autosomal dominant genetic disease and the most common movement disorder. It typically involves a postural and motor tremor of the hands, head or other part...
supported by Direct Grant (Project No.2030392) of the Chinese University of Hong Kong;HK Spinal Cord Injury Foundation;National Key Basic Research Support Foundation (973 Project: 2011CB504402)
The neurotrophin receptor (p75) activates the c-Jun N-terminal kinase (JNK) pathway. Activation of JNK and its substrate c-Jun can cause apoptosis. Here we evaluate the role of p75 in spinal motoneurons by compari...